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Exploring the role of YAP and TAZ in the lung epithelium: a Ph.D. Interview with Hani Alsafadi

Published 27 February 2023 Hani Alsafadi defended his Ph.D. thesis on the 13th of February, 2023. With a longstanding interest in biomedical research and a passion for better understanding one of the least regenerative organs in the body, the lung, he has spent the past four years helping to uncover some of the mechanisms that may drive a lung disease currently without a cure, idiopathic pulmonary

https://www.stemcellcenter.lu.se/article/exploring-role-yap-and-taz-lung-epithelium-phd-interview-hani-alsafadi - 2025-02-17

Shining the spotlight on rare disease research

Published 28 February 2023 ​​​​​​​Did you know that about 70% of rare diseases begin in childhood? How about that 1 in 5 cancers are considered a rare disease? Or that nearly three-quarters of all rare diseases are genetic diseases? With more than 6,000 rare diseases known to impact the lives of an estimated 300 million people around the world – rare diseases are all too common. Limited knowledge

https://www.stemcellcenter.lu.se/article/shining-spotlight-rare-disease-research - 2025-02-17

First patient receives milestone stem cell-based transplant for Parkinson’s Disease

By press [at] med [dot] lu [dot] se (Tove Smeds) - published 1 March 2023 On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund Stem Cell Center researchers at Lund University and it is now being tested in patients for the first time. The transplantation product i

https://www.stemcellcenter.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-02-17

New methods for phenotypic antibody discovery: a Ph.D. Interview with Jenny Mattsson

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 6 March 2023 On 03 March 2023, Jenny Mattsson defended her Ph.D. thesis. With the goal to broaden the availability of antibody-based drugs for patients with cancer and other diseases, she has spent the past several years working to develop new methods that can be used to identify new antibodies and antibody targets. In

https://www.stemcellcenter.lu.se/article/new-methods-phenotypic-antibody-discovery-phd-interview-jenny-mattsson - 2025-02-17

Inspiring tomorrow's scientists: Students explore the world of stem cells on UniStem Day 2023

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 21 March 2023 Highschool students learn how the extraordinary regenerative powers of salamanders can help us discover new ways to fight diseases in humans in a UniStem Day 2023 workshop led by researchers in the Leigh Group. Have you ever wondered what it takes to grow a brain in a petri dish or how scientists use viru

https://www.stemcellcenter.lu.se/article/inspiring-tomorrows-scientists - 2025-02-17

Eggs can help us understand neuroblastoma

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 29 March 2023 Sofie Mohlin's research focuses on neuroblastoma. Photo: Åsa Hansdotter. There is a large carton of chicken eggs on the bench in Sofie Mohlin's laboratory. They have been delivered during the morning and soon they will be placed in the 37-degree heat of the incubator so that the embryo can develop. Alread

https://www.stemcellcenter.lu.se/article/eggs-can-help-us-understand-neuroblastoma - 2025-02-17

What makes blood stem cells transform? Regulation of RNA splicing may be an answer.

By press [at] med [dot] lu [dot] se (Faculty of Medicine) - published 24 March 2023 Cristian Bellodi and Maciej Cieśla. Photo: Helena Fritz Researchers at Lund Stem Cell Center and Lund University's Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published i

https://www.stemcellcenter.lu.se/article/what-makes-blood-stem-cells-transform-regulation-rna-splicing-may-be-answer - 2025-02-17

From vision to reality: 20 years of cutting-edge research at Lund Stem Cell Center

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 13 April 2023 In 2023, the Lund Stem Cell Center turns 20 years old. This will be celebrated with a conference attended by some of the world's leading stem cell researchers. Image: iStock/Maksim Tkachenko For two decades, researchers at Lund University's strategic research area, Lund Stem Cell Center, have focused on d

https://www.stemcellcenter.lu.se/article/vision-reality-20-years-cutting-edge-research-lund-stem-cell-center - 2025-02-17

Interdisciplinary Teams Unite to Develop Patient-Specific Disease Models

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 28 April 2023 Researchers from Lund Stem Cell Center are coming together with colleagues across Lund University to shape the future of healthcare. A new University-wide seed funding initiative seeking to support emerging research topics that benefit society will see interdisciplinary teams of neuroscience, medicine, an

https://www.stemcellcenter.lu.se/article/interdisciplinary-teams-lund-university-unite-develop-patient-tailored-disease-models - 2025-02-17

Decoding the Inner Workings of a Blood Stem Cell-Boosting Molecule

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 24 May 2023 A model of a proteasome, a protein complex which degrades unneeded or damaged proteins. Image from: Getty Images. A recent study conducted by researchers at Lund University's Lund Stem Cell Center, and published in the Journal of Biological Chemistry, has unraveled the intricate inner workings of UM171—a mo

https://www.stemcellcenter.lu.se/article/decoding-inner-workings-blood-stem-cell-boosting-molecule - 2025-02-17

New Study Reveals Astrocytes' Role in Frontotemporal Dementia

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 31 May 2023 An image of co-cultures with neuronal projections in purple and astrocytes in green. Image credit: Isaac Canals. Lund Stem Cell Center researchers have published a new study that reveals the role of astrocytes in the development of frontotemporal dementia (FTD). Their findings, now in the journal Brain Comm

https://www.stemcellcenter.lu.se/article/new-study-reveals-astrocytes-role-frontotemporal-dementia - 2025-02-17

Investigating a cell replacement therapy for Parkinson's Disease: a Ph.D. Interview with Fredrik Nilsson

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 8 June 2023 Fredrik Nilsson successfully defended his Ph.D. thesis on May 10, 2023. For the last four years, Fredrik has explored the use of patient-specific cells in cell replacement therapy for Parkinson's disease to identify strategies to safeguard these transplanted cells from disease-related degeneration. In this

https://www.stemcellcenter.lu.se/article/investigating-cell-replacement-therapy-parkinsons-disease-phd-interview-fredrik-nilsson - 2025-02-17

Stem Cell Science Through the Lens of Art

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 9 June 2023 Lund Stem Cell Center recently hosted its Image Competition for 2023, providing a glimpse into the diverse world of stem cell science through the lens of art. The competition showcased the dedication, creativity, and scientific excellence that continue to drive our pursuit of knowledge in stem cell research

https://www.stemcellcenter.lu.se/article/stem-cell-science-through-lens-art - 2025-02-17

Exploring the Role of 'Jumping Genes' in X-Linked Dystonia-Parkinsonism

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 19 June 2023 Postdoctoral researcher Vivien Horvath investigates X-Linked Dystonia-Parkinsonism (XDP), a rare neurodegenerative disorder. New research is underway at Lund University, led by Dr. Vivien Horvath, a postdoctoral researcher at Lund Stem Cell Center. Supported by a new grant from the Collaborative Center for

https://www.stemcellcenter.lu.se/article/exploring-role-jumping-genes-x-linked-dystonia-parkinsonism - 2025-02-17

Mechanisms of Initiation and Suppression in Pediatric Leukemia: a Ph.D. Interview with Mohamed Eldeeb

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 22 June 2023 Mohamed Eldeeb defended his Ph.D. thesis on June 9, 2023. With a passion for scientific discovery with clinical impact, Mohamed has dedicated the last four years to unraveling the mysteries as to why some children develop pediatric leukemia and others don’t. His research shed light on the mechanisms that p

https://www.stemcellcenter.lu.se/article/mechanisms-initiation-and-suppression-pediatric-leukemia-phd-interview-mohamed-eldeeb - 2025-02-17

Targeted Therapies in Leukemia Research Group Joins Lund Stem Cell Center

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 27 June 2023 Lund Stem Cell Center welcomes the Targeted Therapies in Leukemia Research Group, led by molecular biologist Marcus Järås, as its newest member. With a strong background in translational research and a focus on developing innovative therapies, the group brings extensive expertise and a unique perspective t

https://www.stemcellcenter.lu.se/article/targeted-therapies-leukemia-research-group-joins-lund-stem-cell-center - 2025-02-17

New ATMP Center at Lund University

By katrin [dot] stahl [at] med [dot] lu [dot] se (Katrin Ståhl) - published 10 July 2023 Lund University is establishing a university-wide development center for advanced therapies, LU-ATMP. It is an effort to move medical research with the potential for new groundbreaking therapies to reach patient groups where traditional medicines are not enough. "We want to contribute to the vision of Sweden b

https://www.stemcellcenter.lu.se/article/new-atmp-center-lund-university - 2025-02-17

Cracking the Code of Human Brain Evolution: Patricia Gerdes Awarded MSCA Fellowship

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 8 August 2023 Patricia Gerdes is developing mini-brain models called organoids using induced pluripotent stem cells from blood or skin samples from rhesus macaques, chimpanzees, and human donors. The image on the right shows an example of a rhesus macaque organoid. Patricia Gerdes, a postdoctoral researcher specializin

https://www.stemcellcenter.lu.se/article/cracking-code-human-brain-evolution-patricia-gerdes-awarded-msca-fellowship - 2025-02-17

EU funding for killer cells that fight cancer

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 24 August 2023 Researchers at Lund University, Rigshospitalet Copenhagen, Hannover Medical School and the biopharma company Amniotics will investigate how natural killer cells can be tailored for the treatment of AML, glioblastoma and pancreatic cancer. Photo: iStock. As certain tumor cells are able to conceal themselv

https://www.stemcellcenter.lu.se/article/eu-funding-killer-cells-fight-cancer - 2025-02-17

Stem cell researcher Anna Falk heads Lund University's Center for Advanced Therapies

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 11 September 2023 Anna Falk. Photo: Tove Smeds. Anna Falk, professor at Lund University's Stem Cell Center, will be the director of the newly established Center for Advanced Therapies, LU-ATMP. "My vision is that we will accelerate the development of all the advanced therapies underway at Lund University. Together with the hea

https://www.stemcellcenter.lu.se/article/stem-cell-researcher-anna-falk-heads-lund-universitys-center-advanced-therapies - 2025-02-17