Dissociation of vasomotor and metabolic responses to levodopa has been observed in human subjects with Parkinson's disease (PD) studied with PET and in autoradiograms from 6-hydroxydopamine (6-OHDA) rat. In both species, acute levodopa administration was associated with increases in basal ganglia cerebral blood flow (CBF) with concurrent reductions in cerebral metabolic rate (CMR) for glucose in t

Indoor lighting is facing a massive retrofit to LED lighting. Research is needed to assess whether LED-based lighting can promote energy efficiency, boost visual comfort and support biological functions. This field study considered the lighting of four identical classrooms in an upper secondary school in Helsingborg, Sweden. Two classrooms were fitted with state-of-the-art ceiling pendants contain

Epigenetic variation in human adipose tissue has been linked to type 2 diabetes and its related risk factors including age and obesity. Insulin resistance, a key risk factor for type 2 diabetes, may also be associated with altered DNA methylation in visceral and subcutaneous adipose tissue. Furthermore, linking epigenetic variation in target tissues to similar changes in blood cells may identify n

The computation power we expect from the various smart devices we use keeps increasing. Not only do we want faster devices but also less power hungry and energy efficient devices, both for the environment and our personal convenience (remember that "mobile phone" attached to a power plug at all times?).One way of addressing this demand is to build custom processor architectures that focus on a spe

The aim of this study was to investigate whether various dimensions of student–teacher relationships were associated with different types of motivation to defend victims in bullying and to determine the association between these types of motivations and various bystander behaviors in bullying situations among early adolescents in Italy. Data were collected from 405 Italian adolescents who complete

Denna avhandling behandlar två essentiella ting, vatten som är grundläggande för allt liv på jorden och kväve, vilket är ett grundämne som återfinns i varje protein och DNA. Liksom allt annat, måste dessa ämnen hålla en lagom nivå i cellen. För att klara variationer i tillgänglighet av dessa ämnen, har alla livsformer hittat sätt att påverka upptag och frisättning av dem. För att realisera detta pMajor intrinsic proteins, also referred to as aquaporins (AQPs) are localized in membranes of all domains of life to increase the permeability to water or other small, polar molecules. Several monophyletic groups can be discerned in this large and divergent protein superfamily. Members within these subfamilies commonly show a similar substrate selectivity established by conserved filters. Comparis

This paper continues the discussion in a previous paper [Saeidpour and Wadsö doi:10.1016/j.cemconres.2016.02.003] where a clear effect of sorption hysteresis was seen in moisture diffusion coefficients for cement-based materials. Coefficients with vapor content as potential (Dv) had different values depending on whether the sample was in absorption or in desorption. In this paper we recalculate th

Plant litter represents an important source of nutrients and energy for soil microorganisms, but will also selectively affect which organism group, fungi or bacteria, that will be favoured during decomposition. The balance of fungal to bacterial growth will furthermore be affected by soil chemistry like pH. A laboratory experiment was carried out using two different Mediterranean forest soils diff

Rodent models of L-DOPA-induced dyskinesia (LID) are essential to investigate pathophysiological mechanisms and treatment options. Ratings of abnormal involuntary movements (AIMs) are used to capture both qualitative and quantitative features of dyskinetic behaviors. Thus far, validated rating scales for the mouse have anchored the definition of severity to the time during which AIMs are present.

Cranial radiotherapy is a known risk factor for neurocognitive impairment in survivors of childhood acute lymphoblastic leukemia (ALL). Understanding the nature of cognitive dysfunction during adulthood in ALL survivors is important as it has an impact on major life situations. Thirty-eight (21 women) ALL survivors were investigated 34 years after diagnosis. Median-age was 38 (27–46) years. All we

The screenplay written by Italian screenwriter and film director Massimo Franciosa in 1995 andfreely based on the short story Checchina’s virtue (1884) by Italian novelist and journalist MatildeSerao (1856-1927) is an example of those submedia ”designed especially to be transmediated”,according to Elleström (2014, 26). The transmediation never occurred however, since the filmnever came into being,

Cultural and creative activities are today described as central to regional and urban development by politicians and governments. Creative city policies are often aiming at economic benefits for the city itself, and there are normative purposes with many research studies as well as projects undertaken (Eckardt 2005; Markusen and Gadwa 2010; Kovacs 2011). Creative city policy is often oriented towa

Recognition and removal of apoptotic and necrotic cells must be efficient and highly controlled to avoid excessive inflammation and autoimmune responses to self. The complement system, a crucial part of innate immunity, plays an important role in this process. Thus, apoptotic and necrotic cells are recognized by complement initiators such as C1q, mannose binding lectin, ficolins, and properdin. Th

Africa has been undergoing significant changes in climate and vegetation in recent decades, and continued changes may be expected over this century. Vegetation cover and composition impose important influences on the regional climate in Africa. Climate-driven changes in vegetation structure and the distribution of forests versus savannah and grassland may feed back to climate via shifts in the sur

This article focuses on coordination between governance actors in a public university. The purpose of this paper is to illustrate and analyze policy documents as governance tools that allow departmental management to coordinate with the authorities, the board, and the management at different university levels. A central finding is that the importance of policy documents as governance tools takes e

In this study the effect of the application of pulsed electric fields as pre-treatment before air drying of basil leaves at 50 °C was investigated. The parameters of the electric treatment were designed in such a way that they either (i) electroporated the tissue reversibly (tissue remains viable) and without electroporating the guard cells in the stomata complex (65 pulses of 600 V/cm, 120 μs pul

Mathematical optimization is becoming increasingly important for engineering in general and control in particular. This thesis deals with numerical methods, primarily direct collocation, and symbolic methods, primarily block-triangular ordering and tearing, for numerical solution of general dynamic optimization problems involving dynamical systems modeled by large-scale differential-algebraic equa