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Heritability and genetic variance of dementia with Lewy bodies

Recent large-scale genetic studies have allowed for the first glimpse of the effects of common genetic variability in dementia with Lewy bodies (DLB), identifying risk variants with appreciable effect sizes. However, it is currently well established that a substantial portion of the genetic heritable component of complex traits is not captured by genome-wide significant SNPs. To overcome this issu

Creativity as a matter of context. : On the assessment of creativity and originality in artistic higher education.

In education programs with an artistic ground, i.e. where the student is supposed to develop an artistic skill, the overall objective is to provide the fundament for a practitioner to become a well functioning individual in a specific artistic community. This artistic community of practice plays – directly through professionally active teachers, and indirectly through teachers with a good understa

ERP studies of visual and auditory processing of negated sentences

In two event-related potential studies, we investigated the processing of sentences with prefixal negation (unauthorized), sentential negation (not authorized) and no negation (authorized). We asked whether prefixal and sentential negation resulted in delayed processing. In Experiment 1, sentences such as “The White House announced that the new Obama biography was authorized/unauthorized/not autho

Sexual orientation, suicide ideation and suicide attempt : A population-based study

The aim is to investigate associations between sexual orientation and experience of suicide thoughts and suicide attempts. The 2012 public health survey in Scania, southern Sweden, is a cross-sectional population-based study including 28,029 participants aged 18–80 with 51.7% participation. The associations between sexual orientation and experience of suicide thoughts and attempts were investigate

Postoperative complications following colonic resection for cancer are associated with impaired long-term survival

Aim: Surgery for colorectal cancer is associated with a high incidence of postoperative complications. The aim of this study was to analyse whether postoperative complications following radical resection for colorectal cancer are associated with increased recurrence rate and impaired survival. Method: Patients operated for colon cancer between 2007 and 2009 with curative intent were identified thr

The impact of parental death on the timing of first marriage: Evolutionary versus social explanations (The Netherlands, 1850–1940)

Background: This article examines the impact of parental death in childhood, adolescence, and adulthood on male and female age at marriage in the Netherlands in the period 1850–1940. It follows an interdisciplinary approach as it considers explanations based on social and demographic history and evolutionary biology.Objective: We study the classical historical framework in more detail by controlli

Evidence for molecular structural variations in the cytoarchitectures of a Jurassic plant

In this study, we investigate the molecular structural characteristics of organic remains in various cellular organelles from a 180 Ma Jurassic royal fern belonging to the Osmundaceae family of ferns, and compare their carbon isotopic compositions to a now-living species of royal fern (Osmunda regalis). We discovered molecular structural variations indicated by Raman and infrared spectral paramet

Investigation of self-reported dizziness in the elderly when lying down or turning over in bed, and possible benign paroxysmal positional vertigo

ObjectivesThis study aimed to investigate the rate of dizziness and occurrence of benign paroxysmal positional vertigo in the elderly by physical examination in those reporting dizziness symptoms when lying down or turning over in bed.MethodsA total of 498 people, aged 70-85 years, were asked to complete a questionnaire regarding dizziness symptoms. Subjects answering that they became dizzy in bed

Impact of water drop presence on diffusion parameters of PEFC gas diffusion layers

A polymer electrolyte fuel cell (PEFC) produces electrical energy thanks to the electrochemical reaction carried out inside the cell. During the energy conversion, water molecules are also produced in the cathode side and this can affect the diffusion parameters of the gas diffusion layers (GDLs). The generated water-drops due to the reaction may block the reactant gases and produce material oxida

Regulating European Standardisation through Law : The Interplay between Harmonised European Standards and EU Law

Standardisation is one of the oldest human activities. Industrial revolution and electro-technical advancements have further increased the importance of standardisation. Nowadays standards regulate our daily life not only through the products and services we use, but also directly as laws. In the EU, Harmonised European Standards (HESs) are used in legislation—occupying the law’s domain—but at the

Simultaneous Growth of Pure Wurtzite and Zinc Blende Nanowires

The opportunity to engineer III-V nanowires in wurtzite and zinc blende crystal structure allows for exploring properties not conventionally available in the bulk form as well as opening the opportunity for use of additional degrees of freedom in device fabrication. However, the fundamental understanding of the nature of polytypism in III-V nanowire growth is still lacking key ingredients to be ab

Optimal Performance of Advanced Radiating Structures

Requirements on radiating structures are constantly increasing, demand for faster speed, smaller size, and higher reliability drives today's technical development. However, for electrically small structures, less than half-a-wavelength in size, performance is fundamentally limited by physical size. This thesis explores how to construct and calculate physical bounds for advanced antennas and comple