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Experimental and Clinical Studies on Contact Allergy to Diphenylmethane-4,4′-diisocyanate and Related Substances

The exposure to isocyanates is more of an occupational problem than a consumer problem. The main route of exposure is assumed to be through inhalation. Isocyanates that have high vapor pressure, such as TDI, can be airborne at room temperature. Other isocyanates such as MDI are volatile only when heated. Industrial processes that can cause exposure to isocyanates are, for example, spraying or heat

What is value and how is it managed?

The meaning of the notion of value, as well as associated concepts such as value creation and value appropriation, has been subject to much confusion in marketing and management.This article builds on a rich tradition in economics to untangle some of the ambiguities surrounding these concepts. First, it is argued that a rigorous approach to analyzing value must be based on a subjectivist notion of

Naturalistic studies - Researching the everyday clinical world

During the last decade, a vast amount of research has been produced concerning the efficacy of different pharmacological and psychological treatments in psychiatry for various diagnoses. This movement towards evidence-based practices has aimed at grounding clinical practice in evidence derived from research, to optimize outcomes. Such developments should translate into the successful management of

Do humans really prefer semi-open natural landscapes? A cross-cultural reappraisal

There is an assumption in current landscape preference theory of universal consensus in human preferences for moderate to high openness in a natural landscape. This premise is largely based on empirical studies of urban Western populations. Here we examine for the first time landscape preference across a number of geographically, ecologically and culturally diverse indigenous populations. Included

Applying circular economy principles to building materials : Front-running companies’ business model innovation in the value chain for buildings

To meet the United Nations Sustainable Development Goals (SDG) on sustainable production and consumption (goal 12), the construction sector should be considered a key area to improve efficient use of natural resources (goal 12.2) and reduce waste generation (goal 12.5). With buildings being more energy efficient during their use phase, the relative importance of embodied energy and natural resourc

Planners’ analysis and opportunism – benefit analysis in the Swedish HSR-project : a preliminary analysis

The dominating form of analysis in the transport sector is cost–benefit analysis (CBA). This study investigates the purpose and use of an alternative analysis intended to complement CBA in the Swedish high-speed rail project. According to CBA calculations, the project is heavily unprofitable. While some politicians called for project termination, the project leadership launched an alternative bene

What about the boards? : Issues of transparency and accountability in board composition

Sweden is generally regarded as a country with little corruption, equal rights for men and women and a strong emphasis on democratic values. Still, the appointment of political representatives to the boards of municipal corporations occurs without consideration of these values. One step towards increasing our knowledge about the governance of municipal corporations in Sweden is to look at how curr

The impact study - Motivating a change in health behaviour

IMPaCT is a five-year project funded by the Department of Health, UK. Running in the UK and now Sweden, the IMPACT Project aims to target the poor physical health and excessive substance use seen in people with SMI. There is evidence that behavioural interventions may be associated with an improvement in physical health and substance use in this population. IMPaCT is a randomised controlled trial

Unstable low-mass planetary systems as drivers of white dwarf pollution

At least 25 percent of white dwarfs show atmospheric pollution by metals, sometimes accompanied by detectable circumstellar dust/gas discs or (in the case of WD 1145+017) transiting disintegrating asteroids. Delivery of planetesimals to the white dwarf by orbiting planets is a leading candidate to explain these phenomena. Here, we study systems of planets and planetesimals undergoing planet–planet

Low expression of hexokinase-2 is associated with false-negative FDG–positron emission tomography in multiple myeloma

18F-Fluorodeoxyglucose (FDG)–positron emission tomography (PET) and diffusion-weighted magnetic resonance imaging with background signal suppression (DWIBS) are 2 powerful functional imaging modalities in the evaluation of malignant plasma cell (PC) disease multiple myeloma (MM). Preliminary observations have suggested that MM patients with extensive disease according to DWIBS may be reported as

The welfare state that wanted to keep track of its citizens : Personal identity numbers as administrative technology

The development of the Swedish welfare state is often characterized by several comprehensive social reforms and organizational changes. In previous research, as in the previous chapters of this book, scholars often tend to direct their interest towards these reforms. Often left out are the tacit administrative technological infrastructures that enabled these. The Swedish social security number, th

Techno-economic evaluation of biogas upgrading using ionic liquids in comparison with industrially used technology in Scandinavian anaerobic digestion plants

The process of biogas upgrading with ionic liquids, i.e. pure 1-butyl-3-methylimidazolium bis(trifluoro-methylsulfonyl)imide ([bmim][Tf2N]), aqueous choline chloride/urea (ChCl/Urea), and aqueous 1-allyl-3-methyl imidazole formate ([Amim][HCOO]), was simulated in Aspen Plus and compared with the conventional water scrubbing upgrading technique. The comparisons of the performances on the amount of

Improving patient-assessed outcomes after cataract surgery

Purpose: To identify and evaluate possible causes of poor patient-reported visual function after cataract surgery. Methods: We obtained retrospective data from the Swedish National Cataract Register on patient self-assessed visual function before and after cataract surgery based on the Catquest-9SF questionnaire. We identified patients who self-reported similar or more difficulties postoperatively

Differences in cardiac disease prevalence and in blood variables between major and minor stroke patients

In 310 patients with carotid territory stroke, we investigated whether a history of cardiac disease was more frequent among those with major stroke (n = 169) than among those with minor stroke (n = 141), and whether the two groups differed in values for blood variables directly or indirectly associated with stroke, each variable being adjusted for age and sex. A history of angina pectoris was more

No improvement in injection frequency or in visual outcome over time in two cohorts of patients from the same swedish county treated for wet age-related macular degeneration

Background: Although ranibizumab has been used for the treatment of wet age-related macular degeneration (AMD) since 2007, real-world studies still report undertreatment resulting in a less favorable visual outcome. In this study, two different time cohorts of patients treated with ranibizumab for wet AMD in routine care were analyzed to observe whether there was a change over time regarding visua

No title

This study attempted to give a vision through which we can analyze narrative texts in artistic way bearing in mind their internal production conditions in addition to transformation trait which is related existentially to textual transformation. This is why it is called so. Thus textual transformation includes smaller transformations starting from the surface structure of the text, the place, the

Development of novel therapies for Diamond-Blackfan Anemia

Diamond-Blackfan anemia is a congenital erythroid hypoplasia manifesting early inlife. In at least 60-70% of cases, DBA is caused by a functional haploinsufficiencyof genes encoding for ribosomal proteins. Approximately, 25% percent of patientshave mutations in the gene encoding ribosomal protein S19 (RPS19). Thehematological profile of DBA patients shows macrocytic anemia withreticulocytopenia, n