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On being dependent on home mechanical ventilation : Depictions of patients' experiences over time

In this study, the authors describe the meanings of experiences of being dependent on a ventilator (HMV) and living at home as narrated by 13 people who had been using a ventilator via a mask or tracheostomy for half a year. The analyses revealed various movements across time toward the goal of using the ventilator successfully, and some narratives depicted suffering caused by care. The analyses a

Clinical group supervision in an intensive care unit : A space for relief, and for sharing emotions and experiences of care

Much has been written about models, aims and the concept of clinical group supervisional, although few studies are empirical or focus on intensive care. • The aim of the study was to illuminate the process and describe, using qualitative content analysis, the content of conversations carried out during the course of clinical group supervision sessions among Registered Nurses (RN) and enrolled nurs

Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats

Maternal hypoglycaemia throughout gestation until gestation day (GD)20 delays foetal growth and skeletal development. While partially prevented by return to normoglycaemia after completed organogenesis (GD17), underlying mechanisms are not fully understood. Here, we investigated the pathogenesis of these changes and significance of maternal hypoglycaemia extending beyond organogenesis in non-diabe

Repeatability of pheromone emissions from individual female ermine moths Yponomeuta padellus and Yponomeuta rorellus

The repeatability of the composition of pheromone emitted by individual female moths (Yponomeuta) was determined by gas Chromatographic analysis. An improved technique for repeated collections of airborne volatiles from the same moth was developed. The procedure did not harm the females and allowed precise quantification of 0.05 ng of pheromone components in 30-min collections. Individual females

Intake of Lactiplantibacillus plantarum HEAL9 reduces the inflammatory markers soluble fractalkine and CD163 during acute stress : A randomized, double blind, placebo-controlled study

The intestine and the brain are connected via the brain-gut axis and the intestinal microbiota influences the immune activation and signaling molecules that are involved in the stress response. The aim of the study was to investigate if intake of the probiotic strain Lactiplantibacillus plantarum HEAL9 (LPHEAL9) for four weeks could counteract elevated cortisol and inflammation levels in subjects

The need of latent variables for modelling decision-making in evacuation simulations

Evacuation models generally tend to make over-simplifications in the representation of human behaviour in fire due to the difficulties to capture its complexity. This work shows how ‘new’ discrete choice model approaches allow overcoming this issue. A description of the existing state-of-the-art of discrete choice models is introduced to highlight the potential of those models. Three case studies

Erosion of planetesimals by gas flow

The first stages of planet formation take place in protoplanetary disks that are largely made up of gas. Understanding how the gas affects planetesimals in the protoplanetary disk is therefore essential. In this paper, we discuss whether or not gas flow can erode planetesimals. We estimated how much shear stress is exerted onto the planetesimal surface by the gas as a function of disk and planetes

Foreign demand for agricultural commodities drives virtual carbon exports from Cambodia

Rapid deforestation is a major sustainability challenge, partly as the loss of carbon sinks exacerbates global climate change. In Cambodia, more than 13% of the total land area has been contracted out to foreign and domestic agribusinesses in the form of economic land concessions, causing rapid large-scale land use change and deforestation. Additionally, the distant drivers of local and global env

Under-reported relationship: a comparative study of pharmaceutical industry and patient organisation payment disclosures in the UK (2012-2016)

Objectives To examine the under-reporting of pharmaceutical company payments to patient organisations by donors and recipients. Design Comparative descriptive analysis of payments disclosed on drug company and charity regulator websites. Setting UK. Participants 87 donors (drug companies) and 425 recipients (patient organisations) reporting payments in 2012-2016. Main outcome measures. Number and

Granzyme B-mediated damage of CD8+ T cells impairs graft-versus-tumor effect

Allogeneic hematopoietic cell transplantation is an established treatment for hematologic and other malignancies. Donor-derived immune cells can identify and attack host tumor cells, producing a graft-versus-tumor (GVT) effect that is crucial to the treatment. Using multiple tumor models and diverse donor-host combinations, we have studied the role of granzyme B (GzmB) in GVT effect. We first conf

Rapid analysis methods for paralytic shellfish poisoning toxins (PSTs) monitoring in raw waters

The presence of paralytic shellfish poisoning toxins (PSTs) in drinking water resources has urged the development of simple and fast screening tools for drinking water surveillance. This article aims to validatea quick test kit for freshwater PSTs detection. Preliminary estimates of the limit of detection (LODs)were done for 5 PSPs variants, namely C1 toxin (a “C” toxin); GTX5(a Gonyautoxin); and

Hetero-nuclear STEAM: Localisation of 13C MR-spectroscopy using {1H-13C} polarisation transfer and 1D phase encoding

Abstrakt. Gradientval av överföringar gör det möjligt att förenkla polarisationsöverföringssekvenser genom att utelämna kemiska skift-återfokuseringspulser. Funktionerna hos en förenklad STEM-sekvens med tre pulser för {1H-13C} polarisationsöverföring har studerats vid 2 Tesla på ett helkropps MR-system med avseende på användning av MR-spektroskopi in vivo. Den observerade signalen ökas genom nett