Background Medullary thyroid carcinoma is an aggressive tumor and presents with significant morbidity and mortality and a high rate of lymph node metastases. The combination of total thyroidectomy and cervical lymphadenectomy is the essential treatment for those patients presenting with cervical lymph node metastases. Materials and methods A retrospective analysis of 117 patients operated for medu

Effective control of endotoxins and bacteria is crucial for normal wound healing. During injury, the key enzyme thrombin is formed, leading to generation of fibrin. Here, we show that human neutrophil elastase cleaves thrombin, generating 11-kDa thrombin-derived C-terminal peptides (TCPs), which bind to and form amorphous amyloid-like aggregates with both bacterial lipopolysaccharide (LPS) and gra

Video capsule endoscopy (VCE) has become the method of choice for visualizing the small bowel mucosa and is generally considered to be a safe method. Although uncommon, the most feared complication of VCE is capsule retention that can potentially lead to life-threatening bowel obstruction. Herein, we present for the first time a case of capsule retention in a colonic stent. The patient had known C

Increased research is being driven by the automotive industry facing challenges, requiring to comply with both current and future emissions legislation, and to lower the fuel consumption. The reason for this legislation is to restrict the harmful pollution which every year causes 3.3 million premature deaths worldwide [1]. One factor that causes this pollution is NOx emissions. NOx emission legisl

Scrubbing is widely used in biomass gasification plants for tar removal. However, the cost of the scrubber liquid and its disposal once used can represent a non-negligible part of the plant operating cost. It is possible to lower this cost by regenerating and reusing the scrubber liquid by removing ash and heavy tars with the help of a centrifuge. Data from the two biomass gasification plants Hort

Computer-based design analysis is nowadays of utmost importance for most engineering design projects. However, this brings some challenges, among them that of the collaboration between engineering designers and design analysts. Since they work with, and are responsible for, different areas, they do not necessarily have full insight into each other’s way of working. The issue of integration between

Det är många maskiner och människor engagerade i en avverkning där man tar ut virke, grot och stubbar. En serie djupintervjuer med olika intressenter och aktörer visar att det finns stora brister i planering, logistik och kommunikation mellan de olika leden i kedjan, speciellt då flera olika entreprenörer är inblandade. Svaren visar också att det finns ett behov av bättre utbildning – och att man

Background: The prevalence of migraine with co-existing tension-type headache and neck pain is high in the general population. However, there is very little literature on the characteristics of these combined conditions. The aim of this study was to investigate a) the prevalence of migraine with co-existing tension-type headache and neck pain in a clinic-based sample, b) the level of physical acti

Histological grade is one of the most commonly used prognostic factors for patients diagnosed with breast cancer. However, conventional grading has proven technically challenging, and up to 60% of the tumors are classified as histological grade 2, which represents a heterogeneous cohort less informative for clinical decision making. In an attempt to study and extend the molecular puzzle of histoloHistological grade is one of the most commonly used prognostic factors for patients diagnosed with breast cancer. However, conventional grading has proven technically challenging, and up to 60% of the tumors are classified as histological grade 2, which represents a heterogeneous cohort less informative for clinical decision making. In an attempt to study and extend the molecular puzzle of histolo

BACKGROUND:Atrioventricular plane displacement (AVPD) is an indicator for systolic and diastolic function and accounts for 60% of the left ventricular, and 80% of the right ventricular stroke volume. AVPD is commonly measured clinically in echocardiography as mitral and tricuspid annular plane systolic excursion (MAPSE and TAPSE), but has not been applied widely in cardiovascular magnetic resonanc

We here describe two proteomic datasets deposited in ProteomeXchange via PRIDE partner repository [1] with dataset identifiers PXD000484 (defined as "training") and PXD000485 (defined as "test") that have been used for the development of a tamoxifen outcome predictive signature [2]. Both datasets comprised 56 fresh frozen estrogen receptor (ER) positive primary breast tumor specimens derived from

Decentralisation in Cambodia has long been propagated as a means to enhance local engagement with governance structures. But in the forestry sector, even limited devolution of powers often constrains local user groups with excessive bureaucratic burdens. In addition, entrenched political economy interests tend to inhibit effective governance. To investigate the apparent institutional malaise that

The solid oxide fuel cell (SOFC) is an electrochemical device that converts the chemical energy present in reactant fuels into electrical energy and heat. Such conversion is given by the electrochemical reactions that occur inside the fuel cells when the reactant gases reach the so-called Three-phase Boundary (TPB). However, before the reactant gases can reach the TPBs, they have to pass through a

Precarious employment has been associated with poor mental health. Moreover, increasing labour market precariousness may cause individuals to feel ‘locked-in’, in non-desired workplaces or occupations, out of fear of not finding a new employment. This could be experienced as a ‘loss of control’, with similar negative health consequences. It is plausible that the extent to which being in a non-desi

The evolution of family living is underpinned by conflict and cooperation between family members. While family groups can be maintained by reducing conflict between parents and offspring, interactions between siblings may play an equally important role. Here, we compared the level of aggressive interactions between siblings to that between parents and their offspring in the family living skink Lio