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Objective To compare the antenatal detection rate of malformations in chromosomally normal fetuses between a strategy of offering one routine ultrasound examination at 12 gestational weeks (gws) and a strategy of offering one routine examination at 18 gws. Design Randomised controlled trial. Setting Multicentre trial including eight hospitals. Population A total of 39 572 unselected pregnant women

Popular AbstractInnovation, skapandet av nya produkter och processer, är i hög grad ojämnt fördelat över det geografiska rummet. Denna ojämna fördelning har stor betydelse för regionala ekonomiers relativa framgång. Geografiskt koncentrerat kunskapsutbyte mellan företag och andra organisationer är många gånger avgörande för dessa aktörers sammanlagda innovativa kapacitet, och därmed för regionens Innovation, the act and outcome of making something novel, is unevenly distributed across the geographical landscape. This uneven distribution has a profound impact on the differential success of regional economies. Localized learning between co-located firms and organizations provides an important source of increased innovation for regions to face challenges posed by increasingly global competiti

Proteomics studies rely on high-resolving separation techniques whereby the biological complexity can be unraveled. Both gel-based and liquid-phase separation principles are needed in order to mine deeper into the low abundant area of the proteins expressed in human cell samples. The expression levels that can be reached today with proteomics technology are still only reaching part of all proteins

Temperature is a fundamental thermodynamic parameter used to describe physical, chemical and biological processes. Much effort is made to measure temperature accurately in a wide variety of applications, making temperature one of the most extensively measured parameters. In combustion as in many other applications, temperature plays a substantial role in helping to maintain an efficient and clean

Poland, as many other countries, has ambitions to increase the use of renewable energy sources. In this paper, we review the current status of bioenergy in Poland and make a critical assessment of the prospects for increasing the share of bioenergy in energy supply, including policy implications. Bioenergy use was about 4% (165PJ) of primary energy use (3900PJ) and 95% of renewable energy use (174

Andrena humilis is an endangered oligolectic solitary bee and has declined in recent decades throughout western Europe. The aim of this study was to explore the pollen harvesting pattern and to determine the reproductive rate in specialized andrenid bees. We measured the amount of pollen required to produce one brood-cell, the pollen harvesting rate and compared our results with data for other spe

BACKGROUND AND PURPOSE: MR imaging has made it easier to distinguish among the different types of intracranial mass lesions. Nevertheless, it is sometimes impossible to base a diagnosis solely on clinical and neuroradiologic findings, and, in these cases, biopsy must be performed. The purpose of this study was to evaluate the hypothesis that proton MR spectroscopy is able to improve preoperative d

This article contrasts two fundamentally world-economy. The article begins by sketching different understandings of economic growth the history of these two perspectives in recent and “development” that lead to diametrically decades and reflecting on the ideological and opposed approaches to how to deal with epistemological contexts of their appearance global ecological deterioration. One is the a

We recently described a novel chemoattractant receptor, provisionally named CMKRL1, which has turned out to be the first cloned leukotriene (LT) receptor. Present binding assays using tritiated LTB4 and isolated membranes from COS-7 cells, transiently transfected with cDNA encoding this receptor, yielded a linear Scatchard plot showing expression of only a single, high-affinity receptor population

Intensive use of the benchmark simulation model No. 1 (BSM1), a protocol for objective comparison of the effectiveness of control strategies in biological nitrogen removal activated sludge plants, has also revealed a number of limitations. Preliminary definitions of the long-term benchmark simulation model No. 1 (BSM1_LT) and the benchmark simulation model No. 2 (BSM2) have been made to extend BSM

In this paper we address the problem of estimating the mean derivative when the entity containing the parameter has jumps. The methods considered are finite differences, infinitesimal perturbation analysis and the likelihood ratio score function. We calculate the difference between the differentiated mean and the mean derivative. In case of finite differences, we compute the stepsize in the simula