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No adverse events after simultaneous administration of 50 000 IU vitamin A and Bacille Calmette-Guerin vaccination to normal-birth-weight newborns in Guinea-Bissau

Objective:To determine whether the combined intervention of 50 000 IU vitamin A administered together with Bacille Calmette-Guerin (BCG) vaccination at birth was associated with adverse events, in particular bulging fontanels and adverse reactions to BCG.Subjects/Methods:From an ongoing trial, 2145 infants randomized to 50 000 IU vitamin A or placebo with BCG vaccination were recruited. Adverse ev

Enzyme activities in the tibialis anterior muscle of young moderately active men and women: relationship with body composition, muscle cross-sectional area and fibre type composition.

The aims of this study were (i) to assess the differences between men and women in maximal activities of selected enzymes of aerobic and anaerobic pathways involved in skeletal muscle energy production, and (ii) to assess the relationships between maximal enzyme activities, body composition, muscle cross-sectional area (CSA) and fibre type composition. Muscle biopsies were obtained from the tibial

Prediction of relative glomerular filtration rate in adults: New improved equations based on Swedish Caucasians and standardized plasma-creatinine assays.

OBJECTIVE: To evaluate newly developed equations predicting relative glomerular filtration rate(GFR) in adult Swedish Caucasians and to compare with the Modification of Diet in Renal Disease(MDRD) and Mayo Clinic equations using enzymatic and zero-calibrated plasma creatinine assays. MATERIAL AND METHODS: GFR was measured with iohexol clearance adjusted to 1.73 m(2). One population sample (n=436/L

Från Eden till Damavdelningen : studier om kvinnan i litteraturen : en vänbok till Christina Sjöblad

Under den vida rubriken Från Eden till Damavdelningen har uppsatser om kvinnan som författare, som huvudkaraktär, som objekt, som samhällshot, som mor och maka, som ung flicka, som offer, som bohem, som resenär och som naturskildrare samlats. Variationerna av uppsatsernas innehåll är stora. Som titeln antyder sträcker sig ämnena tidsmässigt från den paradisiska till den moderna tiden. Med boken vi

Fakiren på film

Om filmatiseringen av Axel Wallengrens (Falstaff, fakirs) novell "Ett svårskött pastorat" (1958).

Att välja döden

Översiktligt om självmord i historiskt perspektiv, lagstiftning, källkritiska problem, litteraturtips.

Intrapatient evolution of HIV-1 in the context of coreceptor usage

The variable region 1 to 3 (V1-V3) of the HIV-1 envelope plays an important role in coreceptor usage. Early in infection HIV- 1 is using CCR5 as coreceptor to enter target cells (R5 viruses) whereas viruses using CXCR4 as coreceptor (X4 viruses) may appear later in infection. This broadening or switch in coreceptor usage is associated with progression to AIDS. In my thesis work, we have compared t

Quantum chemical geometry optimizations in proteins using crystallographic raw data.

A method is developed for the combination of quantum chemical geometry optimizations and crystallographic structure refinement. The method is implemented by integrating the quantum chemical software Turbomole with the crystallographic software Crystallography and NMR System (CNS), using three small procedures transferring information between the two programs. The program (COMQUM-X)is used to study

Nutrition in acute pancreatitis - influence on gut barrier and inflammatory response

Popular Abstract in Swedish Den övergripande målsättningen för projektet var att studera nuvarande vätske- och nutritionsbehandling samt effekter av tidigt insatt sondnäring och tidigt insatt normal kost vid akut bukspottkörtelinflammation (pankreatit). Företeelser som särskilt studerades var akut inflammatoriskt svar, tarmbarriär och kliniskt förlopp. Bakgrund Akut pankreatit (AP) drabbar ca 30Acute pancreatitis (AP) is associated with metabolic changes, acute inflammatory response and increased gut permeability. In AP, traditional treatment has been initial fasting on purpose to avoid activation of proteolytic enzymes and pancreatic enzyme secretion. However, enteral feeding has been suggested superior to fasting due to a proposed beneficial effect on the gut barrier function. The aim

Complex formation in solutions of oppositely charged polyelectrolytes at different polyion compositions and salt content

The formation of complexes in solutions containing positively charged polyions (polycations) and a variable amount of negatively charged polyions (polyanions) has been investigated by Monte Carlo simulations. The polyions were described as flexible chains of charged hard spheres interacting through a screened Coulomb potential. The systems were analyzed in terms of cluster compositions, structure

Pubertal bone growth in the femoral neck is predominantly characterized by increased bone size and not by increased bone density-a 4-year longitudinal study.

Fragility fractures are correlated to reduced bone size and/or reduced volumetric bone density (vBMD). These region-specific deficits may originate from reduced mineral accrual and/or reduced skeletal growth during the first 2 decades of life. Before pathological development can be defined, normal skeletal growth must be described. To evaluate growth of bone size, accrual of bone mineral content (

Getting a grip on proteomics data - Proteomics Data Collection (ProDaC)

In proteomics, rapid developments in instrumentation led to the acquisition of increasingly large data sets. Correspondingly, ProDaC was founded in 2006 as a Coordination Action project within the 6th European Union Framework Programme to support data sharing and community-wide data collection. The objectives of ProDaC were the development of documentation and storage standards, setup of a standar