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Three major Lyme Borrelia genospecies (Borrelia burgdorferi sensu stricto, B. afzelii and B. garinii) identified by PCR in cerebrospinal fluid from patients with neuroborreliosis in Sweden.

The Lyme Borrelia genospecies Borrelia afzelii and B. garinii have previously been isolated using a culture method in Swedish patients with Lyme borreliosis (LB). There are reports suggesting that the genospecies distribution in human tissue specimens as determined by molecular methods is different from that obtained by culture. In the present study, we developed a nested PCR for detection of Lyme

Estimates of regional surface carbon dioxide exchange and carbon and oxygen isotope discrimination during photosynthesis from concentration profiles in the atmospheric boundary layer

The integrating properties of the atmospheric boundary layer allow the influence of surface exchange processes on the atmosphere to be quantified and estimates of large-scale fluxes of trace gases and plant isotopic discrimination to be made. Five flights were undertaken over two days in and above the convective boundary layer (CBL) in a vegetated region in central Siberia. Vertical profiles of CO

Regulation of angiogenesis by tissue factor cytoplasmic domain signaling

Hemostasis initiates angiogenesis-dependent wound healing, and thrombosis is frequently associated with advanced cancer. Although activation of coagulation generates potent regulators of angiogenesis, little is known about how this pathway supports angiogenesis in vivo. Here we show that the tissue factor (TF)-VIIa protease complex, independent of triggering coagulation, can promote tumor and deve

Numerical Modelling of Soot Formation in Turbulent Non-Premixed Flames

This thesis describes an extended flamelet approach for modelling of soot formation in turbulent hydrocarbons diffusion flames. Detailed chemical kinetic mechanisms are used to compute species concentrations, temperature, density and soot formation rates as functions of flamelet coordinates in the space of mixture fraction and scalar dissipation rate. An ensemble average based on a presumed probab

Pseudospectra of semiclassical (pseudo-) differential operators

The pseudo-spectra (or spectral instability) of non-selfadjoint operators is a topic of current interest in applied mathematics. For example, in computational fluid dynamics it affects the study of the stability of laminar flows. In fact, even for the most basic flows, the computations entirely fails to predict what is observed in the experiments. The explanation is that for non-normal operators

Youth - the future manpower. Studies on unemployment, quality of life and work attitudes.

Popular Abstract in Swedish Arbetslivet är en av de viktigaste delarna i människors livssituation och ett av de viktigaste incitamenten för välfärden i ett samhälle. Stora förändringar har skett för ungdomar beträffande arbetslivet och inträdet i arbetslivet under de senaste decennierna. Bl.a. de stora förändringarna gör att ny kunskap krävs för att ge möjlighet att stärka ungdomarna i deras inträThe aim was to gain knowledge of experiences of unemployment in young adults with special regard to quality of life (QOL) and to highlight work attitudes and related factors among adolescents. Three studies were performed in Kristianstad municipality, Sweden. In Study 1, a questionnaire was sent in 1998 to 264 unemployed young adults (md=22 years, range 20?25) and to a control group of 528 random

Alport syndrome caused by inversion of a 21 Mb fragment of the long arm of the X-chromosome comprising exon 9 through 51 of the COL4A5 gene

The X-linked form of Alport syndrome (AS) is caused by mutation in the COL4A5 gene located at Xq22.3 and encoding the alpha 5-chain of type IV-collagen. More than 400 different mutations have so far been detected in the COL4A5 gene. Not all mutations, however, will be detected using an exon-by-exon mutation detection strategy such as SSCP analysis or direct sequencing. We have previously reported

Waist measurement correlates to a potentially atherogenic lipoprotein profile in obese 12-14-year-old children

Epidemiological studies have indicated a relationship between overweight and cardiovascular disease. The present investigation was undertaken to identify anthropometric variables in childhood which may reflect the risk of cardiovascular disease in terms of unfavourable changes in apolipoprotein and lipid concentrations. Twenty-nine obese 14-year-olds and 32 obese 12-year-olds were recruited from a

Electrochemically induced oxidative damage to double-stranded calf thymus DNA adsorbed on gold electrodes

Electrochemically induced oxidative damage to DNA was studied with double-stranded calf thymus DNA immobilized directly on a gold electrode surface. Pre-polarization of the DNA-modified electrodes at +0.5 V versus Ag/AgCl reference electrode, in a free from DNA blank buffer solution, pH 7.4, allowed for subsequent detection of direct electrochemical oxidation of adsorbed on gold DNA, in the potent

Resolution of 2D Wenner resistivity imaging as assessed by numerical modelling

Modelling of 2D resistivity imaging was done in order to understand the principle resolution of the technique in different geological situations, and for assessing the behaviour of the interpretation methods under controlled circumstances. The Wenner array was used throughout. The results show that the 1D approximation only provides reasonable results in environments with very gradual lateral resi

Streptococcal M protein and human C4BP

Antigenic variation of surface proteins allows microorganisms to evade the immune system of the infected host. This phenomenon represents an apparent paradox, because the variable protein must retain an important function, while its antigenic properties vary extensively. The surface associated M protein of Streptococcus pyogenes, a common human pathogen, exhibits antigenic variation due to an N-te

Effect of acupressure on nausea and vomiting during pregnancy. A randomized, placebo-controlled, pilot study

OBJECTIVE: To compare the antiemetic effect of acupressure at the Neiguan point (P6) in a group of healthy women with normal pregnancy and nausea and vomiting during pregnancy (NVP) with a similar group receiving acupressure at a placebo point and another, similar group not receiving any treatment. STUDY DESIGN: A randomized, placebo-controlled, pilot study involving 60 women. RESULTS: It is possi

Long-term regulation of cyclic nucleotide phosphodiesterase type 3B and 4 in 3T3-L1 adipocytes.

Phosphodiesterase 3B (PDE3B), is known to play an important role in acute insulin and cAMP-mediated regulation of lipid metabolism, and PDE4 are the main PDE types expressed in adipocytes. Here, we show that members of all PDE4 isoforms are expressed in 3T3-L1 and primary mouse adipocytes. Long-term treatment of 3T3-L1 adipocytes with insulin induced up-regulation of PDE3B and PDE4D in a phosphati