This study aimed to assess the costs and benefits of three alternative second-line treatment strategies for Swedish patients with type 2 diabetes mellitus (T2DM) who fail to reach glycated hemoglobin (HbA1c) ≤ 7% with metformin treatment alone: glucagon-like peptide-1 (GLP-1) receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, and neutral protamine Hagedorn (NPH) insulin.

The aim of this myocardial perfusion imaging (MPI) study was to compare the diagnostic performance of two computer-aided diagnosis (CAD) systems, EXINI Heart(TM) (EXINI), and PERFEXTM (PERFEX) Emory Cardiac Toolbox (ECT), and the summed stress score (SSS) values from both software packages. We studied 1,052 consecutive patients who underwent 2-day stress/rest Tc-99m-sestamibi MPI studies. The refe

There is growing evidence of the importance of extramatrical mycelium (EMM) of mycorrhizal fungi in carbon (C) cycling in ecosystems. However, our understanding has until recently been mainly based on laboratory experiments, and knowledge of such basic parameters as variations in mycelial production, standing biomass and turnover as well as the regulatory mechanisms behind such variations in fores

Cultivated fields and forests in South China are experiencing serious damage due to invasive alien plants. We investigated the relation between DNA C-values and invasiveness. The DNA C-values of 23 species ranged from 0.39 pg to 3.37 pg. Herbs, perennials and native species had higher mean DNA C-values than shrubs, annuals and invasive alien species. DNA C-values decreased with increasing invasive

Background: A beneficial role of fish consumption on the risk of myocardial infarction (MI) has been reported and is mostly ascribed to n-3 (omega-3) fatty acids. However, fish also contains methylmercury, which may increase the risk of MI. Objective: The objective was to determine how fish consumption and erythrocyte concentrations of mercury (Ery-Hg) and selenium (Ery-Se) are related to the risk

Background: Risk factors for rare gynecological cancers are largely unknown. Initial research has indicated that the metabolic syndrome (MetS) or individual components could play a role. Materials and methods: The Metabolic syndrome and Cancer project cohort includes 288 834 women. During an average follow-up of 11 years, 82 vulvar, 26 vaginal and 43 other rare gynecological cancers were identifie

Biodegradation of nonylphenol polyethoxylates (NPEO) has been studied in laboratory column bioreactors with a polyethylene carrier on which destructor bacteria of Pseudomonas surface-active compounds were immobilized. To monitor the efficiency of microbial treatment of model wastewater, a biosensor based on the oxygen Clark electrode and destructor bacteria of NPEO from bioreactors was designed. T

Mycorrhizal fungi constitute a considerable sink for carbon in most ecosystems. This carbon is used for building extensive mycelial networks in the soil as well as for metabolic activity related to nutrient uptake. A number of methods have been developed recently to quantify production, standing biomass and turnover of extramatrical mycorrhizal mycelia (EMM) in the field. These methods include min

Europrise is a Network of Excellence supported by the European Commission within the 6th Framework programme from 2007 to 2012. The Network has involved over 50 institutions from 13 European countries together with 3 industrial partners and 6 African countries. The Network encompasses an integrated program of research, training, dissemination and advocacy within the field of HIV vaccines and micro

Background Primary Sjogren's syndrome (pSS) is an autoimmune rheumatic disease mainly characterised by focal mononuclear cell infiltration in the salivary and lacrimal glands, and by the symptoms xerostomia and keratoconjunctivitis sicca. Germinal centre-like structures (GC) are found in the minor salivary glands of approximately 25% of patients. In this study, we aimed to assess genetic variation

Constructions of woven graph codes based on constituent convolutional codes are studied and examples of woven convolutional graph codes are presented. The existence of codes, satisfying the Costello lower bound on the free distance, within the random ensemble of woven graph codes based on s-partite, s-uniform hypergraphs, where s depends only on the code rate, is shown. Simulation results for Vite

Human beings make errors and that is nothing that we can avoid completely. We can however lower the risk of people doing wrong in situations where, for example, medical devices are used. The overall objective of the research presented in this paper is to investigate how usability testing can contribute to software risk management process in the medical device domain. Experience has been collected

Abstract Ph. D. Dissertation at Göteborg University Title: en todo caso, en cualquier caso, de todos modos, de todas maneras, de todas formas. Un estudio de las características y funciones de estas locuciones en el español contemporáneo. English title: en todo caso, en cualquier caso, de todos modos, de todas maneras, de todas formas. A study of the characteristics and functions of these expressio

This study addresses the timing and pressure-temperature (P-T) conditions of ophiolite obduction, one of the proposed causes of the ca. 470 Ma Grampian orogeny of Scotland and Ireland. This event gave rise to the main structural and metamorphic characteristics of the Grampian terrane-the type area for Barrovian metamorphism, the cause of which remains enigmatic despite a century of research. Zirco

This article explores the EU’s efforts to reunify and reconstruct Mostar through the seminal experiment of EUAM (1994-1996), which combined peacebuilding with urban reconstruction in an innovative way. The aim is to identify lessons to be learned from the experiences of EUAM that can assist the EU to adjust its peacebuilding approach to better address post-conflict divides in cities where the EU c

We have investigated the initial oxidation of the Rh(113) and Rh(223) vicinal surfaces by STM and ab initio simulations. Upon adsorption of small amounts of oxygen, the surface morphology is completely altered. Surprisingly, oxygen-stabilized Rh adatoms can be observed on the (113) facets, with oxide-like electronic properties. We present models of these "0D oxide" phases and discuss reasons for t

We present a method for determining a temperature differential across a quantum dot. If the device has a transmission function with sufficiently spaced resonant energies, then one can distinguish electrons which have tunneled from the hot lead, and those which have tunneled from the cold lead. By measuring the thermocurrent as the electrochemical potential is swept through a resonant energy level,