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Nanoparticles as pseudostationary phase in capillary electrochrornatography/ESI-MS

A novel technique that uses polymer nanoparticles as pseudostationary phase in capillary electrochromatography with electrospray ionization mass spectrometry detection is described. A continuous full filling technique in which the nanoparticles were suspended in the entire electrolyte volume as well as a conventional partial filling technique is presented. No nanoparticles entered the mass spectro

The evolution of Holocene coastal dunefields, Jutland, Denmark: A record of climate change over the past 5000 years

Coastal dunefields have developed on the west coast of Jutland in Denmark over the past 5000 years. The dunefields are situated in a temperate climate zone with frequent high energy wind events. Dunefield development was characterized by repeated periods of transgressive dune formation punctuated by periods of dune stabilization and soil formation. The chronology of dunefield evolution is based on

Mechanical design of the recirculating, terminal pumping in the Lund Pelletron, and experimental experience

A recirculating terminal pumping system has been installed in the 3 MV Pelletron tandem accelerator in Lund. An extremly limited space in the high voltage terminal and the absence of electrical power in the terminal, forced us to provide a unique design for the installation and powering of the new pumps. Details of the technical design, as well as experience of the use of the new system for accele

Characterisation of cell damage and death in embryonic mesencephalic tissue: a study on ultrastructure, vital stains and protease activity.

Dissociated embryonic ventral mesencephalic tissue is a source of dopaminergic neurones in both cell culture and neural transplantation studies. Around 90% of grafted dopaminergic neurones die within 1 week after transplantation. Little is known about when the cell death is triggered and what forms of cell death predominate. Using electron microscopy, we characterised ultrastructural changes in di

Resource availability affects investment in carnivory in Drosera rotundifolia

Carnivory in plants is restricted to nutrient-poor and open habitats presumably because of high benefits and/or low costs of carnivory in these conditions. Carnivory is costly because the plants need specific adaptations to capture prey. Drosera rotundifolia produces sticky substances on its leaf surface to catch prey. These substances are primarily carbon-based, and their production can be expect

Identification of two protein-binding and functional regions of curli, a surface organelle and virulence determinant of Escherichia coli

Curli are surface organelles of Escherichia coli. These fibrous proteins, formed by polymerization of a 15-kDa subunit, are expressed by E. coli strains associated with severe infections in humans. A remarkable property of curli is their ability to interact with a wide range of human proteins, interactions that contribute to the enhanced virulence of curli-expressing E. coli. To define the protein

Unexpected early extinction of the European pond turtle (Emys orbicularis) in Sweden and climatic impact on its Holocene range

Using ancient DNA sequences of subfossil European pond turtles (Emys orbicularis) from Britain, Central and North Europe and accelerator mass spectrometry radiocarbon dating for turtle remains from most Swedish sites, we provide evidence for a Holocene range expansion of the pond turtle from the southeastern Balkans into Britain, Central Europe and Scandinavia, according to the 'grasshopper patter

Carbohydrate functionalization using cationic iron carbonyl complexes

Cationic iron carbonyl cyclohexadiene complexes were employed in the derivatization of the 3-OH position of unprotected and protected methyl beta-D-galactopyranosides using two different approaches, giving access to galactopyranosides with an aromatic or cyclohexadienoic functionality in this position. (c) 2008 Elsevier Ltd. All rights reserved.

Expression pattern of apolipoprotein M during mouse and human embryogenesis

Apolipoprotein M (apoM) is a recently discovered human apolipoprotein predominantly present in high-density lipoprotein (HDL), and in minor proportions in triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). The gene encoding apoM is present in all mammalian genomes. The identity of the apoM gene of human, rat and mouse is over 80%. However, the (patho)physiological functions o

The objective diagnosis of vibration-induced vascular injury

For 44 patients with vibration-induced white finger and a reference group of 25 healthy men, finger systolic blood pressure (FSBP) before and after local cooling, skin temperature, and rewarming rates were determined before and after vasodilation (body warming and alcohol). An estimation of the proportions of vasopasm and organic changes was possible, and cutaneous changes could be separated from

How can a work rehabilitation process be improved? A qualitative study from the perspective of social insurance officers

The aim of this study was to describe social insurance officers experiences of a work rehabilitation process at a rehabilitation centre in the northern part of Sweden. Ten social insurance officers were interviewed about their experiences of a work rehabilitation process in general. The interviews were analysed by content analyses. The results showed that the experiences of how a rehabilitation pr

Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: an update

Women with a mutation in BRCA1 or BRCA2 face a lifetime risk of breast cancer of similar to 80%, and following the first diagnosis the 10-year risk of contralateral breast cancer is similar to 30%. It has been shown that both tamoxifen and oophorectomy prevent contralateral breast cancer, but it is not clear whether there is a benefit in giving tamoxifen to women who have previously undergone an o

Interaction of octaethylene glycol n-dodecyl monoether with dioctadecyldimethylammonium bromide and chloride vesicles

Several different methods were used to investigate the vesicle-to-micelle transition induced by the addition of the nonionic surfactant octaethylene glycol n-dodecyl monoether (C12E8) to spontaneously formed vesicle dispersions of dioctadecyldimethylammonium bromide and chloride (DODAX, X = Cl- and Br-). Dynamic light scattering reveals that fast mode micelles are formed upon addition of C12E6. Th

Nanowire-based multiple quantum dot memory

The authors propose and demonstrate an alternative memory concept in which a storage island is connected to a nanowire containing a stack of nine InAs quantum dots, each separated by thin InP tunnel barriers. Transport through the quantum dot structure is suppressed for a particular biasing window due to misalignment of the energy levels. This leads to hysteresis in the charging/discharging of the

Solid-state computerized manometry improves diagnostic yield in pharyngeal dysphagia: simultaneous videoradiography and manometry in dysphagia patients with normal barium swallows

OBJECTIVE: Dynamic barium radiology with cine- or video recording has been the most frequently used technique for assessing patients with pharyngeal dysphagia. Although the diagnostic yield of the barium swallow has been high, many patients with pharyngeal dysphagia have normal dynamic barium radiology and remain a diagnostic dilemma. Could manometry add important diagnostic information in these p

Guiding of Relativistic Electron Beams in Solid Targets by Resistively Controlled Magnetic Fields

Guided transport of a relativistic electron beam in solid is achieved experimentally by exploiting the strong magnetic fields created at the interface of two metals of different electrical resistivities. This is of substantial relevance to the Fast Ignitor approach to fusion energy production [M. Tabak et al., Phys. Plasmas 12, 057305 (2005)], since it allows the electron deposition to be spatiall

Comparison between a cognitive behavioural alcohol programme and post-mailed minimal intervention in high-risk drinking university freshmen: results from a randomized controlled trial.

Aim: Examine the effect of a 10 h intervention programme compared with post-mailed minimal intervention (PMMI) given to high-risk alcohol-drinking university freshmen in a random design. Method: In total 693 freshmen at the Lund Institute of Technology, Lund University, Sweden were included in the study. A cognitive behavioural alcohol program (CBAP) or PMMI was given to high-risk drinking freshme

Is Phosphorus Hesperus?

It is argued that philosophers who adopt the perdurance theory of persistence and who subscribe to the principle of Unrestricted Mereological Composition (UMC) are in a position to regard "Phosphorus is Hesperus'' as false.

Design and baseline characteristics of the simvastatin and ezetimibe in aortic stenosis (SEAS) study

Aortic valve stenosis and, atherosclerotic disease have several risk factors in common, in particular, hypercholesterolemia. Histologically, the diseased valves appear to have areas of inflammation much like atherosclerotic plaques. The effect of lipid-lowering therapy on the progression of aortic stenosis (AS) is unclear, and there are no randomized treatment trials evaluating cardiovascular morb