Background: The Parkinson Disease (PD) Home Diary (HD) is a commonly used clinical outcome measure, but it has not been extensively compared to direct assessments by experienced observers.Objective: Validation of patient-reported HD by investigating the agreement between motor state assessments by patients and observers.Methods: This observational study included patients with PD and motor fluctuat

Strength interventions at work have been shown to influence workers’ optimal functioning and well-being. To increase the accessibility of these interventions in the workplace, relying on digital platforms would be a realistic idea. Akin to the Character Strengths 360-degree feedback activity, a smartphone (and computer) application allows users to send or receive anonymous strength-oriented descri

In this study, we present summertime concentrations and fluxes of biogenic volatile organic compounds (BVOCs) measured at a sub-arctic wetland in northern Sweden using a disjunct eddy-covariance (DEC) technique based on a proton transfer reaction mass spectrometer (PTR-MS). The vegetation at the site was dominated by Sphagnum, Carex and Eriophorum spp. The performance of the DEC system was assesse

Meteorological investigations were carried out in forests in the southwestern part of the Swabian Alb (SW Germany) to analyze the influences of exposition and silvicultural treatment on the microchmate within various stands of beech (Fagus sylvatica L.). The measurements were taken as part of an interdisciplinary project on the effects of climate and forest management on structures and processes w

Oil-in-water emulsions have been stabilized by functionalized cellulose nanofibrils bearing either a negative (oxidized cellulose nanofibrils, OCNF) or a positive (cationic cellulose nanofibrils, CCNF) surface charge. The size of the droplets was measured by laser diffraction, while the structure of the shell of the Pickering emulsion droplets was probed using small-angle neutron scattering (SANS)

Maternal smoking during pregnancy constitutes a potential, major risk factor for adult male reproductive function. In the hitherto largest longitudinal cohort, we examined biomarkers of reproductive function according to maternal smoking during the first trimester and investigated whether associations were mitigated by smoking cessation prior to the fetal masculinization programming window. Associ

This paper presents the first Lateglacial/Holocene (the last 13 500 cal a bp) ostracod δ18O record to infer hydroclimate variability in the Southern French Alps. Cytherissa lacustris (δ18Osp) shells extracted from the sediments of Lake Allos allowed a reconstruction of δ18Olake water (δ18Olw) except for the interval 5800–2800 cal a bp. The shape of the Younger Dryas (YD) clearly differed from reco

Aquaporin channels facilitate bidirectional water flow in all cells and tissues. AQP4 is highly expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at the glia limitans, where it mediates water exchange across the blood-spinal cord and blood-brain barriers (BSCB/BBB), and controls cell volume, extracellular space volume, and astrocyte migration. Perivascular

The chapter focuses on the religious aspects of India’s international relations by paying attention to four interrelated developments, discourses and narratives. First is the more general understanding of the role of religion in the Indian national narrative after independence, outlining how India’s policy of non-alignment and exceptionalism served as a site for a particular representation of Indi

Attosecond pulses in the extreme ultraviolet (XUV) spectral range are today routinely generated via high-order harmonic generation (HHG), when intense ultrashort laser pulses are focused into a gaseous generation medium. The effect is most easily understood in a semi-classical picture [1]. An electron can tunnel ionize from the distorted atomic potential, pick up kinetic energy in the laser field,

This article focuses on young unemployed in Sweden involved in two activation measures. Using the analytical framework of governmentality, it analyses how the participants perceive and value activation measures as government-driven intervention aimed at bringing young people into the labour market, based on a neoliberal discourse in the welfare state. The article highlights that the welfare system

Nanowires have many interesting properties that are of advantage for solar cells, such as the epitaxial combination of lattice-mismatched materials without plastic deformation. This could be utilized for the synthesis of axial tandem-junction nanowire solar cells with high efficiency at low material cost. Electron-beam-induced current measurements have been used to optimize the performance of sing

Despite improvements, lung transplantation remains hampered by both a scarcity of donor organs and by mortality following primary graft dysfunction (PGD). Since acute respiratory distress syndrome (ARDS) limits donor lungs utilization, we investigated cytokine adsorption as a means of treating ARDS donor lungs. We induced mild to moderate ARDS using lipopolysaccharide in 16 donor pigs. Lungs were

Background: Growth differentiation factor 15 (GDF-15) has been associated with the risk of developing major bleedings, including but not restricted to intracranial hemorrhages, in patients on oral anticoagulants or dual antiplatelet therapy. We hypothesized that there may be an association of GDF-15 with incidence of hemorrhagic strokes in the general population, which has not been investigated be

Review of Anna-Maija Multas PhD thesis from 2022: New health information literacies. A nexus analytical study. Acta universitatis OuluensisB Humaniora 192, University of Oulu, Oulu

Human in vitro models of neural tissue with tunable microenvironment and defined spatial arrangement are needed to facilitate studies of brain development and disease. Towards this end, embedded printing inside granular gels holds great promise as it allows precise patterning of extremely soft tissue constructs. However, granular printing support formulations are restricted to only a handful of ma

Background: Delayed cerebral ischemia (DCI), a complication of subarachnoid hemorrhage (SAH), is linked to cerebral vasospasm and associated with poor long-term outcome. We implemented a structured cerebral microdialysis (CMD) based protocol using the lactate/pyruvate ratio (LPR) as an indicator of the cerebral energy metabolic status in the neurocritical care decision making, using an LPR ≥ 30 as