Model-based Approaches to Diffuse Optical Imaging and Dosimetry
The work within this thesis investigates Photodynamic therapy and Fluorescence imaging for therapeutics and visualization of deeply embedded lesions. Photodynamic therapy (PDT) is a cancer treatment modality that can eradicate tumors when light, a photosensible drug and oxygen are present. In recent decades there has been an interest in adapting this modality to deep-seated solid tumors. This req