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United and divided : Early modern economic history in Finnish and Swedish academic literature
In this chapter, we analyze Finnish and Swedish economic history research on these countries’ common past (prior to 1809) and the early modern era (defined here as between 1500 and 1850). Using extensive bibliometric databases, we show that even when they focus on the early modern era, economic historians most often analyze Finland and Sweden in terms of their modern borders. Researchers based in
Testing Phenotypic Models of Posttraumatic Stress Disorder and Alcohol Use Disorder Comorbidity Using Longitudinal Registry Data
Objective: Two predominant phenotypic models of causality exist to explain the high co-occurrence of posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD): the self-medication and susceptibility models. Population-based longitudinal studies that simultaneously examine both models are needed. Thus, the goal of the pres-ent study is to test these models using the Swedish National Regis
A nordic multicenter study on contemporary outcomes of pediatric short bowel syndrome in 208 patients
Background & aims: Despite advances in the management of short bowel syndrome related intestinal failure (SBS-IF), large-scale contemporary pediatric studies are scarce. The aim of this multicenter study was to assess key outcomes and clinical prognostic factors in a recent Nordic pediatric SBS-IF population. Methods: Patients with SBS-IF treated during 2010–2019, whose parenteral support (PS)
Municipally Owned Corporations in Sweden
The use of municipally owned corporations (MOCs) has a long tradition in Sweden. In this chapter we take the point of departure in this long tradition of MOCs when describing how the use of these corporations has developed over time as well as the conditions under which these MOCs operate has developed. In addition, some of the more problematic features of MOCs, that Swedish local governments stru
Viral bodies: racialised and gendered logics in the securitisation of migration during COVID-19 in Italy
Since the spread of the COVID-19 pandemic, migrants’ mobility has been increasingly securitised as governments have been adopting extraordinary measures to close both external and internal borders. Similarly, the presence of migrants within countries has often been met with lower levels of acceptance, leading to the implementation of discriminatory and xenophobic measures. Although debates on the
Manual-free software for a technical instrument
In workplaces, a lot of knowledge is lost when colleagues change positions. What was once obvious to one person can be incomprehensible to the next. This problem has been encountered by Probation Labs Sweden AB with their biochemical instrument, Labbot. Labbot facilitates researchers in automating their protein analysis. It works like a multi-tool where users can perform one or several tasks in a
Possibility to design and synthesize protein imprinted particles using surface-initiated atom transfer radical polymerization (SI-ATRP)
Two local minima for structures of [4Fe–4S] clusters obtained with density functional theory methods
[4Fe–4S] clusters are essential cofactors in many proteins involved in biological redox-active processes. Density functional theory (DFT) methods are widely used to study these clusters. Previous investigations have indicated that there exist two local minima for these clusters in proteins. We perform a detailed study of these minima in five proteins and two oxidation states, using combined quantu
Three concepts of globalization
This article is a brief inquiry into the meaning and function of the concept of globalization within the social sciences during the last decade. Describing the ontological presuppositions and historical trajectory of the concept of globalization, this article distinguishes three distinct senses of the idea - transference, transformation and transcendence - and argues that these senses have emerged
Entrepreneurship as emancipation: Adopting body work in the process of reducing constraints of marginalization
Exploring the Applications of Machine Learning in the Public Sector
Despite the many use cases for machine learning, it sees minimal usage in Sweden’s public sector today. It is important that the public sector in particular utilizes the most efficient tools available. For this reason, the Department of Employment and Social Services in Malmö has started a project to explore the viability of introducing machine learning to their work. This thesis corresponds to ro
Functional In Vivo Screening Identifies microRNAs Regulating Metastatic Dissemination of Prostate Cancer Cells to Bone Marrow
Distant metastasis is the major cause of cancer-related deaths in men with prostate cancer (PCa). An in vivo functional screen was used to identify microRNAs (miRNAs) regulating metastatic dissemination of PCa cells. PC3 cells transduced with pooled miRZiP™ lentivirus library (anti-miRNAs) were injected intraprostatic to 13 NSG mice followed by targeted barcode/anti-miR sequencing. PCa cells in th
The age-dependent association of Life's Simple 7 with transitions across cognitive states after age 60
Background: Life's Simple 7 (LS7) aims to promote ideal cardiovascular health (CVH). Its association with different cognitive states in the older old is unclear. Objectives: To assess the associations of LS7 with transitions across normal cognition, cognitive impairment, no dementia (CIND), and dementia and evaluate cognitive impairment-free years of life by LS7-defined CVH levels in older adults.
Particle Detection in Bone Marrow Using CNNs and Transformer Networks
The critical role of hematological stem cells, concentrated in bone marrow, in disease diagnosis makes the detection of these cells an imperative task. The current process, however, is slow and heavily reliant on expert interpretation, underscoring the need for automation. In this thesis, we collected a 20x microscopy dataset of real and fake bone marrow particles and fine-tuned several CNNs and T
A low-cost, long-running, open-source stereo camera for tracking aquatic species and their behaviours
Ecologists are now widely utilising video data to quantify the behaviours and interactions of animals in the wild. This process can be facilitated by collecting videos in stereo, which can provide information about animals' positions, movements and behaviours in three-dimensions (3D). However, there are no published designs that can collect underwater 3D stereo data at high spatial and temporal re
Urban Geopolitics and the Decentring of Migration Diplomacy in EU-Moroccan Affairs
In 2018, the International Organization for Migration stated that ‘migration has nearly become synonymous with urbanization, given the dominance of the city as the destination of most migrants’. The geopolitical dimension of migration governance is especially important in Mediterranean cities where the European Union’s (EU) efforts to push border management onto external actors has occurred alongs
Software compatibility analysis for quantitative measures of [18F]flutemetamol amyloid PET burden in mild cognitive impairment
Rationale: Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer’s disease pathogenesis. In clinical practice, trained readers will visually categorise positron emission tomography (PET) scans as either Aβ positive or negative. However, adjunct quantitative analysis is becoming more widely available, where regulatory approved software can currently generate metrics
Anterior cruciate ligament reconstruction improves subjective ability but not neuromuscular biomechanics during dynamic tasks
Purpose: The purpose of this study was to identify high-functioning anterior cruciate ligament-deficient patients and assess the effects of reconstruction on their self-reported functionality, muscle activations and biomechanical properties. Methods: Twenty young and active patients participated pre- (11.5 ± 14.3 months post-injury) and again 10.5 ± 1.7 months post-reconstruction and were individu
Making hot Jupiters in stellar clusters: The importance of binary exchange
It has been suggested that the occurrence rate of hot Jupiters (HJs) in open clusters might reach several per cent, significantly higher than that of the field (~a per cent). In a stellar cluster, when a planetary system scatters with a stellar binary, it may acquire a companion star, which may excite large-amplitude von Zeipel-Lidov-Kozai oscillations in the planet's orbital eccentricity, trigger