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INSIDE : An efficient guide for sustainable remediation practice in addressing contaminated soil and groundwater

Modeling criteria interaction in decision-making problems is complex and often neglected. In complicated problems, like contaminated site remediation projects, independency of involved criteria is not a realistic assumption. INfluence based deciSIon guiDE (INSIDE) is a methodology that enables sustainable decision making and management in contaminated site remediation practice. Unlike most previou

A Scheimpflug lidar used to observe insect swarming at a wind turbine

Wind turbines have considerable impact on flying animals, particularly bats, which are sometimes killed in large numbers by the moving rotors. A longstanding question remains why bats are attracted to wind turbines and risk their lives among the moving rotor blades. One hypothesis is that they feed on insects swarming around the turbine towers and another is that they congregate there to court. Th

Structure and propagation of n-heptane/air premixed flame in low temperature ignition regime

This paper presents a large eddy simulation of n-heptane/air turbulent premixed combustion in a reactor assisted turbulent slot (RATS) burner under different preheating conditions. N-heptane/air mixture at an equivalence ratio of 0.6, pressure of 1 atm and temperature of 600, 650 and 700 K is considered to investigate the effect of low temperature chemistry on turbulent burning velocities and flam

An investigation of the enzymatic cleavage of κ-casein in non-coagulating milk

Non-coagulating milk is unwanted in cheese production because it impairs chymosin-induced coagulation properties in bulk milk. Milk samples were analysed to investigate the coagulation process in non-coagulating milk for comparison with milk samples that have a high coagulation ability. This was done by measuring two peptides after chymosin cleavage, namely para-κ-casein and caseinomacropeptide, i

Influence of alternating V-rows tube layout on thermal-hydraulic characteristics of twisted elliptical tube heat exchangers

An innovative alternating V-rows triangular tube layout was devised for the twisted elliptical tube heat exchangers to enhance heat transfer between adjacent tubes. Under the same tube circumference, altogether eleven twisted elliptical tube heat exchangers with two tube layouts, diverse aspect ratios of twisted elliptical tubes and different twisted pitches were constructed and simulated, includi

Enabling new mindsets and transformative skills for negotiating and activating climate action : Lessons from UNFCCC conferences of the parties

Technological and policy solutions for transitioning to a fossil-free society exist, many countries could afford the transition, and rational arguments for rapid climate action abound. Yet effective action is still lacking. Dominant policy approaches have failed to generate action at anywhere near the rate, scale or depth needed to avoid potentially catastrophic futures. This is despite 30 years o

Application of extreme gradient boosting and parallel random forest algorithms for assessing groundwater spring potential using DEM-derived factors

Groundwater (GW) resources provide a large share of the world's water demand for various sections such as agriculture, industry, and drinking water. Particularly in the arid and semi-arid regions, with surface water scarcity and high evaporation, GW is a valuable commodity. Yet, GW data are often incomplete or nonexistent. Therefore, it is a challenge to achieve a GW potential assessment. In this

ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma

The master regulator of neuroendocrine differentiation, achaete-scute complex homolog 1 (ASCL1) defines a subgroup of lung adenocarcinoma. However, the mechanistic role of ASCL1 in lung tumorigenesis and its relation to the immune microenvironment is principally unknown. Here, the immune landscape of ASCL1-positive lung adenocarcinomas was characterized by immunohistochemistry. Furthermore, ASCL1

Electron channelling : challenges and opportunities for compositional analysis of nanowires by TEM

Energy dispersive x-ray spectroscopy in a transmission electron microscope is often the first method employed to characterize the composition of nanowires. Ideally, it should be accurate and sensitive down to fractions of an atomic percent, and quantification results are often reported as such. However, one can often get substantial errors in accuracy even though the precision is high: for nanowir

Imbalance of the oxytocin-vasopressin system contributes to the neuropsychiatric phenotype in the BACHD mouse model of Huntington disease

Neuropsychiatric disturbances with altered social cognition, depression and anxiety are among the most debilitating early features in the fatal neurodegenerative disorder Huntington disease (HD) which is caused by an expanded CAG repeat in the huntingtin gene. The underlying neurobiological mechanisms are not known. Neuropathological analyses of postmortem human HD hypothalamic tissue have demonst

Story-dismantling, story-meandering, and story-confirming : Organizational identity work in times of public disgrace

This study aims to enhance our understanding of organizational identity work (OIW), building upon previous studies’ emphasis on the usefulness of understanding OIW in terms of storytelling. The paper offers an extended vocabulary for making sense of alternative narration forms. Based on an in-depth study of a humanitarian organization in Sweden, the discursive OIW struggles of employees in times o

Severe retinitis pigmentosa phenotype associated with novel CNGB1 variants

Purpose: To report a severe phenotype of retinitis pigmentosa associated with novel mutations in CNGB1. Observations: Six siblings, age range 50–75 years old, were examined using optical coherence tomography and fundus autofluorescene, electroretinogram testing, Goldman visual field testing, and genetic testing using next generation sequencing. In four affected siblings, two novel compound heteroz

Polymorphism in killer cell immunoglobulin-like receptors and human leukocyte antigen-c and predisposition to preeclampsia in Ethiopian pregnant women population

Introduction: Preeclampsia (PE) is a human specific pregnancy-related syndrome of unknown etiology that affects 2–8 % of pregnancies. Polymorphism in maternal Killer Cell Immunoglobulin-like Receptors (KIRs) and the ligand fetal Human Leukocyte Antigen-C (HLA-C) may predispose pregnant mothers for PE due to defective trophoblast invasion into the maternal decidua. Our study aimed to investigate th

Disentangling drivers of soil microbial potential enzyme activity across rain regimes : An approach based on the functional trait framework

The functional trait framework provides a powerful corpus of integrated concepts and theories to assess how environmental factors influence ecosystem functioning through community assembly. While common in plant ecology, this approach is under-used in microbial ecology. After an introduction of this framework in the context of microbial ecology and enzymology, we propose an approach 1) to elucidat

Endogenous regime change : Lessons from transition pathways in Dutch dairy farming

Sustainability transitions are commonly considered impossible without regime change. Theoretical work on regime change has mainly focused on niches and landscapes and less on change ‘from within’. Empirical analysis helps theorising endogenous regime change. Conceptualising regimes as semi-coherent entities composed of multiple ‘institutional logics’, we analyse the endogenous regime change in Dut

A method to estimate absence in apartments based on domestic water use

Today, every new building is constructed with the ambition of it having a very low energy demand or even being completely neutral with regard to supply and demand over a year. In modern low energy or nearly zero energy residential buildings like these, the behaviour of the occupants becomes increasingly more significant in terms of the energy performance of the building. Occupants who are present

Excess Morbidity Persists in Patients With Cushing's Disease During Long-term Remission : A Swedish Nationwide Study

CONTEXT: Whether multisystem morbidity in Cushing's disease (CD) remains elevated during long-term remission is still undetermined. OBJECTIVE: To investigate comorbidities in patients with CD. DESIGN, SETTING, AND PATIENTS: A retrospective, nationwide study of patients with CD identified in the Swedish National Patient Register between 1987 and 2013. Individual medical records were reviewed to ver

Propensity rules and interference effects in laser-Assisted photoionization of helium and neon

We investigate the angle-resolved photoelectron spectra from laser-Assisted photoionization for helium and neon atoms using an ab initio method based on time-dependent surface flux and configuration interaction singles. We find that the shape of the distributions can be interpreted using a propensity rule, an intrinsic difference in the absorption and the emission processes, as well as interferenc

Study of the possibilities with combinations of circularly and linearly polarized light for attosecond delay investigations

We present calculations on the atomic delay in photoionzation obtained with different combinations of linearly and circularly polarized light, and show how a tensor operator approach can be used to readily obtain results for any combination from a single calculation of the radial integrals. We find that for certain choices of polarization and detection geometry a single time-delay measurement is e