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Hemolytic uremic syndrome, a life-threatening disease often accompanied by acute renal failure, usually occurs after gastrointestinal infection with Shiga toxin 2 (Stx2)-producing Escherichia coli. Stx2 binds to the glycosphingolipid globotriaosylceramide receptor, expressed by renal epithelial cells, and triggers apoptosis by activating the apoptotic factor Bax. Signaling via the ouabain/Na,K-ATP

This article deals with the Finnish-Swedish, Jewish composer and author Moses Pergament and his relationship with Wagner's theories, anti-Semitism in particular, and their influence on the development of modern Swedish classical music during the interwar period. The author emphasizes the importance of recognizing that Pergament's reaction to Wagner's cultural theories was part and parcel of his st

The aim of this article is to offer an object lesson in how historians could make use of feature film as primary source material if they were to use the analytical tools developed in the field of film studies and by historians who started to work with film in the 1970s and 1980s. My own work on representations of maidservants in Swedish feature films in the 1930s and 1940s is used as a case in poi

Before wood ash can be used as a soil fertilizer, concentrations of environmentally hazardous compounds must be investigated. In this study, total and leachable concentrations of 16 polycyclic aromatic hydrocarbons (PAHs) were determined in four ash samples and one green liquor sludge. The ash sample with the highest carbon content also contained high levels of PAHs; three of the ash samples had t

Based on an interview with a hip-hop artist from Eastern Poland, this article critically assesses amateur art pro-duction proliferating throughout the globe today through individuals’ creative usages of new ICTs and new media affordances. The post-Fordist material and ideological context of contemporary social life is the main focus point of the article’s critique. Scarcity, dispossession, and ent

The castes of social insects provide outstanding opportunities to address the causes and consequences of evolution of discrete phenotypes, i.e., polymorphisms. Here we focus on recently described patterns of a positive association between the degree of caste-specific gene expression and the rate of sequence evolution. We outline how neutral and adaptive evolution can cause genes that are morph-bia

The authors present a very interesting data set on the acceleration effects on sheet flow transport and compare their experimental results with different transport practical formulas. However, they omit some previous work by Camenen and Larson (2007) that we would like to bring to the authors' attention. A more extensive discussion on some aspects of the acceleration effects is also lacking in the

Popular Abstract in English This doctoral thesis investigates the onset of cardiovascular disease with a focus on socioeconomic differences as explanatory factors. Analyzing a contemporary population of natives and foreign-born individuals in Sweden, socioeconomic status is operationalized through a variety of measures. The importance of this study is found in the high cost of cardiovascular interThis doctoral thesis investigates the relationship between socioeconomic status and the onset of cardiovascular disease in a contemporary population of natives and foreign-born individuals in Sweden. The complexity of individual socioeconomic characteristics and the interrelationship with other cardiovascular risk factors is the focus of the studies in this thesis. As in most developed countries,

Sepsis is one of leading cause of death despite aggressive surgical intervention and antibiotic therapies. Excessive neutrophil recruitment is a major feature in early phase with immune system dysfunction at later phase. Lung is the most vulnerable, critical and sensitive organ during sepsis process. The aim of thesis was to prevent excessive neutrophil accumulation in lung parenchyma on one hand,

A neutron transport system for the planned imaging instrument ODIN at the future European Spallation Source (ESS) based on neutron optical components was designed and optimized. Different ways of prompt pulse suppression were studied. The spectral performance of the optimal neutron guide configuration is presented. In addition, the influence of the gaps in the guide system needed for the required

The aim of this study was to ascertain whether there is a relationship between plant species richness and plant-available N, P and water in an environment subject to little anthropogenic disturbance. To accomplish this we studied the vegetation in matorral shrub-lands in northern Patagonia, Argentina. Due to the variation in slope, precipitation and aspect between the sites water status was determ

Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplasia that presents early in infancy. The main hematopoietic symptoms include macrocytic anemia with reticulocytopenia and selective absence of erythroid precursors in a normocellular bone marrow. In addition to the hematopoietic symptoms, DBA is characterized by the presence of physical abnormalities and cancer predisposition. Mutations

Monitoring and evaluation of malaria control in pregnancy is essential for assessing the efficacy and effectiveness of health interventions aimed at reducing the major burden of this disease on women living in endemic areas. Yet there is no currently integrated strategic approach on how this should be achieved. Malaria control in pregnancy is formulated in relation to epidemiological patterns of e

A method of separately quantifying organic and inorganic 14C compounds present in spent ion-exchange resins and process water from nuclear power reactors has been developed. Extraction of carbon compounds is accomplished by means of acid stripping (inorganic 14C) and subsequent wet oxidation (organic 14C) or by N2 purging in combination with a catalytic furnace (oxidized and reduced gaseous compou

Antalet cirkulationsplatser fortsätter att öka. Personer med synskada uppger att det är svårt för dem att korsa gatan vid cirkulationsplatser och det finns idag inte tillräckligt med kunskap för att lösa tillgänglighetsproblemen. Den forskning som finns idag studerar enbart blinda personer, trots att den stora majoriteten synskadade har synrester. Syftet med denna studie var att fastställa hur cirAntalet cirkulationsplatser fortsätter att öka. Personer med synskada uppger att det är svårt för dem att korsa gatan vid cirkulationsplatser och det finns idag inte tillräckligt med kunskap för att lösa tillgänglighetsproblemen. Den forskning som finns idag studerar enbart blinda personer, trots att den stora majoriteten synskadade har synrester. Syftet med denna studie var att fastställa hur cir

A phase-field based topology optimization approach is considered for the maximum stiffness or minimum compliance problem. The objective functional to be minimized consists in addition to the compliance a cost for gray solutions and a cost for interfaces between void and full material. Since the interfaces between void and full material are penalized via a volume integral in the original phase-fiel

The exchange of persistent organic pollutants (POPS) between different compartments of a typical mature boreal forest was investigated. The study focused on fluxes of polychlorinated biphenyls (PCBs) between the atmosphere, vegetation and soil, and within the soil to assess whether this type of forest acts as a final sink-or temporary repository for POPs. The study, at a Swedish site, suggested to

Screening mammography plays a key role in the early detection of breast cancer, however, estimates of sensitivities (48-88%) and specificities (82-98%) suggest that the diagnostic accuracy can be improved (1, 2, 3). Breast tomosynthesis (BT) is a 3D technique that is expected to improve breast cancer detection compared to screen-film and digital mammography DM). This work presents two clinical obs