This paper describes a numerical analysis of a heat transfer enhancement technique that introduces fractal-shaped design for impingement cooling. Based on the gas turbine combustion chamber cooling, a fractal-shaped nozzle is designed for the constant flow area in a single impingement cooling model. The incompressible Reynolds-averaged Navier-Stokes equations are applied to the system using CFD so

Measurements of differential cross-sections of top-quark pair production in fiducial phase-spaces are presented as a function of top-quark and tt¯ system kinematic observables in proton-proton collisions at a centre-of-mass energy of s=13 TeV. The data set corresponds to an integrated luminosity of 3.2 fb−1, recorded in 2015 with the ATLAS detector at the CERN Large Hadron Collider. Events with ex

Large-scale chromosomal rearrangements are an important source of evolutionary novelty that may have reshaped the genomes of existing yeast species. They dramatically alter genome organization and gene expression fueling a phenotypic leap in response to environmental constraints. Although the emergence of such signatures of genetic diversity is thought to be associated with human exploitation of y

BACKGROUND: Osteoporosis and fracture risk are considered to be under genetic control. Extensive work is being performed to identify the exact genetic variants that determine this risk. Previous work has suggested that a G/T polymorphism affecting an Sp1 binding site in the COLIA1 gene is a genetic marker for low bone mineral density (BMD) and osteoporotic fracture, but there have been no very-lar

Peak bone mass is an important risk factor for the development of osteoporosis in later life. Previous work has suggested that genetic, intrauterine, and environmental factors all contribute to the regulation of bone mass, but the ways in which they interact with each other to do so remain poorly understood. In this study, we investigated the relationship between peak bone mass and polymorphisms o

Genetic factors play an important role in the pathogenesis of osteoporosis by affecting bone mineral density and other predictors of osteoporotic fracture risk such as ultrasound properties of bone and skeletal geometry. We previously identified a polymorphism of a Sp1 binding site in the Collagen Type 1 Alpha 1 gene (COLIA1) that has been associated with reduced BMD and an increased risk of osteo

UNLABELLED: The VDR is a candidate gene for osteoporosis. Here we studied five common polymorphisms of VDR in relation to calcium intake and vitamin D status in a population-based cohort of 3100 British women, but found no significant association with bone mass, bone loss, or fracture.INTRODUCTION: Population studies of vitamin D receptor (VDR) polymorphisms have produced conflicting results. We p

Signal apparition is a method for encoding sources in simultaneous multisource seismic acquisition and decoding the multisource response of the earth into its single-source responses. For M sources, encoding is performed by applying periodic sequences of period M to each of the sources along source lines. Decoding is achieved in the wavenumber domain for each frequency by solving an M × M linear s

Total internal reflection fluorescence (TIRF) microscopy is a powerful method that allows examination of plasma membrane close events in real time. The last decade, the method has successfully been used to explore GLUT4 translocation in adipocytes. Here, we describe the procedure for studying GLUT4 trafficking using TIRF microscopy in isolated primary adipocytes.

Little is known about the development of vision in wild birds. It is unknown, for example, whether the ability to see can be predicted by the level of prenatal growth or whether the eyes are open at hatching in a particular species. In this study, we investigated the growth of eyes, the formation of retinal ganglion cell topography, and the appearance of simple, visually guided behaviours in chick

The Circular Economy (CE) gained significant traction in business and academia. While in the building sector issues around energy efficiency are being widely explored, CE is still a relatively new topic. This article reports on three CE pilots in the Dutch building sector and develops a collaboration tool for developing and operating circular buildings and their supply chain collaborations. First,

Objective: To investigate associations between neonatal delivery weight and future risk of maternal type 1 or type 2 diabetes. Methods: Data included in the Swedish Medical Birth Registry and Swedish National Diabetes Registry were merged to include all women born during 1930–1989; patients with pre-existing diabetes or gestational diabetes were excluded. Cox regression analyses were performed to

Objective: There is a decreased risk of breast cancer in systemic lupus erythematosus (SLE) versus the general population; little is known regarding the receptor status of breast cancers in SLE, or treatment. Methods: Breast cancer cases occurring after SLE diagnosis were ascertained through linkage with tumor registries. We determined breast cancer positivity for estrogen receptors (ER), progeste

Kan man sätta betyg på retorik? Vad är det i så fall man betygsätter - sin egen eller en tänkt mottagares upplevelse? Och gör det retorikstuderande till bättre retorikeroch/eller duktigare retorikstuderande att de får betyg? Sara Santesson reflekterar kring hur man bäst skapar grogrund för studenter som vill utvecklas som retoriker.