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Supervisory observer for parameter and state estimation of nonlinear systems using the DIRECT algorithm

A supervisory observer is a multiple-model architecture, which estimates the parameters and the states of nonlinear systems. It consists of a bank of state observers, where each observer is designed for some nominal parameter values sampled in a known parameter set. A selection criterion is used to select a single observer at each time instant, which provides its state estimate and parameter value

Optical characterization of Chinese hybrid rice using laser-induced fluorescence techniques—laboratory and remote-sensing measurements

Chinese hybrid rice of different varieties, growing in paddies in the Pingqiao district, north of Xinyang city, Henan province, China, was studied in detailed spectroscopic characteristics using laser-induced fluorescence. The base for the studies was the new South China Normal University mobile lidar laboratory, which was dispatched on site, providing facilities both for laboratory studies using

Power-aware cloud brownout : Response time and power consumption control

Cloud computing infrastructures are powering most of the web hosting services that we use at all times. A recent failure in the Amazon cloud infrastructure made many of the website that we use on a hourly basis unavailable1. This illustrates the importance of cloud applications being able to absorb peaks in workload, and at the same time to tune their power requirements to the power and energy cap

DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune condition with heterogeneous presentation and complex aetiology where DNA methylation changes are emerging as a contributing factor. In order to discover novel epigenetic associations and investigate their relationship to genetic risk for SLE, we analysed DNA methylation profiles in a large collection of patients with SLE and he

L1 and H-infinity optimal control of positive bilinear systems

In this paper we consider L1 optimal and H-infinity optimal control problems for a particular class of Positive Bilinear Systems that arise in drug dosage design for HIV treatment. Starting from existent characterizations of the L1-norm for positive systems, a convex formulation for the first problem is provided. As for the H-infinity case, we propose an algorithm based on the iterative solution o

Why Do Sex Chromosomes Stop Recombining?

It is commonly assumed that sex chromosomes evolve recombination suppression because selection favours linkage between sex-determining and sexually antagonistic genes. However, although the role of sexual antagonism during sex chromosome evolution has attained strong support from theory, experimental and observational evidence is rare or equivocal. Here, we highlight alternative, often neglected,

Induction of S100A9 homodimer formation in vivo

We show here that increased S100A8 and S100A9 protein expression is induced in spleen of animals with active inflammation or with inoculated tumors. In tumor bearing animals an increased expression was also detected in the lung. To further analyze the induced proteins, we performed chemical cross-linking followed by Western blotting. We observed in protein extracts from spleen that both S100A8/S10

Identification of manifest diabetes and complication development in gestational diabetes mellitus. The pursuit for biomarkers.

Gestational diabetes mellitus (GDM) is a type of diabetes which is first recognised during pregnancy. In the county of Skåne in Southern Sweden, over 2% of all pregnancies are complicated by GDM, a number that is generally several times higher worldwide. Women with GDM during pregnancy are at risk of developing GDM anew in subsequent pregnancies, but also have an increased risk of developing postp

Contrasting results from GWAS and QTL mapping on wing length in great reed warblers

A major goal in evolutionary biology is to understand the genetic basis of adaptive traits. In migratory birds, wing morphology is such a trait. Our previous work on the great reed warbler (Acrocephalus arundinaceus) shows that wing length is highly heritable and under sexually antagonistic selection. Moreover, a quantitative trait locus (QTL) mapping analysis detected a pronounced QTL for wing le

Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation

Autoimmune diseases, such as psoriasis and arthritis, show a patchy distribution of inflammation despite systemic dysregulation of adaptive immunity. Thus, additional tissue-derived signals, such as danger-associated molecular patterns (DAMPs), are indispensable for manifestation of local inflammation. S100A8/S100A9 complexes are the most abundant DAMPs in many autoimmune diseases. However, regula

Perioperative Hyperlactemia Is a Poor Predictor of Outcome in Patients Undergoing Surgery for Acute Type-A Aortic Dissection

Objective: In patients presenting with acute type-A aortic dissection (aTAAD), lactic acid measurement is a frequently used analysis for diagnosis of acute ischemia, which may have a dismal prognosis. The aim of the current study was to determine the performance of perioperative arterial lactic acid measurements in predicting outcome in aTAAD patients. Design: Retrospective, observational study. S

UbiCompass : An IoT interaction concept

Lately, different wearable form factors have reached the consumer domain. Wearables enable at-a-glance access to information and can continually sense the surrounding environment. Internet of Things (IoT) researchers have focused on the main enabling factors: The integration of several technologies and communication solutions. Less effort has been devoted to exploring how not-so-tech-savvy end use

Blood Lead Levels and Decreased Kidney Function in a Population-Based Cohort

Background: Environmental lead exposure has been associated with decreased kidney function, but evidence from large prospective cohort studies examining low exposure levels is scarce. We assessed the association of low levels of lead exposure with kidney function and kidney disease. Study Design: Prospective population-based cohort. Setting & Participants: 4,341 individuals aged 46 to 67 years

Lessons in Lateralisation from the Insects

The behavioural lateralisation of a species is thought to be influenced by social organisation. However, recent studies of insect species with different social structures suggest that traits showing both population-level and individual-level lateralisation can be found in single species. This has broad implications for our understanding of how lateralisation and handedness evolves.

Urban Living Labs and the Role of Users in Co-creation

Urban living labs (ULLs) offer opportunities to foster sustainability in cities. They are sites to design, test and learn from innovation in real time. A key element in the operation and success of ULLs is user involvement. Users are often viewed as co-creators who shape ULL outcomes by contributing with their knowledge and experi ence. The transformative potential of ULLs for sustainability is of

Estimation of the conversion coefficients from dose-area product to effective dose for barium meal examinations for adult patients

Fluoroscopic examinations of the upper gastro-intestinal tract and, especially, barium meal examinations, are commonly performed in a majority of hospitals. These examinations are associated both with substantial individual patient doses and contribution to the collective dose from medical exposure. Effective dose estimation for this type of examinations is complicated due to: 1) the necessity to

Self-descriptions on LinkedIn : Recruitment or friendship identity?

We used quantitative semantics to find clusters of words in LinkedIn users' self-descriptions to an employer or a friend. Some of these clusters discriminated between worker and friend conditions (e.g., flexible vs. caring) and between LinkedIn users with high and low education (e.g., analytical vs. messy).

Spatially Coupled Turbo-Like Codes

The focus of this thesis is on proposing and analyzing a powerful class of codes on graphs---with trellis constraints---that can simultaneously approach capacity and achieve very low error floor. In particular, we propose the concept of spatial coupling for turbo-like code (SC-TC) ensembles and investigate the impact of coupling on the performance of these codes. The main elements of this study ca