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Molecular detection of Borrelia burgdorferi sensu lato – An analytical comparison of real-time PCR protocols from five different Scandinavian laboratories
Introduction: Lyme borreliosis (LB) is the most common tick transmitted disease in Europe. The diagnosis of LB today is based on the patient´s medical history, clinical presentation and laboratory findings. The laboratory diagnostics are mainly based on antibody detection, but in certain conditions molecular detection by polymerase chain reaction (PCR) may serve as a complement. Aim: The purpose o
Effects of household washing on bacterial load and removal of Escherichia coli from lettuce and "ready-to-eat" salads
Customer demands for fresh salads are increasing, but leafy green vegetables have also been linked to food-borne illness due to pathogens such as Escherichia coli O157:H7. As a safety measure, consumers often wash leafy vegetables in water before consumption. In this study, we analyzed the efficiency of household washing to reduce the bacterial content. Romaine lettuce and ready-to-eat mixed salad
Humaniora i yrkeslivet
Usher syndrome : Pathogenesis, diagnosis and therapy
This book is just what we needed to gather the knowledge accumulated on Usher syndrome throughout the past fifteen years. The epidemiology and pathophysiology of the disease are discussed in several chapters. The great importance of an early diagnosis of the disease in affected children in order to provide them with appropriate education and therapeutic choices is suitably emphasized. Present ther
Physiopathology of retinal degeneration in rd1 mouse model of retinitis pigmentosa : TGF-Β1, proteinases and oxidative stress mechanisms
The rd1 (retinal degeneration) mouse retina shows degeneration homologous to a form of retinitis pigmentosa with a rapid loss of rod photoreceptors and deficiency of retinal blood vessels. Due to Pde6brd1 gene mutation, β subunit of phosphodiesterase (PDE) of rd1 retina has an inactive PDE which elevates cGMP and Ca2+ ions level. In vitro retinal explants provide a system close to the in vivo situ
Etik på svältkost. Varför blivande läkare och annan vårdpersonal behöver utökad undervisning i etik.
Vetenskap och beprövad erfarenhet - medicin
Patientsäkerhetslagen från 2014 säger att patienten ska få sakkunnig och omsorgsfull hälso- och sjukvård som är av god kvalitet och står i överensstämmelse med vetenskap och beprövad erfarenhet. Detta krav är på intet sätt nytt, det har formellt funnits sedan 1890-talet och går att spåra betydligt längre tillbaka i tiden. Formuleringen utgör en klassisk svensk begreppsbildning.Idag hittar vi samma
Mortality and the Business Cycle : Evidence from Individual and Aggregated Data
There has been much interest recently in the relationship between economic conditions and mortality, with some studies showing that mortality is pro-cyclical, while others find the opposite. Some suggest that the aggregation level of analysis (e.g. individual vs. regional) matters. We use both individual and aggregated data on a sample of 20-64 year-old Swedish men from 1993 to 2007. Our results s
Changes, Problems, and Challenges in Swedish Spatial Planning—An Analysis of Power Dynamics
During the past few decades, the Swedish spatial planning system has experienced numerous problems and challenges. In particular, there have been changes in legislation and an increased neoliberalisation of planning that gives private actors a larger influence over the planning processes in Sweden. In this article, we analyse these changes through the lenses of collaborative and neoliberal planninDuring the past few decades, the Swedish spatial planning system has experienced numerous problems and challenges. In particular, there have been changes in legislation and an increased neoliberalisation of planning that gives private actors a larger influence over the planning processes in Sweden. In this article, we analyse these changes through the lenses of collaborative and neoliberal plannin
The Establishment of Genetic Counselling in Sweden : 1940–1980
Genetic counselling in Sweden may be traced to the eugenics movementin the early twentieth century. A rudimentary form of what we might call geneticcounselling today was practised within the state governed Medical Board in the1940s and 1950s by the scientific advisor Nils von Hofsten. In the 1950s, Jan ArvidBöök, professor of medical genetics at Uppsala University, realised the importanceof studie
A post-mortem analysis of China's township elections
Retorikens grunder
Forskning och framtid : Ett historiskt perspektiv
Forskningspolitisk aktör och vetenskaplig institutionsbyggare : Arne Tiselius och etableringen av molekylärbiologin i Sverige
Genetisk rådgivning : risker, ansvar och individuell autonomi
Genetisk rådgivning (vägledning) etablerades inom svensk sjukvård under 1960- och 1970-talet. Samtidigt stärktes föreställningen om individens självbestämmande i reproduktiva frågor, en uppfattning som hade börjat formuleras redan under 1950-talet. I artikeln diskuteras hur den genetiska rådgivningen som tidigare baserats på empiriska riskberäkningar under 1960- och 1970-talet fick en delvis annanGenetic counseling was established within the Swedish healthcare system in the 1960s and 1970s. During this period the idea of individual autonomy, which had been introduced into genetic counseling already in the 1950s, was gradually strengthened. The paper discusses the development of medical knowledge and technologies related to heredity during this period, from empi-rical risk calculations to t