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Imagining the Digital Society – Metaphors from the Past and Present

This primer introduces a series of essays on the politics of metaphors in the digital society. It aims to uncover the hidden assumptions and concepts within our discourses of the digital, piece by piece.The current rapid social and technological change is giving rise to enormousuncertainties – and a great need for explanation and sense-making. How do weunderstand the digital society? When we talk about the future that we cannot knowand a present that we do not understand, we have no option but to use the conceptual apparatus of the past – with normative, social and economic implications. This pri

The epigenesis of meaning in human beings, and possibly in robots

This article addresses a classical question: Can a machine use language meaningfully and if so, how can this be achieved? The first part of the paper is mainly philosophical. Since meaning implies intentionality on the part of the language user, artificial systems which obviously lack intentionality will be `meaningless' (pace e.g. Dennett). There is, however, no good reason to assume that intenti

Political Power of Photography: The Materiality of 14 and 6 October

This paper presents a study of the role that photography of 14 October 1973 and 6 October 1976 has played in political mobilization around the two events. It is well known that in official archives limited versions of the events can be found. We must turn to alternative repositories (private homes, non­states organisations, but also universities and libraries outside of Thailand) to find the antic

Europe's lost forests : A pollen-based synthesis for the last 11,000 years

8000 years ago, prior to Neolithic agriculture, Europe was mostly a wooded continent. Since then, its forest cover has been progressively fragmented, so that today it covers less than half of Europe's land area, in many cases having been cleared to make way for fields and pasture-land. Establishing the origin of Europe's current, more open land-cover mosaic requires a long-term perspective, for wh

Astrocytic and neuronal oxidative metabolism are coupled to the rate of glutamate–glutamine cycle in the tree shrew visual cortex

Astrocytes play an important role in glutamatergic neurotransmission, namely by clearing synaptic glutamate and converting it into glutamine that is transferred back to neurons. The rate of this glutamate–glutamine cycle (VNT) has been proposed to couple to that of glucose utilization and of neuronal tricarboxylic acid (TCA) cycle. In this study, we tested the hypothesis that glutamatergic neurotr

A field guide for cancer diagnostics using cell-free DNA : From principles to practice and clinical applications

Recently, many genome-wide profiling studies provided insights into the molecular make-up of major cancer types. The deeper understanding of these genetic alterations and their functional consequences led to the discovery of novel therapeutic opportunities improving clinical management of cancer patients. While tissue-based molecular patient stratification is the gold standard for precision medici

A multi-level model correlation approach for low-frequency vibration transmission in wood structures

The main challenge in predicting structure-borne sound in wood buildings is to accurately model the vibration transmission between the source and the receiving room. Large variations in model parameters make it difficult to predict absolute vibration levels and to make conclusions regarding the relative effects of different designs. A step towards establishing reliable models is to investigate the

Constraining the magnitude of the Chiral Magnetic Effect with Event Shape Engineering in Pb–Pb collisions at sNN=2.76 TeV

In ultrarelativistic heavy-ion collisions, the event-by-event variation of the elliptic flow v2 reflects fluctuations in the shape of the initial state of the system. This allows to select events with the same centrality but different initial geometry. This selection technique, Event Shape Engineering, has been used in the analysis of charge-dependent two- and three-particle correlations in Pb–Pb