The Cochrun-Grabel (C-G) method, an algorithm for finding the characteristic polynomial of a circuit containing reactances, has so far been restricted to circuits not employing mutual inductances. In this paper we present an intuitive, yet rigorous, proof of the Cochrun-Grabel method for a general RLC circuit, and we extend the method to allow the analysis of an RLC circuit containing mutual induc

Expressions are derived for photoemission, which allow experimental electron energy loss data to be used for estimating losses in photoemission. The derivation builds on new results for dielectric response and mean free paths of strongly correlated systems of two-dimensional layers. Numerical evaluations are made for Bi2Sr2CaCu2O8 (Bi2212) by using a parametrized loss function. The mean free path

OBJECTIVES: To investigate the incidence and outcomes of acute lower gastrointestinal bleeding (ALGIB) in a population-based setting and examine the role of drugs potentially associated with GIB. METHODS: The study was prospective and population based. The cohort included all patients who underwent colonoscopy during the year 2010 at the National University Hospital of Iceland. Indications for

α1-antitrypsin (AAT) is a serine protease inhibitor, which recently has been shown to prevent type 1 diabetes (T1D) development, to prolong islet allograft survival and to inhibit β-cell apoptosis in vivo. It has also been reported that T1D patients have significantly lower plasma concentrations of AAT suggesting the potential role of AAT in the pathogenesis of T1D. We have investigated whether pl

BACKGROUND: Type 2 diabetes (T2D) is a complex disorder that is affected by multiple genetic and environmental factors. Extensive efforts have been made to identify the disease-affecting genes to better understand the disease pathogenesis, find new targets for clinical therapy, and allow prediction of disease. CONTENT: Our knowledge about the genes involved in disease pathogenesis has increased su

In the context of global R&D, we connect literature on knowledge management to a network-based theoretical framework helpful to analyse and explain the impact of globalisation of R&D on innovation performance. This framework is applied to two case companies, both global leaders within their respective industries, in order to analyse the extent to which their strategic globalisation of R&am

Raised plasma levels of the soluble urokinase plasminogen activator receptor (suPAR) have been associated with increased incidence of cardiovascular diseases. Whether suPAR is associated with venous thromboembolism (VTE) is largely unknown. The purpose of the present study was to investigate the relationship between suPAR and incidence of VTE in a cohort study. suPAR was measured in 5,203 subjects

Drug therapy is often directed to specific organ and tissue compartments where the mode of action of the compound effects specifically targeted biological processes. However, the direct measurement of drug uptake in terms of a time kinetic and concentrations attained at the local sites has not been readily available as a clinical index for most drugs. A proof-of-principle study was conducted to te

Summary. Physical activity has been considered as an important factor for bone density and as a factor facilitating prevention of osteoporosis. Bone density has been reported to be reduced in haemophilia. To examine the relation between different aspects of physical activity and bone mineral density (BMD) in patients with severe haemophilia on long-term prophylaxis. The study group consisted of 38

The ancient Egyptian site of Gebel el Silsila is known for its many pharaonic stelai, funerary shrines and the famous rock-cut chapel of Pharaoh Horemheb, but this article leaves the Pharaohs’ chronicles and explores instead a complex and mysterious marking system that is preserved as engravings in the site’s extensive quarries that run on both sides of the Nile. Here we will investigate Graeco-Ro

Innehållet i denna paper är i stort detsamma som i papern publicerad i Philologica Jassyensia 2008, men föredraget vid denna konferens insisterar mer på hur vi har „byggt upp” olika studieaktiviteter i den virtuella miljön för att kunna uppnå en nästintill maximal flexibilitet respektive effektivitet i lärandet.

The single-aliquot regenerative-dose (SAR) protocols used in retrospective dosimetry for optically stimulated luminescence measurements have been mainly developed for archaeological and geological dating of quartz and feldspar. The aim in this study is to find a read-out protocol that can generate the most reproducible signal for household salt (NaCl) at absorbed doses below 100 mGy. The relation

Microdosing is a new concept in drug development that-if implemented in the pharmaceutical industry-would mean that new drugs can be tested earlier in humans than done today. The human microdosing concept-or 'Phase 0'-may offer improved candidate selection, reduced failure rates in the drug development line and a reduction in the use of laboratory animals in early drug development, factors which w

Aims In a cohort of men and women with Type 1 diabetes, prospectively followed for > 20 years, vibrotactile sense in fingers was investigated and related to neurophysiological tests, glycaemic level and clinical score. Methods Out of 58 patients, diagnosed at the age of 15-25 years and recruited 1984-1985, 32 patients (13 women, median age 52 years, range 44-75 years; 19 men, median age 52 years,