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The majority of patients with type 2 diabetes who undergo a gastric bypass operation recover from the disease within a few days of the operation, long before their body weight falls. No one knows how this happens, but researchers at Lund University Diabetes Centre in Sweden have now come up with a partial answer. In the long term, we aim to identify new treatment strategies that could imitate the

https://www.ludc.lu.se/article/early-partial-answer-why-obesity-operations-cause-remission-diabetes - 2025-11-19

In recent years, researchers have discovered around 70 genetic risk variants for diabetes, but still TCF7L2, known as the diabetes gene, is the gene that carries with it the largest risk of developing type 2 diabetes. Using a new method called exon skipping, Ola Hansson at Lund University Diabetes Centre (LUDC) wants to learn more about TCF7L2 by studying new ways of delaying the onset of type 2 d

https://www.ludc.lu.se/article/method-which-repairs-damaged-genes - 2025-11-19

Using a simple blood sample, it is now possible to identify people at risk of developing type 2 diabetes in the future. In a new project, Anders Rosengren, researcher at Lund University Diabetes Centre and physician at Skåne University Hospital in Malmö, has identified a new risk protein for type 2 diabetes. Anders Rosengren is one of four researchers who was awarded 50 000 euro from the Hjelt Fou

https://www.ludc.lu.se/article/inflammation-inhibitorial-medicines-will-prevent-type-2 - 2025-11-19

Researchers at Lund University in Sweden have discovered how to stop the destructive process that leads to cardiovascular disease in diabetic laboratory animals. It is well known that high blood sugar levels significantly raise the risk of cardiovascular disease. It is unclear, however, why this happens. An important part of the explanation may be NFAT, a protein activated when blood sugar is rais

https://www.ludc.lu.se/article/protein-block-stops-vascular-damage-diabetes - 2025-11-19

Researchers at Lund University in Sweden have developed a new mouse model that answers the question of what actually happens in the body when type 2 diabetes develops and how the body responds to drug treatment. Long-term studies of the middle-aged mouse model will be better than previous studies at confirming how drugs for type 2 diabetes function in humans. “The animal models for type 2 diabetes

https://www.ludc.lu.se/article/new-mouse-model-confirms-how-type-2-diabetes-develops - 2025-11-19

Exercise, even in small doses, changes the expression of our innate DNA. New research from Lund University in Sweden has described for the first time what happens on an epigenetic level in fat cells when we undertake physical activity. “Our study shows the positive effects of exercise, because the epigenetic pattern of genes that affect fat storage in the body changes”, says Charlotte Ling, Associ

https://www.ludc.lu.se/article/epigenetic-changes-fat-cells-following-exercise - 2025-11-19

Is it time for a new nutritional supplement during pregnancy to prevent type 1 diabetes in the unborn child? Two new scientific studies, one from Lund University in Sweden, and another from Finland, suggest so. The research groups have analysed blood samples from umbilical cords and compared the level of a group of fats known as phospholipids. The results of the studies show that low levels of pho

https://www.ludc.lu.se/article/could-supplements-during-pregnancy-reduce-child-diabetes-risk - 2025-11-19

With around 350 million patients worldwide, diabetes is one of the world’s major public health problems. This year’s Fernström Foundation Nordic Prize, with prize money of SEK 1 million, goes to the internationally renowned diabetes researcher Leif Groop from Lund University in Sweden. Leif Groop’s speciality has been referred to as ‘gene fishing’. It involves fishing up the genes that contribute

https://www.ludc.lu.se/article/major-prize-lu-diabetes-researcher - 2025-11-19

Marju Orho-Melander, professor in genetic epidemiology at Lund Univeristy, will receive a grant from the Swedish research Council for being an extraordinary younger scientist. 18 milliongs allocated in six years, will provide more efficiant strategies for prevention cardiometabolic diseases and cancer. - I am thankful and honoured. The grant has an important role in the feasibility of the quantity

https://www.ludc.lu.se/article/18-millions-marju-orho-melander-extraordinary-research - 2025-11-19

Professor Leif Groop, Lund University, has been awarded Söderbergska priset i medicin 2014 (the Söderberg award for medicine 2014) for his pioneering work in diabetes research both in relation to general and clinical research. “Naturally, receiving this award is hugely encouraging for me, the research group I represent, and diabetes research in general. I would like to extend a large, humble thank

https://www.ludc.lu.se/article/professor-leif-groop-lund-university-has-been-awarded-soderbergska-priset-i-medicin-2014 - 2025-11-19

Professor Leif Groop, international known diabetes researcher and coordinator of Lund University Diabetes Centre, is now assigned an other established award: Matti Äyräpää-award of 20 000 eur. The prize is awarded by the Finnish medical society Duodecim. Leif Groop who is born in Finland, has during his long carrier contributed to the increased knowledge of the genes roles when it comes to Type 2

https://www.ludc.lu.se/article/awards-leif-groop - 2025-11-19

It is well known that type 2 diabetes raises the risk of dementia. The reasons for this are less clear, but one explanation could be insulin resistance in the brain, according to Malin Wennström, a researcher at Lund University´s Molecular Memory Research Unit. She has received EUR 700,000 from the Swedish Research Council to investigate her theory."The goal is to find measureable biomarkers early

https://www.ludc.lu.se/article/diabetes-link-dementia-be-examined - 2025-11-19

The majority of gastic bypass patients mysterioulsy recover from their type 2 diabetes within days, before any weight loss has taken place. A study at Lund University Diabetes Centre in Sweden has now shown that the insulin-producing beta cells increase in number and performance after the surgery. “We have suspected this for a while, but there have not previously been any models to prove it”, says

https://www.ludc.lu.se/article/new-findings-gastric-bypass-and-diabetes - 2025-11-19

Five researchers from Lund University and the University of Geneva has bedn granted altogether 200 000 Euro from Bo & Kerstin Hjelt Foundation for type 2 diabetes. Dr Jens Lagerstedt, Lund University: "Zinc transporter ZnT8 and type 2 diabetes" (€50 000)Dr Jonathan Esguerra, Lund University: "Characterization of non-coding RNAs in the pancreatic islets of Langerhans and identification of circulati

https://www.ludc.lu.se/article/grants-hjelt-foundation - 2025-11-19

People with type 2 diabetes have epigenetic changes on their DNA that healthy individuals do not have. This has been shown in a major study by researchers at Lund University. The researchers also found epigenetic changes of a large number of genes that contribute to reduced insulin production. “This shows that the risk of developing type 2 diabetes is not only genetic, but also epigenetic”, said C

https://www.ludc.lu.se/article/epigenetic-changes-could-explain-type-2-diabetes - 2025-11-19

Using magnetically controlled nanoparticles to force tumour cells to ‘commit suicide’ sounds like science fiction, but could be a future part of cancer treatment. “The clever thing about the technique is that we can target selected cells without harming surrounding tissue”, said Professor Erik Renström from Lund University. In brief, the technique involves getting the nanoparticles into a tumour c

https://www.ludc.lu.se/article/nanoparticles-cause-cancer-cells-commit-suicide - 2025-11-19

“The increased risk of diabetes has previously been explained by the fact that cystic fibrosis causes damage to the pancreas, where the blood-sugar regulating hormone insulin is produced. We are the first research group to show that the mutated gene that causes cystic fibrosis also plays an important role in the release of insulin. The risk of diabetes is not only explained by the destruction of t

https://www.ludc.lu.se/article/cystic-fibrosis-and-diabetes-link-explained - 2025-11-19

The Swedish Innovation Agency, VINNOVA, has granted 100 MSEK to the Strategic Innovation Programme, SIO Chronic Diseases, with the overall aim to create better health and increased growth in Sweden. If Sweden is to remain competitive on the global life science stage, the opportunities for turning research results into innovations providing growth and benefit for patients need to be improved. SIO C

https://www.ludc.lu.se/article/100-millions-strengthen-swedish-life-science-sector - 2025-11-19

By studying identical twins, researchers from Lund University in Sweden have identified mechanisms that could be behind the development of type 2 diabetes. This may explain cases where one identical twin develops type 2 diabetes. The study involved 14 pairs of identical twins in Sweden and Denmark. One twin had type 2 diabetes and the other was healthy.“Twins are a good model for finding mechanism

https://www.ludc.lu.se/article/study-identical-twins-reveal-type-2-diabetes-clues - 2025-11-19

Antidiabetics that also provide cardiovascular benefit is a key unmet need in diabetes treatment. ApoA-l is a protein shown to have both glucose lowering and cholesterol-lowering effects and has been investigated by Jens Lagerstedt and Karin Stenkula for its therapeutic potential. They have now received 2,5 million Danish kroner from the Novo Seeds for taking innvoation a step further. The goal is

https://www.ludc.lu.se/article/lagerstedt-and-stenkula-receive-novo-seed-grant - 2025-11-19