Purpose: To model prediction of undetected glaucoma in a predominantly white population, based on intraocular pressure (IOP) and subject age. Methods: In 1992–1997, a population screening for glaucoma was performed at Malmö University Hospital where individuals between 55–79 years of age (n = 46 614) living in Malmö, were invited to a free eye health examination. Recently examined patients were no

Background: Leishmaniasis is a neglected and poorly reported parasitic infection transmitted by sand flies in tropical and subtropical regions. Knowledge about leishmaniasis has become important in non-endemic countries due to increased migration and travel. Few studies of the clinical management of cutaneous, mucocutaneous and visceral leishmaniasis in non-endemic regions have been published to d

Fysik handlar om att försöka förstå hur världen omkring oss fungerar utifrån vissa grundläggande principer. Fasta tillståndets fysik fokuserar på de fasta material vi har omkring oss. Dessa material har olika strukturer beroende på vilka grundämnen de är uppbyggda av och hur de har bildats. Om en gas av atomer kyls ner långsamt tenderar atomerna att ordna sig i specifika regelbundna mönster, så kaIn materials with open 3$d$ and 4$f$ shells the valence electrons are relatively localized around the atoms which leads to large electron-electron correlations. These, so called strongly correlated materials, exhibit many intriguing properties such as high $T_c$ superconductivity, colossal magneto-resistance and heavy fermion behaviour. The strong electron-electron correlations make these material

Vinculin is an essential and highly conserved cell adhesion protein, found at both focal adhesions and adherens junctions, where it couples integrins or cadherins to the actin cytoskeleton. Vinculin is involved in controlling cell shape, motility, and cell survival, and has more recently been shown to play a role in force transduction. The tail domain of vinculin (Vt) contains determinants necessa

How individual cells respond to mechanical forces is of considerable interest to biologists as force affects many aspects of cell behaviour. The application of force on integrins triggers cytoskeletal rearrangements and growth of the associated adhesion complex, resulting in increased cellular stiffness, also known as reinforcement. Although RhoA has been shown to play a role during reinforcement,

The goal of this study has been to establish a method for quantifying the minimum chip thickness, h1min, during longitudinal turning of duplex stainless steel, and explore how the value of h1min changes with varying process parameters. Based on experimental results, it was found that the tool edge radius only has a limited influence on the size of h1min up to a certain feed level after which the c

Background: Based on the possible shared mechanisms of chemotherapy-induced peripheral neuropathy (CIPN) for different drugs, we aimed to aggregate results of all previously published genome-wide association studies (GWAS) on CIPN, and to replicate them within a cohort of multiple myeloma (MM) patients. Methods: Following a systematic literature search, data for CIPN associated single nucleotide p

Studies showing that large-scale public health interventions in early life have lasting consequences are still scarce and rarely disclose the mechanisms. In 1931–1946, the Swedish state reformed the childbirth institutional system that led to the openings of the new maternity wards and to the gradual decline in home deliveries assisted by midwives. Maternity wards offered improved conditions for a

Since 2010, the Chilean government has backed a progressive increase of non-conventional renewable energies sources (NCRES) to put forward the country's energy independence from fossil fuels, and therefore from imports, and to reduce its CO2 emissions. The analysis of the final energy consumptionchanges via a structural decomposition analysis, based on the Input-Output Tables for Chile in the peri

Cities are well-positioned to realize both sustainable development goals and humanrights. Policy implementation, delivery of public services, and the reproduction of inclusivesocieties take place in cities, where 80 per cent of global GDP is generated (SDSN 2016:11). Cities are also home to extreme poverty, socio-economic disparities, unsustainablepatterns of consumption and production, and human

This article uses Neil M. Denari’s HL23 condominium tower in West Chelsea, New York City, as the lens through which to focus on the architectural design pathway in discretionary reviews to negotiate architectural form and bulk restrictions. The argument states that creative architectural forms can appropriate an unorthodox site configuration in accord with planning objectives and that review proce

The proliferation of shadow housing in the post-suburban landscape of Los Angeles tells a story about the inadequacy of R1 zoning to respond to escalating calls for new and more resilient housing types. Neither romanticizing nor condemning illegal housing, this article takes the shadow houses of L.A. as context for a critical re-evaluation of the R1. By consulting the tools of architectural repres

Rising global sea level caused by melting ice sheets poses a major challenge in a persistently warming climate. The Greenland Ice Sheet (GrIS) is among the main contributors, and in order to make accurate predictions of future ice retreat and sea level rise, it is imperative to understand how the ice sheet responded to global warming in the past. Reconstructions of relative sea level (RSL) are a k

Ultrafast manipulations of magnetic phases are eliciting increasing attention from the scientific community because potentially relevant to the understanding of nonequilibrium phase transitions and to novel technologies. Here, we focus on manipulations applied to magnetic impurities in metallic hosts. By considering small nanoring geometries, we show how currents can induce a dynamical switching b