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United and divided : Early modern economic history in Finnish and Swedish academic literature

In this chapter, we analyze Finnish and Swedish economic history research on these countries’ common past (prior to 1809) and the early modern era (defined here as between 1500 and 1850). Using extensive bibliometric databases, we show that even when they focus on the early modern era, economic historians most often analyze Finland and Sweden in terms of their modern borders. Researchers based in

Testing Phenotypic Models of Posttraumatic Stress Disorder and Alcohol Use Disorder Comorbidity Using Longitudinal Registry Data

Objective: Two predominant phenotypic models of causality exist to explain the high co-occurrence of posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD): the self-medication and susceptibility models. Population-based longitudinal studies that simultaneously examine both models are needed. Thus, the goal of the pres-ent study is to test these models using the Swedish National Regis

A nordic multicenter study on contemporary outcomes of pediatric short bowel syndrome in 208 patients

Background & aims: Despite advances in the management of short bowel syndrome related intestinal failure (SBS-IF), large-scale contemporary pediatric studies are scarce. The aim of this multicenter study was to assess key outcomes and clinical prognostic factors in a recent Nordic pediatric SBS-IF population. Methods: Patients with SBS-IF treated during 2010–2019, whose parenteral support (PS)

Municipally Owned Corporations in Sweden

The use of municipally owned corporations (MOCs) has a long tradition in Sweden. In this chapter we take the point of departure in this long tradition of MOCs when describing how the use of these corporations has developed over time as well as the conditions under which these MOCs operate has developed. In addition, some of the more problematic features of MOCs, that Swedish local governments stru

Viral bodies: racialised and gendered logics in the securitisation of migration during COVID-19 in Italy

Since the spread of the COVID-19 pandemic, migrants’ mobility has been increasingly securitised as governments have been adopting extraordinary measures to close both external and internal borders. Similarly, the presence of migrants within countries has often been met with lower levels of acceptance, leading to the implementation of discriminatory and xenophobic measures. Although debates on the

Manual-free software for a technical instrument

In workplaces, a lot of knowledge is lost when colleagues change positions. What was once obvious to one person can be incomprehensible to the next. This problem has been encountered by Probation Labs Sweden AB with their biochemical instrument, Labbot. Labbot facilitates researchers in automating their protein analysis. It works like a multi-tool where users can perform one or several tasks in a

Two local minima for structures of [4Fe–4S] clusters obtained with density functional theory methods

[4Fe–4S] clusters are essential cofactors in many proteins involved in biological redox-active processes. Density functional theory (DFT) methods are widely used to study these clusters. Previous investigations have indicated that there exist two local minima for these clusters in proteins. We perform a detailed study of these minima in five proteins and two oxidation states, using combined quantu

Three concepts of globalization

This article is a brief inquiry into the meaning and function of the concept of globalization within the social sciences during the last decade. Describing the ontological presuppositions and historical trajectory of the concept of globalization, this article distinguishes three distinct senses of the idea - transference, transformation and transcendence - and argues that these senses have emerged

Exploring the Applications of Machine Learning in the Public Sector

Despite the many use cases for machine learning, it sees minimal usage in Sweden’s public sector today. It is important that the public sector in particular utilizes the most efficient tools available. For this reason, the Department of Employment and Social Services in Malmö has started a project to explore the viability of introducing machine learning to their work. This thesis corresponds to ro

Functional In Vivo Screening Identifies microRNAs Regulating Metastatic Dissemination of Prostate Cancer Cells to Bone Marrow

Distant metastasis is the major cause of cancer-related deaths in men with prostate cancer (PCa). An in vivo functional screen was used to identify microRNAs (miRNAs) regulating metastatic dissemination of PCa cells. PC3 cells transduced with pooled miRZiP™ lentivirus library (anti-miRNAs) were injected intraprostatic to 13 NSG mice followed by targeted barcode/anti-miR sequencing. PCa cells in th

The age-dependent association of Life's Simple 7 with transitions across cognitive states after age 60

Background: Life's Simple 7 (LS7) aims to promote ideal cardiovascular health (CVH). Its association with different cognitive states in the older old is unclear. Objectives: To assess the associations of LS7 with transitions across normal cognition, cognitive impairment, no dementia (CIND), and dementia and evaluate cognitive impairment-free years of life by LS7-defined CVH levels in older adults.

Particle Detection in Bone Marrow Using CNNs and Transformer Networks

The critical role of hematological stem cells, concentrated in bone marrow, in disease diagnosis makes the detection of these cells an imperative task. The current process, however, is slow and heavily reliant on expert interpretation, underscoring the need for automation. In this thesis, we collected a 20x microscopy dataset of real and fake bone marrow particles and fine-tuned several CNNs and T

A low-cost, long-running, open-source stereo camera for tracking aquatic species and their behaviours

Ecologists are now widely utilising video data to quantify the behaviours and interactions of animals in the wild. This process can be facilitated by collecting videos in stereo, which can provide information about animals' positions, movements and behaviours in three-dimensions (3D). However, there are no published designs that can collect underwater 3D stereo data at high spatial and temporal re

Urban Geopolitics and the Decentring of Migration Diplomacy in EU-Moroccan Affairs

In 2018, the International Organization for Migration stated that ‘migration has nearly become synonymous with urbanization, given the dominance of the city as the destination of most migrants’. The geopolitical dimension of migration governance is especially important in Mediterranean cities where the European Union’s (EU) efforts to push border management onto external actors has occurred alongs

Software compatibility analysis for quantitative measures of [18F]flutemetamol amyloid PET burden in mild cognitive impairment

Rationale: Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer’s disease pathogenesis. In clinical practice, trained readers will visually categorise positron emission tomography (PET) scans as either Aβ positive or negative. However, adjunct quantitative analysis is becoming more widely available, where regulatory approved software can currently generate metrics

Anterior cruciate ligament reconstruction improves subjective ability but not neuromuscular biomechanics during dynamic tasks

Purpose: The purpose of this study was to identify high-functioning anterior cruciate ligament-deficient patients and assess the effects of reconstruction on their self-reported functionality, muscle activations and biomechanical properties. Methods: Twenty young and active patients participated pre- (11.5 ± 14.3 months post-injury) and again 10.5 ± 1.7 months post-reconstruction and were individu

Making hot Jupiters in stellar clusters: The importance of binary exchange

It has been suggested that the occurrence rate of hot Jupiters (HJs) in open clusters might reach several per cent, significantly higher than that of the field (~a per cent). In a stellar cluster, when a planetary system scatters with a stellar binary, it may acquire a companion star, which may excite large-amplitude von Zeipel-Lidov-Kozai oscillations in the planet's orbital eccentricity, trigger