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Preterm birth has been associated with elevated blood pressure early in life; however, hypertension risks from childhood into adulthood remain unclear. We conducted a large population-based study to examine gestational age at birth in relation to hypertension risks from childhood into adulthood. New publication in European Heart Journal

https://www.lupop.lu.se/article/risk-hypertension-adulthood-persons-born-prematurely-national-cohort-study - 2025-11-05

Patients with an emergency admission for diverticular disease to any Norwegian hospital between 1 January 2008 and 31 December 2010 were included through identification in the Norwegian Patient Registry using International Classification of Diseases (ICD‐10) codes K57.1‐9. To estimate the age‐specific distribution of CT‐verified acute uncomplicated diverticulitis (AUD) and acute complicated divert

https://www.lupop.lu.se/article/risk-colorectal-cancer-following-ct-verified-acute-diverticulitis-nationwide-population-based-cohort - 2025-11-05

The use of patient‐reported outcome (PRO) measured outside clinical trials is not well defined. We report the first analysis of the prospective PRO study within the Swedish acute myeloid leukemia (AML) and the acute lymphoblastic leukemia (ALL) registries. New publication in European Journal of Haematology

https://www.lupop.lu.se/article/introducing-patient-reported-outcome-acute-leukemia-quality-registries-sweden - 2025-11-05

The number of children who were born after their parents were diagnosed with central nervous system (CNS) tumor is increasing, but it remains largely unknown regarding the academic performance of these children. We aimed to investigate whether children of survivors with childhood or adolescent CNS tumor were associated with poor academic performance. Children of survivors of CNS tumor were identif

https://www.lupop.lu.se/article/poor-academic-performance-offspring-survivors-childhood-or-adolescent-central-nervous-system-tumor - 2025-11-05

We seek to identify factors that facilitate or inhibit transmission of drug abuse (DA) from high-risk parents to their children. In 44,250 offspring of these parents, ascertained from a Swedish national sample for having a mother and/or father with DA, we explored, using Cox models, how the prevalence of DA was predicted by potentially malleable risk factors in these high-risk parents, their spous

https://www.lupop.lu.se/article/facilitating-versus-inhibiting-transmission-drug-abuse-high-risk-parents-their-children-swedish - 2025-11-05

We introduce and apply an elegant, contrastive genetic-epidemiological design – Maternal Half-Sibling Families with Discordant Fathers – to clarify cross-generational transmission of genetic risk to alcohol use disorder (AUD), drug abuse (DA) and major depression (MD). New publication in Psychological Medicine

https://www.lupop.lu.se/article/maternal-half-sibling-families-discordant-fathers-contrastive-design-assessing-cross-generational - 2025-11-05

Perfluoroalkyl substances (PFASs) are widespread, bioaccumulating, and persistent and show placental transfer. Emerging research indicates associations between prenatal exposure and low birth weight. The aim of this study was to assess the associations between first trimester exposure to PFASs and birth weight (BW) in the Swedish Environmental, Longitudinal, Mother and child, Asthma and allergy (S

https://www.lupop.lu.se/article/maternal-serum-levels-perfluoroalkyl-substances-early-pregnancy-and-offspring-birth-weight - 2025-11-05

Elderly patients with acute myocardial infarction undergoing percutaneous coronary intervention are at increased risk of both ischemic and bleeding complications. The optimal anticoagulation strategy in these patients is uncertain. Therefore, we compared bivalirudin to heparin monotherapy in a contemporary cohort of such patients. New publication in Circulation: Cardiovascular Interventions

https://www.lupop.lu.se/article/bivalirudin-versus-heparin-monotherapy-elderly-patients-myocardial-infarction-prespecified-subgroup - 2025-11-05

Incidence of ST-elevation myocardial infarction (STEMI) is increasing in Nepal. We aim to describe the presentation, management, complications, and outcomes of patients admitted with a diagnosis of STEMI in Shahid Gangalal National Heart Centre (SGNHC), Nepal. New publication in Nepalese Heart Journal

https://www.lupop.lu.se/article/shahid-gangalal-national-heart-centre-st-elevation-myocardial-infarction-registry-sgnhc-stemi - 2025-11-05

There has been considerable interest in recent years in quantifying the rate of unavoidable or so‐called random cancers, as opposed to cancers linked to environmental, genetic or other factors. We propose a data‐based approach to estimate an upper limit to this probability, based on an analysis of multiple registry data. The argument is that the cumulative hazards for random cancers cannot exceed

https://www.lupop.lu.se/article/random-cancers-supported-registry-data - 2025-11-05

Deidentified data from the Australasian Collaborative Trial of Magnesium Sulphate (ACTOMgSO4) and the ACPR were linked. Children born from 1996 to 2000 at Australian hospitals who survived and had 2‐year paediatric assessments were included. Children identified with CP in: (1) both the ACTOMgSO4 (2y) and the ACPR (5y), (2) the ACTOMgSO4 only, and (3) the ACPR only were compared. New publication in

https://www.lupop.lu.se/article/linking-data-large-clinical-trial-australian-cerebral-palsy-register - 2025-11-05

The aims were to investigate the association between maternal serum levels of perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonate (PFHxS) and perfluorononanoic acid (PFNA) in early pregnancy and overweight in the child at 4 years and to assess potential heterogeneity in exposure effect between strata with different levels of other risk factors for overweight.

https://www.lupop.lu.se/article/intrauterine-exposure-perfluorinated-compounds-and-overweight-age-4-case-control-study - 2025-11-05

Population-based administrative registers are often used for research purposes. However, their potential usefulness depends on the validity of the registered information. This study assessed the validity of the recorded codes for social anxiety disorder (SAD), also known as social phobia, in the Swedish National Patient Register (NPR). New publication in BMC Psychiatry

https://www.lupop.lu.se/article/validity-and-reliability-social-anxiety-disorder-diagnoses-swedish-national-patient-register - 2025-11-05

Quantified terminal ileal motility during magnetic resonance enterography (MRE) has been suggested to be used as a biomarker of Crohn's disease (CD). The aim of the present study was to evaluate this method in clinical practice. New publication in NGM

https://www.lupop.lu.se/article/volumetric-analysis-small-bowel-motility-unselected-cohort-patients-crohns-disease - 2025-11-05

Recovery patterns of motor function and activity capacity of the upper extremity after stroke have been described, but less is known about longitudinal changes of perceived manual activity performance. The aim of this study was to investigate longitudinal changes of self-perceived manual ability at several timepoints from onset until 12 months post-stroke in a cohort of consecutively recruited ind

https://www.lupop.lu.se/article/longitudinal-changes-self-perceived-manual-ability-first-year-after-stroke-cohort-study - 2025-11-05

Earlier studies have implied a change in dietary habits of the Swedish population towards a low carbohydrate, high fat diet. Questions have been raised about the development in recent years and potential health effects. We have investigated the dietary intake of Swedish female students enrolled in a university nutrition course between 2002 and 2017. The students carried out self-reporting of all f

https://www.lupop.lu.se/article/carbohydrates-fat-trends-food-intake-among-swedish-nutrition-students-2002-2017 - 2025-11-05

To evaluate screening efficiency and suggest cut-offs for parent and child Mood and Feelings Questionnaire (MFQ) and the short version (SMFQ) in unselected help seeking child- and adolescent psychiatric outpatients for subgroups of 6–12 versus 13–17 year olds and boys versus girls. New publication in PLOS ONE

https://www.lupop.lu.se/article/screening-efficiency-mood-and-feelings-questionnaire-mfq-and-short-mood-and-feelings-questionnaire - 2025-11-05

The outbreak of SARS-CoV-2 is the worst healthcare emergency of this century, and its impact on pediatrics and neonatology is still largely unknown. The European Society for Pediatric and Neonatal Intensive Care (ESPNIC) launched the EPICENTRE (ESPNIC Covid pEdiatric Neonatal Registry) international, multicenter, and multidisciplinary initiative to study the epidemiology, clinical course, and outc

https://www.lupop.lu.se/article/epicentre-espnic-covid-pediatric-neonatal-registry-initiative-background-and-protocol-international - 2025-11-05

Pancreatic cancer is a devastating disease with a dismal prognosis. Despite profound medical advances in systemic therapies for other types of aggressive tumours during recent years, a diagnosis of pancreatic cancer is still often synonymous with a fatal outcome. The term periampullary cancer includes pancreatic cancer and applies to the group of tumours found in proximity to the ampulla of Vater.

https://www.lupop.lu.se/article/chemotherapy-host-response-and-molecular-dynamics-periampullary-cancer-champ-study - 2025-11-05

The real burden of human cystic echinococcosis (CE) remains elusive, due to the peculiar characteristics of the disease and the heterogeneous and incomplete data recording of clinical cases. Furthermore, official notification systems do not collect pivotal clinical information, which would allow the comparison of different treatment outcomes, and thus circumvent the difficulty of implementing clin

https://www.lupop.lu.se/article/european-register-cystic-echinococcosis-erce-state-art-five-years-after-its-launch - 2025-11-05