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The impact of hypoglycaemia on daily functioning among adults with diabetes : a prospective observational study using the Hypo-METRICS app

Aims/hypothesis: The aim of this work was to examine the impact of hypoglycaemia on daily functioning among adults with type 1 diabetes or insulin-treated type 2 diabetes, using the novel Hypo-METRICS app. Methods: For 70 consecutive days, 594 adults (type 1 diabetes, n=274; type 2 diabetes, n=320) completed brief morning and evening Hypo-METRICS ‘check-ins’ about their experienced hypoglycaemia a

Risk of severe esophageal stricture among childhood cancer survivors – A population-based case-cohort study within the Adult Life after Childhood Cancer in Scandinavia (ALiCCS)

Purpose: Due to limited data on treatment-related risk factors associated with esophageal stricture in childhood cancer survivors, this study aimed to assess such factors in long-term survivors. Methods: A case-cohort study was conducted involving 36 cases of five-year childhood cancer survivors with esophageal stricture and a sub-cohort of 540 survivors diagnosed with cancer in 1970–2007 as ident

A virtual geobibliography of polar tourism and climate change

The polar regions are increasingly at the center of attention as the hot spots of climate crisis as well as tourism development. The recent IPCC reports highlight several climate change risks for the rather carbon-intensive and weather-based/dependent polar tourism industry in the Arctic and the Antarctic. This study presents the scholarly state-of-knowledge on tourism and climate change in the po

A systematic evaluation of alkaliphilic microbial consortia from a soda lake for the biodegradation of cyanide-rich wastewater

Alkaliphilic microorganisms are one option for the treatment of cyanide-polluted wastewater. This study reports the degradation of cyanide from simulated gold mine wastewater using alkaliphilic microbial consortia harvested from a soda lake, Lake Chitu, Ethiopia. A novel aerobic-anoxic integrated treatment setup was established for the treatment process. Colorimetry was used to measure residual cy

Fairy Dances

Commissioned by the Florin Harp Trio. Instrumentation: oboe, cello, harp. Several concerts are planned for spring 2025.

Feasibility test of WORK-ON : a vocational rehabilitation intervention for people with chronic inflammatory arthritis

Background: People with chronic inflammatory arthritis (IA) often have a reduced work ability. Consequently, they are at high risk of losing their jobs and being permanently excluded from the labor market. Therefore, we developed a new context-specific vocational rehabilitation intervention for people with IA based on the Medical Research Council’s framework for complex interventions. This interve

Educational research in physics teacher education : the role of mathematics in physics teaching

Do student teachers benefit from contact with research, as required in our national teacher education curriculum? This paper describes the experiences of two pre-service teachers, who learned about common challenges encountered in the intersection between mathematics and physics. After a literature survey, they decided to try out a few questions with second-year high-school students (age 17). One

Co-occurrence of unhealthy lifestyle behaviours in middle-aged adults : findings from the Swedish CArdioPulmonary bioImage Study (SCAPIS)

Middle-aged adults engaging in unhealthy lifestyle behaviors are at higher risk of chronic diseases. However, little is known about the co-occurrence of these behaviors and their determinants. This cohort study examined the co-occurrence of unhealthy lifestyle behaviors (alcohol consumption, diet, physical inactivity, and smoking) in 30,154 middle-aged adults and their associations with sociodemog

Cryogenic probe technology enables multidimensional solid-state NMR of the stratum corneum without isotope labeling

Solid-state NMR has great potential for investigating molecular structure, dynamics, and organization of the stratum corneum, the outer 10–20 μm of the skin, but is hampered by the unfeasibility of isotope labelling as generally required to reach sufficient signal-to-noise ratio for the more informative multidimensional NMR techniques. In this preliminary study of pig stratum corneum at 35 °C and

Three incumbents restructuring the Swedish energy and steel regimes : the case of Hybrit

This paper addresses the role of incumbent firms in driving transitions that entail multiple sectors, conditioned by multiple regimes. We analyse the case ‘HYBRIT’, a radical innovation venture championed by three incumbents from the steel and energy regimes. We investigate what conditions the incumbents’ agency and how they enacted their agency targeting restructuring of the regime elements–actor

Controversies in employee-driven innovation : Exploring the Danish public healthcare

This article applies the lens of controversies to explore tensions in the ­interactions among different actors engaged in employee-driven innovation (EDI) in the Danish public healthcare. Semi-structured interviews were conducted with innovation executives and consultants, non-clinical professionals with managerial responsibilities, and clinical professionals. In addition, observation and document

An explainable hybrid framework for estimating daily reference evapotranspiration : Combining extreme gradient boosting with Nelder-Mead method

Accurate estimation of reference evapotranspiration (ETo) is essential for effective water resources management, irrigation system design, and various hydrological and agricultural applications. This study employed extreme gradient boosting (XGBoost) model, signal decomposition techniques, and XGBoost coupled with Nelder–Mead (NM) method to enhance ETo prediction across two meteorological stations

CSF glial biomarkers are associated with cognition in individuals at risk of Alzheimer's disease

INTRODUCTION: We examined whether baseline glial markers soluble triggering receptor expressed on myeloid cell 2 (sTREM2), chitinase 3-like protein 1 (YKL-40), and glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF), and plasma GFAP are associated with cognitive change in cognitively unimpaired (CU) individuals at risk of Alzheimer's disease (AD). METHODS: A total of 353 CU (mean a

Targeting IGF-IR improves neoadjuvant chemotherapy efficacy in breast cancers with low IGFBP7 expression

There has been a long-standing interest in targeting the type 1 insulin-like growth factor receptor (IGF-1R) signaling system in breast cancer due to its key role in neoplastic proliferation and survival. However, no IGF-1R targeting agent has shown substantial clinical benefit in controlled phase 3 trials, and no biomarker has been shown to have clinical utility in the prediction of benefit from

Synovial fibroblasts from children with oligoarticular juvenile idiopathic arthritis induce migration and prolong viability of neutrophils

Introduction: Little is known of the processes that trigger neutrophil activation in the joint of patients with oligoarticular juvenile idiopathic arthritis (oJIA), and if synovial fibroblasts (S-Fib) play an important role in the activation. Therefore, we aimed to investigate whether S-Fib derived from oJIA patients drive neutrophil activation. Methods: Synovial fluid (SF) was collected from pati

Attosecond formation of charge-transfer-to-solvent states of aqueous ions probed using the core-hole-clock technique

Charge transfer between molecules lies at the heart of many chemical processes. Here, we focus on the ultrafast electron dynamics associated with the formation of charge-transfer-to-solvent (CTTS) states following X-ray absorption in aqueous solutions of Na+, Mg2+, and Al3+ ions. To explore the formation of such states in the aqueous phase, liquid-jet photoemission spectroscopy is employed. Using

The Use of Crowd Models for Risk Analysis During the Covid-19 Pandemic

The emergence of pandemics like Covid-19 has raised important issues regarding the safe utilisation of spaces due to the potential for virus transmission in both enclosed and open built environments. This chapter explores the challenges posed by pandemics in terms of safe space utilisation, considering the potential virus transmission risks. It presents a risk analysis methodology that makes use o