Identifying field management practices to promote crop production, while conserving soil health is essential to maintain long-term food production in a changing world. Also, providing experimental evidence to support the use of traditional agricultural practices is necessary to secure sustainable agriculture. Here, we conducted a long-term 12-year experiment to investigate the impact of different

Background and Objectives To determine how fully automated Elecsys CSF immunoassays for β-amyloid (Aβ) and tau biomarkers and an ultrasensitive Simoa assay for neurofilament light chain (NFL) correlate with neuropathologic changes of Alzheimer disease (AD) and frontotemporal lobar degeneration (FTLD). Methods We studied 101 patients with antemortem CSF and neuropathology data. CSF samples were col

BACKGROUND: Delaying cord clamping (CC) for 3-5 minutes reduces iron deficiency and improves neurodevelopment. Data on the effects of CC beyond 3 minutes in relation to short-term neonatal outcomes and maternal risk of postpartum hemorrhage are scarce.METHODS: This was a prospective observational study performed in two delivery departments. Pregnant women with vaginal deliveries were included. Tim

Recent studies have identified many potential climate change impacts on bridges. Considering the sheer number of these potential impacts, how can a bridge owner prioritise which impacts to consider, and for which bridges? This paper proposes a risk-based multi-criteria decision analysis method for systematically addressing these two questions simultaneously. The proposed method can be used to addr

The primary aim of this study was to determine whether an increase in DLQI score can predict an eczema flare up and thus a need for treatment escalation/physician appointment. The secondary aim was to explore variations in DLQI over time.

Large-eddy simulation (LES) of multiple-injection spray combustion under engine-like conditions is performed using a coupled model of an Eulerian stochastic field transported probability density function (ESF T-PDF) and a flamelet generated manifold (FGM). This coupled model allows the use of the T-PDF methods in modeling the interaction of turbulence and chemistry at affordable computational cost

Obesity, and obesity-associated conditions such as hypertension, chronic kidney disease, type 2 diabetes, and cardiovascular disease, are important risk factors for severe Coronavirus dis-ease-2019 (COVID-19). The common denominator is metaflammation, a portmanteau of metabolism and inflammation, which is characterized by chronically elevated levels of leptin and pro-inflam-matory cytokines. These

Background: Opioid overdose related injury or death can be prevented by bystander naloxone administration. For naloxone to be present when and where overdoses occur, opioid prevention education and naloxone distribution (OPEND) must be established on a broad level. This is the 30-month follow-up of the first multi-site naloxone project in Sweden, implemented at 31 sites in the County of Skåne 2018

Pregnancy, postpartum and menopause are regarded as periods women are more vulnerable to ischaemic events. There are conflicting results regarding stroke risk and hormone replacement therapy (HRT) during menopause. Stroke in pregnancy is generally increasing with serious consequences for mother and child; therefore, recommendations for acute treatment with intravenous thrombolysis (IVT) and/or mec

Objective: To compare the efficacy of angioplasty using drug-eluting balloons (DEB) compared with plain old balloon angioplasty (POBA) to reduce the rate of restenosis. Methods: This prospective, single-centre, single-blinded, 1:1 randomized, clinical trial enrolled patients that had primary or restenotic lesions in native upper extremity arteriovenous (AV) fistulas or at the graft-venous anastomo

Disability is frequently cited as a reason that Americans do not vote. This article offers legal and policy practitioner perspectives on core challenges people with disabilities face in exercising their voting rights in the United States, from obtaining election information to casting their ballots. Drawing on our collective experience-which includes professional experience as advocates working to

Background: Patients with chest pain may have normal coronary arteries and suffer from microvascular angina (MVA). The aim of this study was to determine if patients with suspected MVA have lower global myocardial perfusion (global MP) during adenosine stress compared with healthy controls and coronary artery disease (CAD) patients and to determine if there are sex differences in global MP. Method

Background: In hereditary angioedema (HAE), low levels (type 1) or defect in function (type 2) of the serine-protease inhibitor C1 Inhibitor protein results in activation of the classical pathway of the complement system as well as the contact system. Here, we investigated the risk of comorbidities in HAE. Methods: Individuals with HAE (n = 239; identified through a physician made diagnosis) and a

We have implemented and evaluated a secondary organic aerosol scheme within the chemistry transport model TM5-MP in this work. In earlier versions of TM5-MP the secondary organic aerosol (SOA) was emitted as Aitken-sized particle mass emulating the condensation. In the current scheme we simulate the formation of secondary organic aerosol from oxidation of isoprene and monoterpenes by ozone and hyd

We have used combined quantum mechanical and molecular mechanical (QM/MM) calculations to study the reaction mechanism of nitrogenase, assuming that none of the sulfide ligands dissociates. To avoid the problem that there is no consensus regarding the structure and protonation of the E4 state, we start from a state where N2 is bound to the cluster and is protonated to N2H2, after dissociation of H

Algal blooms constitute an emerging threat to global inland water quality, yet their spatial and temporal distribution at the global scale remains largely unknown. Here we establish a global bloom database, using 2.91 million Landsat satellite images from 1982 to 2019 to characterize algal blooms in 248,243 freshwater lakes, representing 57.1% of the global lake area. We show that 21,878 lakes (8.

The study of meaningful artifacts, such as pictures, has traditionally been caught between the humanities, which only take an interest in a selection of individual pictures, and psychology, which attends more to the majority reaction to pictures than to the nature of the pictures themselves. Some parts of semiotics, and, more, in particular, cognitive semiotics, endeavor to make use of all possibl

In recent years, social work with migrants and ethnic minorities has developed as a field of research and practice. Further, it is recognised in the literature that the increased processes of human mobility in today’s societies have driven a growing focus on inclusive cities, especially in larger urban areas where ethnic diversity and cultural heterogeneity can be found alongside newly arrived mig

Transitions to low-carbon energy technologies and other forms of climate mitigation tend to involve disempowerment and environmental injustices of various kinds. This paper argues that such tendencies are inherent in the social rationale of technological systems promoted by the logic of the world market. The production and operation of technological artifacts are imbued with economic rationality a