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Demographics, injury characteristics and outcome of traumatic brain injuries in northern Sweden

Objectives - To describe demographics, injury characteristics and outcome of traumatic brain injury (TBI) in northern Sweden over 10 years. Materials and methods - Data were retrospectively collected on those individuals (n = 332) in Norrbotten, northern Sweden, with a TBI who had been transferred for neurosurgical care from 1992 to 2001. Results - A majority were older men with a mild TBI and an

Using computer simulation to assist in the robustness analysis of an ion-exchange chromatography step

This paper presents a methodology to gain process knowledge and assist in the robustness analysis of an ion-exchange step in a protein purification process using a model-based approach. Factorial experimental design is common practice in industry today to obtain robustness characterization of unit operations with respect to variations in process parameters. This work aims at providing a better ins

Svenskhet, katolicism och europeisk integration : Katolska kyrkan i Sverige efter 1945

Under de senaste femtio åren har den katolska kyrkans ställning i Sverige radikalt förändrats. Fortfarande i början av 1960-talet betraktades katolicismen allmänt som ett hot mot det svenska samhället och mot svensk kulturell identitet, inte minst inom den svenska socialdemokratin. Idag är katolska kyrkan en accepterad del av det svenska samhället. I min artikel diskuterar jag denna förändringsproThe position of the Catholic Church in Sweden has radically changed in the last forty years. At the beginning of the 1960s, Catholicism was commonly regarded as a threat to Swedish cultural identity, not least among members of the ruling Social-Democratic Party. Today, the Catholic Church is an accepted part of Swedish society. In my article, I discuss this process ofchange and its impact on Swedi

Molecular structure and interaction of recombinant human type XVI collagen

Collagen XVI is a minor component of at least two different extracellular fibrillar networks of specialized regions of skin and cartilage. In skin, collagen XVI is integrated into particular fibrillin-rich microfibrils lacking an amorphous elastin core. In cartilage, collagen XVI is a component of small heterotypic D-banded fibrils, mainly occurring in the territorial matrix of chondrocytes. Here,

Increased store-operated Ca2+ entry into contractile vascular smooth muscle following organ culture

Ca2+ inflow via store-operated Ca2+ channels was investigated in rings of rat tail and basilar arteries kept in serum-free organ culture, which is known to preserve the contractility of the vascular smooth muscle. After culture for 3-4 days, Ca2+ release from intracellular stores in response to caffeine (20 mM) was augmented 2- to 4-fold. Following depletion of intracellular Ca2+ stores by caffein

Emissions from baled municipal solid waste: II. Effects of different treatments and baling techniques on the emission of volatile organic compounds

This paper focuses on the volatile organic compound emissions from baled municipal solid waste (MSW). The analytical methodology was based on sampling with adsorbent tubes once a month during seven occasions within a time period of 1 year. Automated analyses were carried Out on-line work-up with thermal desorption directly connected to a gas chromatograph-mass spectrometer. The effect of different

Kliniska kriterier bästa stöd för diagnosen lätt till måttlig artros. Symtomen, inte röntgenundersökningen, styr valet av behandling

No generally accepted definition of osteoarthritis exists. Traditionally, the diagnosis is obtained by radiographic examination but different definitions are used for different purposes. Since no causal treatment exists, treatment is aiming at reducing symptoms and improving function. The correlation between radiographic features of osteoarthritis and symptoms is poor. Thus, it is recommended that

Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway.

Boswellic acids are the compounds isolated from the gum resin of Boswellia serrata and have been used for the treatment of inflammatory diseases for many years in the countries of the east. Recently, a few studies showed that the acids may have anti-cancer effect on leukemia and brain tumours. We investigated the apoptotic and anti-proliferative effects of two types of boswellic acids, keto-beta-b

Action spectra for conversions of phycochrome c from Nostoc-muscorum

The reversibly photochromic pigment, phycochrome c, was extracted from the blue-green alga Nostoc muscorum strain A. Action spectra were determined for in vitro conversions of the pigment from the short wavelength to the long wavelength form and vice versa. The action peak for the absorbance decrease at 650 nm is at 630 nm. During this decrease there is only a slight increase of the absorbance in