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Data Resource Profile: The Systemic Anti-Cancer Therapy (SACT) dataset

The Systemic Anti-Cancer Therapy (SACT) database is a population-based resource of SACT activity reported routinely by National Health Service (NHS) trusts in England. Data are collected on the SACT treatments of adult and paediatric patients, delivered in secondary and tertiary settings with the intention of improving survival, delaying further cancer progression or development and improving dise

https://www.lupop.lu.se/article/data-resource-profile-systemic-anti-cancer-therapy-sact-dataset - 2025-11-03

Abatacept in rheumatoid arthritis: survival on drug, clinical outcomes, and their predictors—data from a large national quality register

There are limited data regarding efficacy of abatacept treatment for rheumatoid arthritis (RA) outside clinical trials. Quality registers have been useful for observational studies on tumor necrosis factor inhibition in clinical practice. The aim of this study was to investigate clinical efficacy and tolerability of abatacept in RA, using a national register. New publication in BMC Arthritis Resea

https://www.lupop.lu.se/article/abatacept-rheumatoid-arthritis-survival-drug-clinical-outcomes-and-their-predictors-data-large - 2025-11-03

Data Resource Profile: National Cancer Registration Dataset in England

The National Cancer Registration and Analysis Service (NCRAS), part of Public Health England (PHE), is the population-based cancer registry for England. It collects, quality assures and analyses data on all people living in England who are diagnosed with malignant and pre-malignant neoplasms, with national coverage since 1971. It produces the national cancer registration dataset for England. The p

https://www.lupop.lu.se/article/data-resource-profile-national-cancer-registration-dataset-england - 2025-11-03

Risk of local recurrence of rectal cancer and circumferential resection margin: population‐based cohort study

A circumferential resection margin (CRM) of 1·0 mm or less after rectal cancer surgery is thought to increase the risk of local recurrence (LR). This retrospective population‐based study examined how CRM distance affects the LR risk. New publication in BJS Society

https://www.lupop.lu.se/article/risk-local-recurrence-rectal-cancer-and-circumferential-resection-margin-population-based-cohort - 2025-11-03

Data Resource Profile: The National Cancer Institute’s Health Information National Trends Survey (HINTS)

The National Cancer Institute’s (NCI) Health Information National Trends Survey (HINTS) was conceived in 1997 during a multidisciplinary conference focused on risk communication with attenders representing the fields of psychology, health behaviour and education, public health, clinical medicine and health journalism. The key recommendation born of this conference encouraged NCI to develop a commu

https://www.lupop.lu.se/article/data-resource-profile-national-cancer-institutes-health-information-national-trends-survey-hints - 2025-11-03

Covid-19 i trångbodda förorter

Genom ett gemensamt initiativ från Arbets-och miljömedicin i Stockholm, Göteborg och Lund har en tvärprofessionell arbetsgrupp bildats för att utifrån Folkhälsomyndighetens och Världshälsoorganisationens (WHO) riktlinjer ta fram anpassade hälsoråd till personer och familjer med boende i förorter och andra områden med stora förutsättningar för smittspridning. Läs mer på https://www.lupop.lu.se/ART.

https://www.lupop.lu.se/article/covid-19-i-trangbodda-fororter - 2025-11-03

Formas akututlysning 2020

Med anledning av Covid-19 och den rådande utvecklingen i Sverige och världen har Formas forskarråd beslutat att omgående öppna akututlysningen 2020. Formas vill inom rådets ansvarsområden, ge möjligheten att samla in data/forskningsmaterial av akut karaktär för att säkerställa framtida tillgänglighet för forskning. Läs mer på https://www.formas.se/arkiv/alla-utlysningar/utlysningar/2020-03-26-aku…

https://www.lupop.lu.se/article/formas-akututlysning-2020 - 2025-11-03

Reflection on modern methods: five myths about measurement error in epidemiological research

Epidemiologists are often confronted with datasets to analyse which contain measurement error due to, for instance, mistaken data entries, inaccurate recordings and measurement instrument or procedural errors. If the effect of measurement error is misjudged, the data analyses are hampered and the validity of the study’s inferences may be affected. In this paper, we describe five myths that contrib

https://www.lupop.lu.se/article/reflection-modern-methods-five-myths-about-measurement-error-epidemiological-research - 2025-11-03

About consent and old data

Updated FAQ regarding personal data on LU's project blog Påverkar dataskyddsförordningen hur vi behandlar gamla personuppgifterNär och hur bör vi använda samtycke som rättslig grund för behandling av personuppgifterVad gäller för gamla samtycken?Svaren hittar du på: https://personuppgifter.blogg.lu.se/faq/============Does the General Data Protection Regulation affect how we process old personal da

https://www.lupop.lu.se/article/about-consent-and-old-data - 2025-11-03

Using four different clinical tools as predictors for pain after total hip arthroplasty: a prospective cohort study

Treatment of postoperative pain remains a significant clinical problem, and prediction of patients with a risk of higher postoperative pain levels is an important focus. We aimed to identify patients undergoing total hip arthroplasty (THA) with risk of higher pain levels at 24 h postoperatively by using four simple and easily available clinical tools. New publication in BMC Anesthesiology

https://www.lupop.lu.se/article/using-four-different-clinical-tools-predictors-pain-after-total-hip-arthroplasty-prospective-cohort - 2025-11-03

Concussion incidence and recovery in Swedish elite soccer — Prolonged recovery in female players

Sport‐related concussions are an increasingly recognized health problem. Soccer is the most popular sport in the world although recent studies on concussion incidence are scarce. Here, a nationwide prospective study on concussion incidence, symptom severity, risk factors, gender differences, and return‐to‐play after concussion was performed in 51 Swedish elite soccer teams during the 2017 season.

https://www.lupop.lu.se/article/concussion-incidence-and-recovery-swedish-elite-soccer-prolonged-recovery-female-players - 2025-11-03

Association Between Neighborhood Deprivation and Heart Failure Among Patients With Diabetes Mellitus: A 10-Year Follow-Up Study in Sweden

The study population included adults (n = 434,542) aged 30 years or older with DM followed from 2005 to 2015 in Sweden for incident HF. The association between neighborhood deprivation and the outcome was explored using Cox regression analysis, with hazard ratios (HRs) and 95% confidence intervals (95% CIs). All models were conducted in both men and women and adjusted for age, educational level, f

https://www.lupop.lu.se/article/association-between-neighborhood-deprivation-and-heart-failure-among-patients-diabetes-mellitus-10 - 2025-11-03

10-year symposium of SIMSAM

Theme: "The future of Swedish register-based research" By the end of 2018 the Swedish Initiative for Research on Microdata in the Social And Medical Sciences (SIMSAM), funded by the Swedish Research Council, has been active for 10 years. This will be acknowledged by a free open national one-day symposium in Stockholm 16 May reflecting on how the achievements and experiences of SIMSAM and other par

https://www.lupop.lu.se/article/10-year-symposium-simsam - 2025-11-03

Changes in bone mineral density over 10 years in patients with early rheumatoid arthritis

Consecutive patients with early RA (symptom duration <12 months) were followed according to a structured programme and examined with dual-energy X-ray absorptiometry (DXA) at inclusion and after 2, 5 and 10 years. Mean Z-scores over the study period were estimated using mixed linear effect models. Changes in Z-scores between follow-up visits were analysed using paired T-tests. New publication in R

https://www.lupop.lu.se/article/changes-bone-mineral-density-over-10-years-patients-early-rheumatoid-arthritis - 2025-11-03

Risk of Stroke in Patients With Atrial Fibrillation Is Associated With Stroke in Siblings: A Nationwide Study

It remains unclear whether heritable factors can contribute to risk stratification for ischemic stroke in patients with atrial fibrillation (AF). We examined whether having a sibling with ischemic stroke was associated with increased risk of ischemic stroke and mortality in patients with AF. New publication in JAHA

https://www.lupop.lu.se/article/risk-stroke-patients-atrial-fibrillation-associated-stroke-siblings-nationwide-study - 2025-11-03

Whole-Exome Sequencing in 22 Young Ischemic Stroke Patients With Familial Clustering of Stroke

We performed whole-exome sequencing in 22 probands, under 56 years at their first ischemic stroke episode, from multi-incident stroke families. With the use of a comprehensive stroke-gene panel, we searched for variants in stroke-related genes. The probands’ clinical stroke subtype was related to clinical characteristics previously associated with pathogenic variants in these genes. New publicatio

https://www.lupop.lu.se/article/whole-exome-sequencing-22-young-ischemic-stroke-patients-familial-clustering-stroke - 2025-11-03

Risk of bacteremia in patients presenting with shaking chills and vomiting - a prospective cohort study

Chills and vomiting have traditionally been associated with severe bacterial infections and bacteremia. However, few modern studies have in a prospective way evaluated the association of these signs with bacteremia, which is the aim of this prospective, multicenter study. Patients presenting to the emergency department with at least one affected vital sign (increased respiratory rate, increased he

https://www.lupop.lu.se/article/risk-bacteremia-patients-presenting-shaking-chills-and-vomiting-prospective-cohort-study - 2025-11-03