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Reaction Mechanism of Manganese Superoxide Dismutase Studied by Combined Quantum and Molecular Mechanical Calculations and Multiconfigurational Methods.

Manganese superoxide dismutases (MnSODs) are enzymes that convert two molecules of the poisonous superoxide radical into molecular oxygen and hydrogen peroxide. During the reaction, the manganese ion cycles between the Mn(2+) and Mn(3+) oxidation states and accomplishes its enzymatic action in two half-cycles (corresponding to the oxidation and reduction of O(2)(*-)). Despite many experimental and

Simultaneous determination of fragmentation and coalescence rates during pilot-scale high-pressure homogenization

The emulsification process is primarily determined by the rate of fragmentation and coalescence of emulsion drops. However, there is presently no fast, reliable method for measuring these rates for pilot and production scale high pressure homogenizers. In this paper a method for simultaneous estimating fragmentation and coalescence is developed and tested based on the work of Hounslow and Ni (2004

Barnskötarna, förskollärarna och det förtydligade pedagogiska uppdraget

Syftet med rapporten var att med utgångspunkt i den reviderade versionen av förskolans läroplan, Lpfö 98, belysa hur man som yrkesverksam i förskolan upplever den numera framskrivna och allt tydligare åtskillnad i uppdrag mellan förskolans olika yrkeskategorier, främst förskollärare och barnskötare. Vidare belyser rapporten förskolepersonals tankar och åsikter kring förskolechefens uppdrag: - Hur

The role of body size in ecological diversification and reproductive isolation in a sister species pair of triplefin fishes

The effect of body size on spatial resource competition and reproductive isolation was examined in a sister species pair of subtidal triplefin fishes (F. Tripterygiidae) in New Zealand. Ruanoho decemdigitatus and Ruanoho whero have overlapping sympatric distributions and differ in body size, attaining a total length of 12 cm and 9 cm, respectively. R. decemdigitatus was most commonly found in shel

Knowledge as Action : An Anthropological Study of Attac Sweden

The purpose of this thesis is to examine knowledge production around globalisation and politics in Attac Sweden. As a part of the global justice movement that emerged in the 1990s, the organisation Attac Sweden related to a larger process. Attac Sweden was also central in debates about globalisation in the Swedish political context around the years 2000 and 2001. This study is based both on ethnog

Kategoriseringar av barn i förskoleåldern : Styrning & administrativa processer

The present thesis investigates, analyses and critically discusses the manner in which children with special needs are categorised in the Swedish preschool. The emergence of the category and its construction depends on a number of “truths” concerning children, related to historical and cultural processes in society. A main focus of the thesis is to investigate how legitimacy is established for the

Taking the environment online : issue and link networks surrounding personal green living blogs

Purpose: This article explores the construction and configuration of environmentally friendly living through making visible the link networks that surround personal greener living blogs.The following questions guide the exploration: Which types of organisations/actors structure the issue network of green living blogs as it emerges through links? How do these links contribute to carving out themati

Breast Cancer Screening With Tomosynthesis-Initial Experiences

Experiences gained so far using tomosynthesis for breast cancer screening will be reported. A short summary of results from preparatory studies will also be presented. The sensitivity and specificity of breast tomosynthesis (BT) will be compared with conventional two-dimensional digital mammography (DM) for breast cancer screening in a population-based study. Over 2000 women have been examined so

TBscore: Signs and symptoms from tuberculosis patients in a low-resource setting have predictive value and may be used to assess clinical course

We developed a clinical score to monitor tuberculosis patients in treatment and to assess clinical outcome. We used the WHO clinical manual to choose signs and symptoms, including cough, haemoptysis, dyspnoea, chest pain, night sweating, anaemia, tachycardia, lung-auscultation finding, fever, low body-mass index, low mid-upper arm circumference giving patients a TBscore from 0 to 13. We validated

Mobility and satisfaction with lower-limb prostheses and orthoses among users in Sierra Leone: A cross-sectional study

Objectives: To investigate patients' mobility and satisfaction with their lower-limb prosthetic or orthotic device and related service delivery in Sierra Leone; to compare groups of patients regarding type and level of assistive device, gender, area of residence, income; and to identify factors associated with satisfaction with the assistive device and service. Methods: A total of 139 patients ans

Cooperation with public research institutions and success in innovation: Evidence from France and Germany

We evaluate the impact of cooperation with public research on firms' product and process innovations in France and Germany using Community Innovation Survey data from 2004 and 2008. We find that cooperating with public research increases product innovation, but has no effect on process innovation, which depends more on firms' openness. Our benchmark estimates, which are very similar in 2004 and 20

Distributional properties of the negative binomial Lévy process

The geometric distribution leads to a Lévy process parameterized by the probability of success. The resulting negative binomial process (NBP) is a purely jump and non-decreasing process with general negative binomial marginal distributions. We review various stochastic mechanisms leading to this process, and study its distributional structure. These results enable us to establish strong convergenc

Critical threshold size for overwintering sandeels (Ammodytes marinus)

Several ecologically and commercially important fish species spend the winter in a state of minimum feeding activity and at lower risk of predation. To enable this overwintering behaviour, energetic reserves are generated prior to winter to support winter metabolism. Maintenance metabolism in fish scales with body size and increases with temperature, and the two factors together determine a critic

Revisiting reflexive archaeology at Çatalhöyük : integrating digital and 3D technologies at the trowel’s edge

The aim of this paper is to summarize progress in the development of reflexive methods at Çatalhöyük over the past 20 years, and to describe some recent innovations that have used digital and 3D technologies to enhance the original reflexive aims. While digital technologies were not at the forefront of the methods described in an initial account of reflexive methods published in Antiquity (Hodder

Entity extraction: From unstructured text to DBpedia RDF triples

In this paper, we describe an end-to-end system that automatically extracts RDF triples describing entity relations and properties from unstructured text. This system is based on a pipeline of text processing modules that includes a semantic parser and a coreference solver. By using coreference chains, we group entity actions and properties described in different sentences and convert them into en

Intestinal dendritic cell migration and induction of T cell responses

The intestine represents the body’s largest surface exposed to the outer world and is thus a major entry site for pathogens such as bacteria and viruses. The intestinal immune system has the important task of protecting us against infection while maintaining tolerance against the vast amount of commensal microbes populating the intestinal tract and the multitude of foreign antigen present in the d

Low serum levels of short-chain fatty acids after lactulose ingestion may indicate impaired colonic fermentation in patients with irritable bowel syndrome.

Ingestion of low-digestible carbohydrates triggers symptoms in patients with irritable bowel syndrome (IBS). These carbohydrates become substrates for microbial fermentation in the colon, yielding short-chain fatty acids (SCFAs) that are readily absorbed. Aiming to compare colonic fermentation in patients with IBS and healthy controls, we analyzed the concentrations of SCFA in serum at fasting and

Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF.

Caveolae are invaginations in the plasma membrane that depend on caveolins and cavins for maturation. Here, we investigated the pulmonary phenotype in mice lacking cavin-1. Bright field and electron-microscopy showed that the cavin-1-deficient mice lacked caveolae in the lung, had an increased lung tissue density, and exhibited hypertrophic remodeling of pulmonary arteries. The right ventricle of