Background: Large animal models are important in atrial fibrillation (AF) research, as they can be used to study the pathophysiology of AF and new therapeutic approaches. Unlike other animal models, horses spontaneously develop AF and could therefore serve as a bona fide model in AF research. We therefore aimed to study the electrical, functional and structural remodelling caused by chronic AF in

Human herpesvirus (HHV)-6A or HHV-6B involvement in multiple sclerosis (MS) etiology has remained controversial mainly due to the lack of serological methods that can distinguish the two viruses. A novel multiplex serological assay measuring IgG reactivity against the immediate-early protein 1 from HHV-6A (IE1A) and HHV-6B (IE1B) was used in a MS cohort (8,742 persons with MS and 7,215 matched con

Glycerol levels in adipocytes depend on the lipolysis, the hydrolysis of triglycerides into glycerol and free fatty acids, and the efflux of glycerol across the plasma membrane through glycerol channels. The aims of this work were to investigate how glycerol levels are regulated on a molecular level by PLIN1, a major lipid droplet-associated protein and a key regulator of the lipolysis by scaffold

Climate change shocks and stresses are expected to increasingly affect urban areas in Sub-Sahara Africa (SSA). However, there remain gaps in understanding local precipitation extremes and influential factors that can enhance urban resilience. This study synthesized determinants of urban resilience, investigated historic and projected precipitation extremes up to the year 2050. Also assessed were f

I ett Europa där gränskontroller intensifieras och deportationer ökar ställer denna avhandling frågor om möjligheter till motstånd och aktivism genom teater. Den tar sin utgångspunkt i en deltagande etnografisk undersökning av No Border Musical. No Border Musical skapades och sattes upp i Malmö under 2011–2013. Initiativet togs av personer kopplade till den lokala flyktingrättsrörelsen. Ungefär häIn a context of deportability and bordering practices, this thesis asks questions regarding possibilities and limitations of resistance through community theatre. It sets out from a participatory ethnographic exploration of the working process and performance of the No Border Musical. The No Border Musical was created in 2011–2013 in the city of Malmö in southern Sweden. It was initiated by people

The arctic tern Sterna paradisaea completes the longest known annual return migration on Earth, traveling between breeding sites in the northern arctic and temperate regions and survival/molt areas in the Antarctic pack-ice zone. Salomonsen (1967, Biologiske Meddelelser, Copenhagen Danske Videnskabernes Selskab, 24, 1) put forward a hypothetical comprehensive interpretation of this global migratio

A numerical study was conducted to investigate the mechanism of laminar flow and heat transfer enhancement in an interrupted microchannel heat sink (IMCHS) with different shaped ribs at Reynolds number ranging from 100 to 900. The global flow features, heat transfer and friction for IMCHS with no ribs, rectangle ribs, triangle ribs and trapezoid ribs are detailed compared. The results show that th

The wear of metal cutting tools is known to take place by the combined and simultaneous effects of several wear mechanisms. Knowledge of the relative contribution of the individual wear mechanisms is required to understand and predict the tool wear during cutting different workpiece materials and alloys. It has been shown previously that machining two heat resistant superalloys, alloy 718 and Wasp

Background: Organ involvement often occurs in early systemic sclerosis and has been related to premature death. Identifying patients at diagnosis at risk of developing early organ involvement would be useful to optimize screening and management strategies. Objective: To develop prediction models for the 5-year development of interstitial lung disease, pulmonary arterial hypertension and death. Met

Pavement data collection is the most expensive and time consuming component of Pavement Management System (PMS). Thus, possible methods of minimizing the need of such data might be critical in reducing pavement condition monitoring costs. Also the ability to relate pavement performance prediction models (frequently roughness based) to hot mix asphalt field performance models (distress based) provi

Randomized clinical trials are the preferred study design to address key research questions about the benefits or harms of interventions. However, randomized trials of oxygen therapy are difficult to conduct and have limitations. The purpose of this article is to offer our view on the potential use of patient registries in the field of home oxygen in COPD as an alternative to randomized trials by

Purpose: Traumatic brain injury causes morbidity and mortality worldwide. S100B is the most documented emergency brain biomarker and its urine-assay might be advantageous because of easier sampling. The primary aim was to evaluate urine S100B’s ability to rule out intracranial hemorrhage. Secondary aims included S100B temporal pattern for 48 h post-trauma and chemical properties of urine that affe

Introduction Intimate partner violence (IPV) is regarded an important public health and human rights issue, characterized by physical, sexual or emotional abuse. Globally more than one in three women report physical or sexual violence by their intimate partners. Though the association between IPV and depression is known, we found no study investigating depression as a risk factor for IPV and very

The standard way today to obtain measures of inflationary expectations is to use questionnaires to ask a representative group of respondents about their beliefs of the future rate of inflation during the coming 12 months. This type of data on inflationary expectations as well as on inflationary perceptions has been collected in a unified way on an EU-wide basis for several years. By now, probably

Crop residues and manure are important sources of carbon (C) for soil organic matter (SOM) formation. Crop residue return increases by nitrogen (N) fertilization because of higher plant productivity, but this often results only in minor increases of SOM. In our study, we show how N fertilization and organic C additions affected SOM and its fractions within a 32-year-long field-experiment at Puch,