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Actin-like protein associated with plasma membranes from Euglena gracilis

Microtubules are characteristic components of the membrane skeleton of Euglena gracilis, but whether microfilaments are present has been controversial. We here present evidence that an actin-like protein may indeed be associated with the plasma membrane (PM) of E. gracilis. Firstly, a 47 kDa, PM-associated, polypeptide was recognized by an anti-amoeba actin antibody. Secondly, this 47 kDa protein

Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort

Fish is a source of important nutrients and may play a role in preventing heart diseases and other health outcomes. However, studies of overall mortality and cause-specific mortality related to fish consumption are inconclusive. We examined the rate of overall mortality, as well as mortality from ischaemic heart disease and cancer in relation to the intake of total fish, lean fish, and fatty fish

Cost-effectiveness of conservation payment schemes for species with different range sizes

Payments to compensate landowners for carrying out costly land-use measures that benefit endangered biodiversity have become an important policy instrument. When designing such payments, it is important to take into account that spatially connected habitats are more valuable for many species than isolated ones. One way to incentivize provision of connected habitats is to offer landowners an agglom

Impacts of experimentally imposed drought on leaf respiration and morphology in an Amazon rain forest

P>1. The Amazon region may experience increasing moisture limitation over this century. Leaf dark respiration (R) is a key component of the Amazon rain forest carbon (C) cycle, but relatively little is known about its sensitivity to drought. 2. Here, we present measurements of R standardized to 25 degrees C and leaf morphology from different canopy heights over 5 years at a rain forest subject to

Benefits and Adverse Events in Younger Versus Older Patients Receiving Neoadjuvant Chemotherapy for Osteosarcoma: Findings From a Meta-Analysis.

PURPOSEThe LIVESTRONG Young Adult Alliance has conducted a meta-analysis of individual patient data from prospective neoadjuvant chemotherapy osteosarcoma studies and registries to examine the relationships of sex, age, and toxicity on survival. PATIENTS AND METHODSSuitable data sets were identified by a survey of published data reported in PubMed. The final pooled data set comprised 4,838 patient

Cerebrospinal fluid analysis detects cerebral amyloid-β accumulation earlier than positron emission tomography.

Cerebral accumulation of amyloid-β is thought to be the starting mechanism in Alzheimer's disease. Amyloid-β can be detected by analysis of cerebrospinal fluid amyloid-β42 or amyloid positron emission tomography, but it is unknown if any of the methods can identify an abnormal amyloid accumulation prior to the other. Our aim was to determine whether cerebrospinal fluid amyloid-β42 change before am

Allergic Airway Inflammation Initiates Long-Term Vascular Remodeling of the Pulmonary Circulation.

Background: Asthma and allergic airway inflammation are associated with persistent structural alterations in the bronchi, i.e. airway remodeling. Previous studies have shown that during allergic airway inflammation, similar structural alterations may also be evoked in the pulmonary circulation. However, it remained unknown whether remodeling of the pulmonary circulation is as persistent as airway

Low Atrial Fibrillatory Rate Is Associated with Poor Outcome in Patients with Mild to Moderate Heart Failure.

BACKGROUND: -Atrial fibrillatory rate (AFR) is a measure of atrial remodeling caused by atrial fibrillation (AF) and its acceleration negatively affects outcome of interventions for persistent AF. However, the prognostic value of AFR in patients with CHF has not been studied. We sought to evaluate whether AFR can predict outcome in patients with mild to moderate (NYHA II-III) congestive heart fail

IGF-1 protects against diabetic features in an in vivo model of Huntington's disease.

Huntington's disease (HD) is the most prevalent polyglutamine expansion disorder. HD is caused by an expansion of CAG triplet in the huntingtin (HTT) gene, associated with striatal and cortical neuronal loss. Central and peripheral metabolic abnormalities and altered insulin-like growth factor-1 (IGF-1) levels have been described in HD. Thus, we hypothesized that restoration of IGF-1-mediated sign

Decline in human T-cell lymphotropic virus-1 prevalence in urban areas of Bissau, Guinea-Bissau: exploring the association with HIV infections.

In 2006, a cross-sectional survey of 384 randomly selected houses within a community-based follow-up study was conducted to assess the human T-cell lymphotropic virus (HTLV) prevalence in Bissau. Changes in prevalence and incidence rates were assessed based on a similar survey carried out 10 years earlier. The prevalence of HTLV-1 declined significantly from 3.5% in 1996 to 2.3% in 2006. The incid

Determination of Radiative Lifetimes of Neutral Bismuth By Time-resolved Uv-vuv Laser Spectroscopy

Time-resolved laser spectroscopy was used to measure natural radiative lifetimes of ten excited states of neutral bismuth. Four levels of the 6p(2)ns (4)p(1/2) sequence (n = 7,8,9,10) and the 6p(2)7s P-4(3/2),(5/2) and 6p(2)nd(2)D(2/3;5/2) (n = 6,7) levels were investigated. The results are compared with previous data when possible. Revised absolute transition probabilities for 26 lines are given.

Dynamical modelling of haematopoiesis: an integrated view over the system in homeostasis and under perturbation.

A very high number of different types of blood cells must be generated daily through a process called haematopoiesis in order to meet the physiological requirements of the organism. All blood cells originate from a population of relatively few haematopoietic stem cells residing in the bone marrow, which give rise to specific progenitors through different lineages. Steady-state dynamics are governe

The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke.

Stroke leads to brain damage with subsequent slow and incomplete recovery of lost brain functions. Enriched housing of stroke-injured rats provides multi-modal sensorimotor stimulation, which improves recovery, although the specific mechanisms involved have not been identified. In rats housed in an enriched environment for two weeks after permanent middle cerebral artery occlusion, we found increa

The Necessity of Repackaging and Relabelling Trade Marked Goods

Trade marks perform a variety of economic functions in a commercial environment and plays an important role in a market economy. Therefore, there is a need to protect the distinguishing of competing goods and services offered by undertakings and accordingly to avoid consumer confusion. The origin function of the trade mark guarantees that all products bearing a trade mark emanate from the same com

Skälig häktningstid - Rättsdogmatisk undersökning och fallstudie

Föreliggande uppsats studerar frågan hur länge en person lagligen kan hållas häktad utan åtal väcks och rättegång hålls. Uppsatsen är uppdelad i två delar. Den första delen är en deskriptiv studie som beskriver tillämpliga häktningsbestämmelser i RB och diskuterar frågan om det är möjligt att tala om skälig häktningstid enligt svensk rätt. Enligt svensk lagstiftning finns det nämligen ingen bestäm

EU-lagstiftning om avfallstransporter under förändring - Konsekvenser av förordning 1013/2006

Alla resurser på marknaden är dömda att förr eller senare bli till avfall och all produktion skapar någon form av avfall. I nuläget deponeras 49 % av allt kommunalt avfall inom EU, 18 % förbränns och 33 % återvinns eller komposteras. Även om materialåtervinning och förbränning blir allt vanligare minskar inte den sammanlagda mängden deponerat avfall, eftersom vi också producerar mer avfall. Detta