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Objectives: To evaluate whether long-term magnetic resonance imaging (MRI) findings, alone or in combination with prostate-specific antigen (PSA) density or the result of prior surveillance biopsies, could be used to omit biopsies occurring after patients have been on active surveillance (AS) for ≥5 years. Patients and Methods: Analysis of a single-institution AS cohort of patients with Grade Grou
The impact of obstructive sleep apnea (OSA) and positive airway pressure (PAP) treatment on COVID-19 severity is unclear. In this population-based, nationwide study using multi-register data, we aimed to assess if OSA is a risk factor for COVID-19 severity and how adherence to PAP treatment and clinical characteristics affect the risk. Swedish residents with COVID-19 infection January 2020–May 202
This research investigates the perceived barriers to UK Trade Unions (TU) engagement in climate change and environmental issues, from the perspective of union members working at local branch, union policy and strategy levels, and what opportunities there are for developing an environmental trade union movement. With the advent of catastrophic climate change necessitating rapid decarbonisation of t
Today, the overwhelming majority of Internet of Things (IoT) and mobile edge devices have extreme resource limitations, e.g., in terms of computing, memory, and energy. As a result, training Deep Neural Networks (DNNs) using the complex Backpropagation (BP) algorithm on such edge devices presents a major challenge. Forward-only algorithms have emerged as more computation- and memory-efficient alte
Being the premier forum for automotive user interface research and other vehicular technologies, AutomotiveUI concerns professionals, academics, researchers, and industry representatives from all around the world interested in innovation, research, and application of automotive user interface topics, embodying diversity at its core. This diversity is however not always reflected in the conference'
Simulating temporal changes in breast tissue has been challenging, despite advancement in virtual clinical trials. This study aims to enable virtual trials over time, motivated by interest in the effect of tissue involution on tumor visibility. We present a framework for creating 3D voxel-based breast phantoms and lesions using in-house Perlin Noise-based algorithm. The framework consists of three
: Based on the recent progress on research and development on automated vehicles, mass production of partially autonomous driving vehicles is expected to be available in the 2020s. According to the SAE standard level 3, a takeover situation may occur where the vehicle driving party changes if autonomous driving is released for unavoidable reasons resulting from vehicle or system limitations. In th
Background The fundamental problem with the pavement marking letter design is dealing with the phenomenon of image distortion by perspective. Because there has been a lack of a systematic way to deal with the problem on Korean pavement marking letters, the outputs have been determined by the installer's subjective design judgement. Ultimately, this causes low legibility. The purpose of this study
With the advancement in autonomous driving technology, the shape of vehicle seats is expected to change. Against this backdrop, a study is required to verify whether or not the diversely-changing seat arrangements are appropriate from the emotional perspective of the driver. This study set the first-row passenger scat with an adjustable seatback, such as an upright position, a 15-degree rotation,
The water level-area-storage volume (Z-A-V) relationship serves as the cornerstone of reservoir operations, governing water allocation, flood mitigation, and power generation. Sedimentation-induced capacity alterations can progressively degrade Z-A-V accuracy, yet systematic curve updates remain inadequately implemented across developing nations. Traditional reconstruction approaches face inherent
To reduce traffic accidents caused by driver factors, realizing technology to monitor and preemptively respond to the state of a driver is necessary. In this study, drivers' electroencephalogram (EEG) data during driving were acquired, and the effect of carelessness warnings was analyzed. The frequency of carelessness per minute was low for the case of presence of warnings. The originality of this
Due to the rapid climate change, drivers are now more likely to drive in severe weather conditions than before. In bad weather, drivers have no option but to cope with a very unusual environment, increasing the likelihood that an accident will transpire. Therefore, it is important to find ways to operate vehicle systems more easily and safely during bad weather. In this study, we investigated 6 in
This study explores the exchange of cultural information that takes place in the meeting between immigrant and non-immigrant characters in a selection of Australian novels focusing on the theme of migration: Heartland (1989) by Angelika Fremd, A Change of Skies (1991) by Yasmine Gooneratne, Stella’s Place (1998) by Jim Sakkas, Hiam (1998) by Eva Sallis and Love and Vertigo (2000) by Hsu-Ming Teo.
This invention is directed to a method for the preparation of docetaxel having an amorphous, anhydrous crystalline, or hydrated crystalline structure. In accordance with the invention, highly pure amorphous, anhydrous crystalline, or hydrated crystalline docetaxel can be produced with a high yield by using a solvent precipitation method, colloid formation method, etc.
Provided is a method for preparing a taxane derivative, comprising: carrying out condensation of a phenylisoserine derivatives having a protective group introduced thereto or a mixture of isomers thereof, as a side chain, with a baccatin III derivative or 10-deacetyl-baccatin III derivative to obtain a mixture of isomers; separating the isomers via chromatography; and carrying out a reversion of t
This invention is directed to a method for efficiently separating and purifying 13-dehydroxybaccatin III and 10-deacetylpaclitaxel with a high purity of 90% or higher purity, preferably 99.5% or higher purity, from taxane-containing materials such as Taxus species, and the thusly obtained highly pure 13-dehydroxybaccatin III and 10-deacetylpaclitaxel can be used as semi-synthetic precursors of pac
I denna avhandling undersöktes exekutiva funktioner (EF) hos svenska barn och ungdomar. EF definierades som en uppsättning neurokognitiva processer som reglerar kognitiva, emotionella och beteendemässiga aktiviteter, viktiga för målinriktat handlande. EF bedömdes med hjälp av själv-, föräldra- och lärarskattningar av den första och andra upplagan av Behavior Rating Inventory of Executive Function This thesis examines executive functioning (EF) among Swedish youth. EF is defined as a set of neurocognitive processes regulating cognitive, emotional, and behavioral activities essential for goal-directed behavior. I assessed EF using the self-, parent-, and teacher-report forms from the original and second editions of the Behavior Rating Inventory of Executive Function (BRIEF and BRIEF2). A pri
The present invention relates to a method of removing an endotoxin from solution containing basic proteins. More specifically, the method of the present invention comprises the steps of adding the surfactant to solution containing the basic protein obtained from the recombinant microorganism and mixing the resultant, of loading the resultant solution on the cation exchange column, washing the cati
Through the analysis of the case of the Age of Empires IV community, this qualitative study investigates how the communal efforts of the audience can foster inclusivity, and the meaningful participation of women, in the context of contemporary video game play. Through the analysis of nine semi-structured qualitative interviews, this paper reconstructs the ‘Age of Empires IV tale’: as it evolved fr
