Reverse transcription-PCR (RT-PCR) assays have been used for analysis of circulating tumor cells (CTCs), but their clinical value has yet to be established. We assessed men with localized prostate cancer or castration-refractory prostate cancer (CRPC) for CTCs via real-time RT-PCR assays for KLK3 [kallikrein-related peptidase 3; i.e., prostate-specific antigen (PSA)] and KLK2 mRNAs. We also assess

Protein C inhibitor (PCI), a serine‐proteinase inhibitor first purified from human blood plasma, occurs at high concentrations (3–4 μM) in seminal fluid in both a high‐molecular‐mass and low‐molecular‐mass form. Immunochemical data have previously suggested that PCI in seminal plasma forms complexes with the most abundant serine proteinase in semen, prostate‐specific antigen (PSA). To provide a st

Most of the γglutamyltransferase occurring in semen was found to be bound to the membranes of prostatic organelles, as is the case with Mg+plus;-Ca+plus;-dependent ATPase, and Zn+plus;-dependent peptidase hydrolysing succinyl (alanine)3-paranitroanilide. Organelie-bound γglutamyltransferase was released in a water-soluble form by papain. Charge shift electrophoresis revealed the presence in semina

Coloniality persistently prevails in the many aspects of today’s societies, including identity constructions. However, the role of the Nordic region in colonialism and its continuous consequences has been severely downplayed, if not ignored, not least in connection to Finland. Thus, this research explores the visibilities of coloniality in social identity constructions in the context of Finland. A

Wireless power transfer is emerging into everyday life. The idea is to create a more convenient way of charging, or at least powering, devices. Ideally, all power transmitters and power-receiving devices should be interoperable so that the user does not need to investigate whether a specific power transmitter will work together with a specific device. Interoperability is what the standard Qi, inve

Due to the serious problem of greenhouse gas emissions in our atmosphere driving global warming, the need for sustainable initiatives has become an imperative for companies which leads to the necessity of operating sustainably. However, to avoid taking a weak approach to sustainability, it is imperative for companies to carry out a transition involving all three dimensions (environmental, economic

Denna kvalitativa intervjustudies syfte är att undersöka hur och om organisationer/företag motverkar diskriminering under rekryteringsprocessen. Detta gjordes genom att intervjua nio enskilda rekryterare inom, främst, konsult- och bemanningsbranschen. Genom intervjuerna fick jag ta del av deras rekryteringsprocesser och hur de arbetar med diskriminering Intervjuerna har analyserat genom en tolknin

The concept of measuring the proportions of various forms of PSA in serum, particularly the proportion of free to total PSA, represents a new and exciting method of detecting early curable prostate cancers and avoiding unnecessary prostate biopsies in men who have BPH only. Compared with other methods of improving diagnostic specificity, it does not require transrectal ultrasound for determination

Purpose – The purpose of this article is to investigate attempts to safeguard classical humanism in secondary schools by appealing to a cultural-historical link with Antiquity, voiced in the face of educational reforms in Sweden between 1865 and 1971.Design/methodology/approach – By focusing on the content of the pedagogical journal Pedagogisk Tidskrift, the article highlights a number of examples

Prostatic acid phosphatase (PAP), prostate‐specific antigen (PSA), and β‐microseminoprotein (β‐MSP) were regularly localized immunohistochemically to the epithelium of the acini and that of the ducts in the nodules of 24 cases of benign prostatic hyperplasia. The immunohistochemical distribution of these three prostatic‐secreted proteins was also examined, with monoclonal antisera against PAP and

A model is presented for studying the energy used by the braking system in heavy vehicles. The aim is to keep the model as simple as possible, while retaining reasonable fidelity for the problem at hand. All actuators are thus created as ideal, i.e. no losses, then simple dissipative loads are added where applicable in order to capture their effects from a vehicle systems perspective. The vehicle

Human prostate specific antigen, PSA, is a product of the human glandular kallikrein gene locus on chromosome 19 that is almost selectively expressed by prostate tissue. PSA is one of the dominating prostate derived proteins in seminal fluid. The mature form of PSA, a single chain glycoprotein of 237 amino acids, is a serine protease manifesting restricted chymotrypsin-like activity. PSA is mainly

ABSTRACT We studied patients and their relatives with partial deficiency, approximately 50% of normal plasma levels, of α1‐antichymotrypsin (ACT), an acute phase reactant with anti‐cathepsin G activity. Six of eight ACT deficient individuals, over 25 years of age, had liver and three of eight lung manifestations, varying from severe disease to subtle laboratory abnormalities. The ACT of deficient

Sammanfattning Titel: Samverkansstyrning i Safegrowthnätverket - En kvalitativ studie om samarbetsprocesser ur ett nätverksperspektiv. Syfte: Syftet med studien är att bidra med kunskap om hur kommuner kan utveckla och stärka de brottsförebyggande arbetet genom ett närmare samarbete med lokala invånare. Teoretiskt perspektiv: Studiens teoretiska ramverk har valts ut för att besvara studiens fr

Titel: Influerad av influencers. Universitet och program: Lunds Universitet, Campus Helsingborg. Service Management, Retail. Författare: Michaela Eliasson & Sandra Waldt Handledare: Åsa Friberg Problemområde: Under 2016 ägnade sig unga individer cirka sex timmar om dagen på sociala medier, däribland Instagram, som är en av de mest dominerande sociala medier-plattformarna. Sociala medier har

Objectives. Nearly half of men with clinically localized prostate cancer are understaged. We evaluated whether knowledge of preoperative free prostate-specific antigen (f-PSA), complexed (c-PSA), and total (t-PSA) concentrations or the ratios thereof (f-PSA/t-PSA, c-PSA/t PSA, and f PSA/c- PSA) could improve upon the staging of prostate cancer when compared with standard PSA testing (t-PSA). In ad

Sedimentary molybdenum (Mo) and uranium (U) enrichments are widely used to reconstruct changes in bottom water oxygen conditions in aquatic environments. Until now, most studies using Mo and U have focused on restricted suboxic-euxinic basins and continental margin oxygen minimum zones (OMZs), leaving mildly reducing and oxic (but eutrophic) coastal depositional environments vastly understudied. C