Background: Tamoxifen is used in endocrine treatment of breast cancer to inhibit estrogen signaling. A set of strati‐ ed ER‐positive and ER‐negative tumor sections was subjected to manual deposition of tamoxifen solution in order to investigate its spatial distribution upon exposure to interaction within thin tissue sections. Methods: The localization of tamoxifen in tumor sections was assessed by

Specialnummer om film och historia: Ledare (Michael Tapper), Clio på Bio: Filmer, fotnoter och Hollywood (Ulf Zander), Visuell historiografi: Hayden White, narrativism och film (Mats Jönsson), Historia, fiktion, mytologi: Oliver Stone och debatten om JFK (Michael Tapper), Historia på film: Två intervjuer med Oliver Stone (Mark C Carnes, Gary Crowdus), Neorealism = mc2: Roberto Rossellini och teori

Innehåll: Ledare (Michael Tapper), Amerikanska mardrömmar: Robin Wood och 1970-talets amerikanska skräckfilmsvåg (Olof Hedling), Självspeglande fasor: Skräckfilmen 1980-2001 (Michael Tapper), Monster med rötter i arbetarklassen: Intervju med George Romero (Richard Porton), Apocalypse Now?: George Romero och de levande döda (Robin Wood), Från monstermamma till "tredje könet": Kvinnlig abjektion i D

Introduction: Regional and hospital decision-makers increasingly require analyses assessing the cost-benefit profile of new cancer drugs. This analysis evaluates the cost-benefit profile of nano albumin-bound paclitaxel (nab-paclitaxel) in pancreatic cancer, versus other drugs indicated in high-unmet need solid tumour indications in Nordic countries (Sweden, Denmark, Finland, Norway and Sweden). M

Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD) is based on the ratio of forced expiratory volume in 1 second (FEV1)/vital capacity (VC), either as a fixed value 1/VC ratio in a general population setting. The second aim was to evaluate the characteristics of subjects with COPD who obtained a higher SVC than FVC. Methods: Subjects (n=1,050) aged 50-64 years were i

Peak bone mass is normally reached in the third decade of life. Previously, in the population-based PEAK-25 cohort (n = 1061, age 25.5 ± 0.2), we demonstrated that bone mineral density in the population-based PEAK-25 cohort is comparatively high; therefore, this study aimed to determine if the calcaneus microarchitecture mirrored this. In the process, we describe normative quantitative ultrasound

Are foreign ministers punished for their performance in office, or when the country loses a war? The literature has increasingly recognized the importance of individual leaders when explaining foreign policy outcomes. Several scholars have focused on the survival of leaders as an important predictor of war onset, which has created an interest in predicting the survival of heads of governments. We

Why are some states more corrupt than others? Previous research explaining corruption suggests that multiparty governments are associated with higher levels of corruption since it is difficult for voters to hold parties in such cabinets accountable. Drawing on the literature on coalition governance, we suggest that a lack of government corruption has more to do with the ability of other key politi

The relationship between international migration and the welfare state is a hotly contested topic: some scholars argue that migration will, in the long run, erode support for the welfare state; others argue that the welfare state has inherent qualities that insulate it from such erosion. We place this debate in historical perspective by exploring the period when the latent tension between cross-bo

The idea that two objects can coincide—by sharing all their proper parts, or matter—yet be non-identical, results in the “Problem of Coincident Objects”: in what relation do objects stand if they are not identical but share all their proper parts? One solution is to introduce material constitution. In this paper, I argue that this is ad hoc since, first, this solution cannot be generalized to solv

This article discusses the current self-confidence and apparent success—at least by market/popularity measures—of leadership studies (LS) in general and transformational leadership (TFL) in particular. An alternative interpretation is offered, suggesting that it is the ideological character of these approaches that account for their “success,” at least in quantitative terms. Their wide appeal need

This work presents a digital calibration technique in continuous-time (CT) ΔΣ analog to digital (A/D) converters. The converter is clocked at 144MHz with a low oversampling ratio (OSR) of only 8. Dynamic element matching (DEM) is not efficient to linearize the digital to analog converter (DAC) when the OSR is very low. Therefore, non-idealities in the outermost multi-bit feedback DAC are measured

A themed journal issue which contains six commissioned essays + an editorial about the phenomenon of sex in the cinema, television and on the internet since the historical breakthrough of sex research by Alfred C. Kinsey in the late 1940s. The essays span a wide array of topics including, to name a few, the developments within obscenity law in the US, sex in the work of European art cinema auteurs

Special journal issue in film and history.

This paper reports the interim results of an ongoing systematic review of the available evidence for the effectiveness of nursing care for people with Parkinson's disease (PD). Five clinical and four health-economic evaluations suggest that the clinical and cost effectiveness of nursing care for PD remain inconclusive. This is in contrast to clinical experience and may be due to issues related to