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Chronic obstructive pulmonary disease (COPD) is a leading cause of death world-wide. Recently, we showed that COPD is associated with gene polymorphisms in SUMF1, a master regulator of sulfatases. Sulfatases are involved in extracellular matrix remodeling and activated by SUMF1, but their role in the lung is poorly described. We aimed to examine how sulfatases are affected in the airways of patien

Existing knowledge suggests that people's willingness to pay (WTP) for climate change mitigation depends not only on personal characteristics but also on the payment vehicle (PV) that is used to elicit WTP. The aim of this research is to investigate policy-relevant differences in WTP between different PVs to support the design of carbon pricing mechanisms. The novelty of this contingent valuation

Climate change has been shown to shift the seasonal timing (i.e. phenology) and distribution of species. The phenological effects of climate change on living organisms have often been tested using first occurrence dates, which may be uninformative and biased. More rarely investigated is how different phases of a phenological sequence (e.g. beginning, central tendency and end) or its duration have

The inclusive production of four isolated charged leptons in pp collisions is analysed for the presence of hard double-parton scattering, using 20.2 fb −1 of data recorded in the ATLAS detector at the LHC at centre-of-mass energy s=8 TeV. In the four-lepton invariant-mass range of 80

We attempt to integrate the literatures on authoritarian regime types and democratic forms of government. We propose a theoretical framework of five dimensions of executive appointment and dismissal that can be applied in both more democratic and more authoritarian regimes: the hereditary, military, ruling party, direct election, and confidence dimensions, respectively. Relying on the Varieties of

Background: Uncomplicated urinary tract infection (uUTI) is common and a majority of patients are prescribed antibiotics. There is little knowledge about antibiotic resistance in urine samples from patients with uUTI in primary health care (PHC). The aim was to describe antibiotic treatment, bacterial findings, the prevalence of resistant E.coli and factors associated with antibiotic resistance. T

Background: The survival rate for dialysis patients is poor. Previous studies have shown improved survival with home hemodialysis (HHD), but this could be due to patient selection, since HHD patients tend to be younger and healthier. The aim of the present study is to analyse the long-term effects of HHD on patient survival and on subsequent renal transplantation, compared with institutional hemod

Background: Patients with unprovoked first venous thromboembolism (VTE) are at a high risk of recurrence. Although circulating microRNAs (miRNAs) have been found to be associated with VTE and are markers of hypercoagulability, this study is the first to examine whether circulating miRNAs are associated with the risk of VTE recurrence. Results: A nested case-control study design was used where plas

Artikeln handlar om felparkeringsrätt - klarlägger rättsläget och undersöker konflikten mellan krav på effektiva rättsregler å ena sidan och krav på rättssäkerhet å andra sidan

We report x-ray free electron laser experiments addressing ground-state structural dynamics of the diplatinum anion Pt2POP4 following photoexcitation. The structural dynamics are tracked with <100 fs time resolution by x-ray scattering, utilizing the anisotropic component to suppress contributions from the bulk solvent. The x-ray data exhibit a strong oscillatory component with period 0.28 ps and

UN Sustainable Development Goal (SDG) 7 states that access to affordable, reliable, sustainable, and modern energy should be provided for all by 2030. Mozambique is one of the poorest countries on earth but has abundant supply of energy resources. The electrification rate, however, has been slow. Rural electrification is hampered by lack of basic infrastructure, institutional barriers, and low abi

BACKGROUND: Systemic sclerosis (SSc) has been suggested to cause exocrine pancreatic dysfunction. However, a case-control-based autopsy study failed to associate systemic sclerosis with any pancreatic histopathology. The primary objective of this study was to examine the exocrine pancreatic function in consecutive SSc patients in relation to an age- and sex-matched control group. A secondary objec

BACKGROUND: Musculoskeletal (MSK) disorders are less likely to be reported as an underlying cause of death (UCD) and since cause of death studies are generally limited to the UCD, little is known about socioeconomic inequalities in MSK disorders as cause of death in the general population. Using multiple-cause-of-death data, we aimed to quantify and compare educational inequalities in musculoskele

Femtosecond laser-induced plasma spectroscopy for in situ ammonia (NH 3 ) measurements was demonstrated in NH 3 ∕N 2 mixtures. When a femtosecond laser at 800 nm was focused at the flow field, the parent NH 3 molecules would be photolyzed to generate electronics excited NH fragments, and then indirect measurements of NH 3 could be realized by detecting the NH fluorescence (A 3 Π − X 3 Σ −

We present measurements of elliptic and triangular azimuthal anisotropy of charged particles detected at forward rapidity 1

Background: In anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis, antigen specificity varies between myeloperoxidase (MPO) and proteinase 3 (PR3). This has been reported to vary in relation to age, gender, geography and extrarenal manifestations. However, studies are difficult to compare as criteria for inclusion vary. The aim of this study was to investigate the relationsh

Background: Lean body mass (LM) plays an important role in mobility and metabolic function. We previously identified five loci associated with LM adjusted for fat mass in kilograms. Such an adjustment may reduce the power to identify genetic signals having an association with both lean mass and fat mass. Objectives: To determine the impact of different fat mass adjustments on genetic architecture

The response of the ATLAS detector to large-radius jets is measured in situ using 36.2 fb - 1 of s=13 TeV proton–proton collisions provided by the LHC and recorded by the ATLAS experiment during 2015 and 2016. The jet energy scale is measured in events where the jet recoils against a reference object, which can be either a calibrated photon, a reconstructed Z boson, or a system of well-measured sm

It is unknown whether the risk factor profile for mesenteric venous thrombosis (MVT) is different from systemic venous thromboembolism (VTE). The aim of the present population-based study was to compare acquired and inherited risk factors in MVT versus VTE. Identification of all MVT patients at Skåne University Hospital between 2000 and 2015 was performed in patient records and AuriculA (Swedish a