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Chemical labelling methods for gel free based proteomics

Popular Abstract in Swedish I den här avhandlingen behandlas olika aspekter av gelfria metoder för proteomanalys med masspektrometri, med tonvikt på inmärkningsmetoder. Arbetet är baserat på tre artiklar, där olika effekter vid inmärkning på peptider utreds, samt framtagningen av en ny typ av inmärkningsstrategi beskrivs. Kemisk inmärkning har haft stor betydelse för peptidbaserad proteomik eftersIn this thesis different aspects of gel free procedures for mass spectrometry based proteome analysis are addressed, with emphasis on labelling techniques. It is based on three original articles where the effects imposed onto peptides upon modification are investigated, and the development of a new type of labelling strategy is described. Chemical modification has been of great importance for the

Everyday working lives in a transnational corporation in Mexico: The contradictory cooptation of trade unionists

This article aims to contribute to the rich literature on neoliberalization and trade unions in Mexico by providing an examination of the contradictory relationships between capital, trade unions and the workers they represent, in a Swedish-based transnational corporation. The article investigates how the broader international relationships of dependency and exploitation are lived by workers and t

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Description of the history of research and the results of investigations of Sweden's only prehistoric flint mines at Södra Sallerup, southern Sweden.

Does landscape and habitat limit the frogs Rana arvalis and Rana temporaria in agricultural landscapes? A field experiment

Frogs are often rare or absent from intensively farmed areas. Here we explore the possibility that the landscape and the quality of the terrestrial habitat are unsuitable for these populations. Spawn of Rana arvalis and R. temporaria was introduced into ponds in a south Swedish agricultural landscape in 2003 (eight ponds) and 2004 (ten ponds). Metamorphs emerged from nine (R. a.) and 12 (R. t.) of

Framgångsrika organisationer

Ett flertal studier av svensk kommunal praktik pekar på betydelsen av att kommuner anpassar sig till förändrade förutsättningar (se till exempel Brorström och Siverbo 2008, Hellström med flera 2009). En del av dessa förändringar kan vara mer eller mindre tvingande, såsom förändringar i de lagar som omgärdar kommunal verksamhet, medan andra kan vara mer eller mindre frivilliga. Förändringar sker e

A collateral damage of international top-down approaches: parallel structures for disaster risk reduction and climate change adaptation in the SADC region

During the last decade, the interest of the international community in the concepts of disaster risk reduction and climate change adaptation has been growing immensely. Even though an increasing number of scholars seem to view these concepts as two sides of the same coin (at least when not considering potentially positive effects of climate change), in practice the two concepts have developed in p

Adsorption Properties of Triblock Copolymers at Solid Surfaces

The interfacial behaviour of nonionic triblock copolymers of the type poly(ethylene oxide-tetrahydrofurane-ethylene oxide) has been systematically examined at different types of surfaces. It is shown how the chemical nature of the substrate greatly influences the adsorption behaviour of block copolymers. Adsorption at hydrophilic surfaces resulted in the formation of micellar-like surface aggregat

Basic Concepts and Modelling Methods

Try to imagine a fire emergency evacuation. What is the first image that you have in your mind? Here there are some guesses. Probably a parent running inside a house trying to rescue her children, but not managing since she is too scared? An old man stuck crying in a corner of a room with flames and smoke all around him? Or a group of people crushing aggressively against each other in order to get

Kristen manlighet : ideal och verklighet 1830-1940

Från och med mitten av 1800-talet växte en tendens sig starkare att betrakta religion som något privat. Religionsutövning började sammankopplas med kvinnlighet och mjuka värden, och ansågs av somliga till och med som oförenlig med sann manlighet. Men var den verkligen det? Vilka uttryck tog sig den manliga religiositeten under en tid då kristendomen steg för steg förlorade sin tidigare ställning s

Oesophageal Resection with Gastric Tube Reconstruction - A clinical study of a surgical method and its consequences on the upper gastrointestinal tract and survival

Popular Abstract in Swedish Esofagektomi (kirurgiskt avlägsnande av matstrupen) är ett omfattande ingrepp som främst utförs pga cancer, men som även utförs vid vissa godartade sjukdomar. Matstrupen sträcker sig från svalget, via bakre delen av bröstkorgen ned till övre delen av buken. Det anatomiska läget gör att man ur kirurgisk synpunkt oftast måste avlägsna matstrupen via en kombination av inciIn a prospective randomised study following oesophagectomy and gastric tube reconstruction patients with hand-sutured neck anastomoses were compared with patients with circular stapled chest anastomoses. The two groups had equal rates of anastomotic or conduit leaks of 7.3 % (3/41) and 7.1 % (3/42) and of benign anastomotic strictures of 19.5 % (8/41) and 28.6 % (12/42). Another prospective random

Action, Politics and Human Rights

This chapter is a reflection on Kari Palonen's contributions to conceptual history, particularly his approach to the concept of "politics".

Enterostatin - target proteins and intracellular mechanisms. Function in food intake and energy metabolism

Popular Abstract in Swedish De flesta människor bibehåller en relativt konstant kroppsvikt genom livet trots att mängden mat och motion varierar från dag till dag. En konstant kroppsvikt betyder att energiintag (mat och dryck) och energiutgifter (värme och rörelse) i genomsnitt är lika stora, d.v.s. kroppens energibalans är i jämvikt. Övervikt är ett resultat av positiv energibalans, vilket innebäHunger and satiety are the results of complex neural events that involve several neurotransmitters and peptides. Enterostatin is an appetite-regulating peptide released in the intestine in response to fat ingestion. Enterostatin specifically decreases fat intake, but has also metabolic effects like inhibition of insulin secretion. Enterostatin has both central and gastrointestinal site of action,

On Self-adaptive Resource Allocation through Reinforcement Learning

Autonomic computing was proposed as a promising solution to overcome the complexity of modern systems, which is causing management operations to become increasingly difficult for human beings. This work proposes the Adaptation Manager, a comprehensive framework to implement autonomic managers capable of pursuing some of the objectives of autonomic computing (i.e., self-optimization and self-healin

Vetenskapligt tänkande : från kunskapsteori till metodteori

Det vetenskapliga arbetet och dess resultat blir alltmer betydelsefulla i det moderna samhället. Kraven som ställs på vetenskapliga undersökningar blir därmed högre. De som gör vetenskapliga undersökningar måste därför ha en större insikt i det vetenskapliga tänkande som ligger till grund för deras arbete. Denna bok visar på vilka kunskapsteoretiska och metafysiska grunder det vetenskapliga tänkan

Vilhelm Moberg tar ställning. En studie av hans journalistik och tidsaktuella diktning.

Popular Abstract in Swedish Journalistiken var genom alla år en vital del av Vilhelm Mobergs gärning, men den utgör en del av hans författarskap som inte tidigare ägnats en separat vetenskaplig studie. Avhandlingens syfte är att genom en studie av ett tidigare förbisett material bidra till att ge en fördjupad bild av ett centralt svenskt författarskap. Avhandlingen belyser Mobergs opinionsbildandeVilhelm Moberg (1898-1973) is one of the most well-known Swedish writers of the 20th century. In this dissertation attention is directed to his extensive journalism, a less well-known side of his authorship. The dissertation brings out and sheds light on a large number of his newspaper articles. An equally important part of his writing is his short controversial pamphlets. He also gave a large num