The Insulin-like Growth Factor (IGF)-related system is implicated in neuroregeneration and cell repair, as well as regulating lifespan. IGF-II, one component of this system, has also been found to affect memory functions in a rat model. In this study we explored changes in the IGF-related system in patients with Alzheimer's disease (AD), including changes in IGF-II levels.

The broad aim of this thesis is to explain the fundamental themes and function of Swedish field sermons and field prayers, and so to re-examine the view in earlier research that field sermons were primarily ‘Old Testamentary’ in nature. Inspired by more recent international research, I hold that the sermons’ basic functions were twofold: discipline and comfort. What matters, is to understand the d

Ethnic discrimination in the criminal justice system is a well-researched topic, but the significance of ethnicity in policing activities at more mundane levels has attracted less attention. This article analyzes ethnographic data on municipal ‘safety work’ in a Swedish city troubled with robberies, vandalism, and violence. It shows how the efforts of different safety workers, operating to curb cr

Leptin is an adipocyte-secreted hormone, the circulating levels of which correlate closely with overall adiposity. Although rare mutations in the leptin (LEP) gene are well known to cause leptin deficiency and severe obesity, no common loci regulating circulating leptin levels have been uncovered. Therefore, we performed a genome-wide association study (GWAS) of circulating leptin levels from 32,1

Recent developments in extremum seeking theory have established a general framework for the methodology, although the specific implementations, particularly in the context of multi-agent systems, have not been demonstrated. In this work, a group of sensor-enabled vehicles is used in the context of the extremum seeking problem using both local and global optimisation algorithms to locate the extrem

We analyze a coincidence Stem-Gerlach measurement often discussed in connection with the derivation and illustration of Bell's theorem. The treatment is based on our recent analysis of the original Stern-Gerlach experiment [H. Wennerstrom and P.-O. Westlund, Phys. Chem. Chem. Phys. 14, 1677 (2012)1, where it is concluded that it is necessary to include a spin relaxation process to account for the

Background When acute coronary syndrome (ACS) cannot be ruled out, emergency department (ED) patients with chest pain are admitted for in-hospital observation because of the risk of complications such as arrhythmia and acute heart failure. A study was undertaken to compare the ability of three risk prediction models to identify patients at a very low risk of complications. Methods 559 consecutive

Radial velocities measured from near-infrared (NIR) spectra are a potentially powerful tool to search for planets around cool stars and sub-stellar objects. However, no technique currently exists that yields NIR radial velocity precision comparable to that routinely obtained in the visible. We are carrying out an NIR radial velocity planet search program targeting a sample of the lowest-mass M dwa

A rotating target consisting of helium-cooled tungsten has been chosen for the European Spallation Source (ESS) facility to be built in Lund. Thermo-mechanical cycling due to the incidence of the proton beam every 2 s on any given tungsten slab in the rotating wheel could lead to crack formation and failure over the lifetime of the target. This work reports tensile and fatigue data obtained at roo

There are two theories that attempt to explain how attention is deployed when lines are traced. Initially, it was believed that a covert zoom lens moved along the line. Recent evidence has, however, suggested that attention spreads along the line, rather than moving along it, perhaps as part of an effortful object-parsing process. Three experiments tested the spreading and moving accounts of line

In this paper we argue that the emergence of the dominant model of university organization, which is characterized by a large agglomeration of many (often loosely affiliated) small research groups, might have an economic explanation that relates to the features of the scientific production process. In particular, we argue that there are decreasing returns to scale on the level of the individual re

This paper challenges the idea that emissions of greenhouse gases simply increase over time with income. It adopts a 200-year perspective and includes the important flows of greenhouse gases related to agriculture, not just the CO2 from fossil fuels. The result is that the pattern of Swedish total greenhouse gas emissions over time resembles an N. In contrast, when only emissions from fossil fuels

Background The Chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) blocks the Complement fragment C5a receptor (C5aR) and formylated peptide receptor (FPR) and is thereby a potent inhibitor of neutrophil chemotaxis and activation of inflammatory responses. The majority of the healthy human population has antibodies against CHIPS that have been shown to interfere with its function in vit

For some time it has been argued that cities all over the world have become more entrepreneurial and increasingly competitive. Most research has focused on spectacular events in well-known metropolises, but far less is known about how smaller cities engage in competitive activities. This paper focuses on how, why and what Swedish cities hope to achieve by engaging themselves in hosting the tryouts

Abstract in Danish Som regel forstår vi demokrati og diktatur som to adskilte regeringsformer. Faktisk er de sammenflettede grundet undtagelsestilstanden og dens uundgåelighed i den politiske forfatning. Denne indrømmelse befrier os fra normativ forudindtagethed om det politiske og leder os til den hypotese at hvis vi studerer det politiske hinsides ideologiske spilfægterier og narrative konstruktNormally, we understand democracy and dictatorship as two separate forms of government. Actually, they are intertwined due to the state of exception and its inevitability for the political constitution. This concession frees of normative pre-conceptions of the political and leads us to the hypothesis that if we study the political beyond ideological skirmishes and narrative constructions we can co

The Centre party weathered what amounted to an almost existential mid-term public opinion crisis, to end up outperforming its coalition partners in the 2014 general election. Although it too fell back, it shed a notable proportion of tactical support voters, and actually increased its share of genuine, first-preference, voters. The Centre party has revisited and refreshed its ideological foundatio

Elastic scattering of photons from C-12 has been investigated using quasimonoenergetic tagged photons with energies in the range 65-115 MeV at laboratory angles of 60 degrees, 120 degrees, and 150 degrees. at the Tagged-Photon Facility at the MAX IV Laboratory in Lund, Sweden. A phenomenological model was employed to provide an estimate of the sensitivity of the C-12(gamma,gamma)C-12 cross section