Cigarette smoke is the most relevant risk factor for the development of lung cancer and chronic obstructive pulmonary disease. Many of its more than 4500 chemicals are highly reactive, thereby altering protein structure and function. Here, we used subcellular fractionation coupled to label-free quantitative MS to globally assess alterations in the proteome of different compartments of lung epithel

The chemical composition of calcium phosphate (CaP) materials for the regenerative therapy of large bone defects is similar to that of bone. Additionally, calcium phosphates show an excellent biocompatibility. Besides the support of defect healing calcium phosphate implants should be completely degraded within an adequate time period to be replaced by newly formed bone. Although degradation of CaP

Chronic lung diseases such as asthma, chronic obstructive pulmonary disease (COPD), and idiopathic pulmonary fibrosis (IPF) are all characterized by structural changes of the airways and/or lungs that limit airflow and/or gas exchange. Currently, there is no therapy available that adequately targets the structural remodeling of the airways and lungs in these diseases. This underscores the great ne

Hydroxyapatite (HA) ceramic is a widely used synthetic bone substitute material for the regeneration of bone defects. We manufactured HA scaffolds with adjustable pore sizes and pore geometry by dispense-plotting. In addition, we attached peptides covalently onto the HA surface and are able to simultaneously quantify the amount of covalently attached and adsorbed peptide down to the picomolar rang

Medical doctors and nutritional specialists recommend to eat healthy foods including fruits and vegetables. Cosmetic experts also recommend to use cosmetic products obtained from natural products. The reason behind this is that natural products from plants contain chemical compounds which can promote health and protect our bodies from several diseases. These chemical compounds are called bioactiveBioactive compounds found in plants have been of interest to man since ancient times. These compounds have the ability to modulate the metabolic processes in our bodies, which suggests that they may promote better health. Bioactive compounds vary in their chemical structure, polarity, stability and biological activity. This diversity makes the study of bioactive compounds challenging from the pers

According to the International Energy Agency about 14% of greenhouse gases (GHG) are generated by the transportation sector globally and this share is estimated to increase to 50% by 2030. At the same time consumption of mobility is continuously increasing, making it one of the most crucial sectors to focus on for sustainable consumption. Several measures and policies are being implemented to redu

It is increasingly apparent that technology and online platforms entail and communicate normativity. Lawrence Lessig has described this in terms of 'code as law' and thereby pointing to the fact that there is an ongoing shift of power from nation states to tech companies, and José van Dijck has shown how the Big Five - Google (Alphabet), Apple, Amazon, Facebook, Microsoft - represents a neo-liberaIt is increasingly apparent that technology and online platforms entail and communicate normativity. Lawrence Lessig has described this in terms of 'code as law' and thereby pointing to the fact that there is an ongoing shift of power from nation states to tech companies, and José van Dijck has shown how the Big Five - Google (Alphabet), Apple, Amazon, Facebook, Microsoft - represents a neo-libera

We point out the risks of protecting relational databases via Searchable Symmetric Encryption (SSE) schemes by proposing an inference attack exploiting the structural properties of relational databases. We show that record-injection attacks mounted on relational databases have worse consequences than their file-injection counterparts on un- structured databases. Moreover, we discuss some technique

Gemmell and Naor proposed a new protocol for the authentication of long messages which was based on block codes and which used a transmission channel k times. This multiround authentication makes it possible to limit the key size independently of the message length. We propose a new attack and show that the probability analysis made by Gemmell and Naor, which was only based on the minimum distance

The internationalization of firms has led to boards becoming more international as well. In this study, we investigate the consequences of board internationalization. In particular, by drawing on research on language and board dynamics, we identify theory-based reasons why board internationalization could increase, or decrease, earnings management practices. We use agency theory, stressing how boa

Many neurological diseases are followed by a disturbance of nutritional intake to some extent and thus constitute the most common indication for nutritional support and enteral access. Several studies have shown that malnutrition is a common condition, with as many as 40% of admitted patients being identified as undernourished and 78% of these further found to be deteriorated in their nutritional

Functional gastrointestinal disorders constitute a set of gastrointestinal disorders with absence of obvious organic and physiological dysfunctions observed in clinical routine examinations. The functional disorders are divided into many subclasses, e.g., functional esophageal disorders and functional bowel disorders. The diagnoses are set when the patients fulfil the Rome IV criteria after a care

Dansmästarna vid Lund universitet 1668-1855. Excertitier för adelns behov.

Dysphagia with a psychiatric background is a rare condition, not so well understood, and presented with no structural or organic disease detectable. More research would therefore be of importance for more knowledge about this condition that in several cases affects the quality of life in a negative way. Fear of swallowing, avoidance of swallowing specific foods, fluids, or pills seem to be the mos

Radiologic examination of the oral cavity, pharynx, and esophagus should focus on bolus transportation as well as on registration of morphodynamic events. The examination should be custom-tailored to the patient’s symptoms but should also be performed in a rather standardized way. The radiologic findings should always be compared to the patient’s specific symptoms.

Kvinnliga historiestudenter vid Lunds universitet 1904-1913.

Research evaluation practices linked to social impact have important systemic effects on the prioritization and organization of research while at the same time leading to the delivery of higher social value. Amidst growing criticisms, global research evaluation has evolved in a different direction, characterized by quantitative metrics and mimetic behavior. The article deals with the forces that sResearch evaluation practices linked to social impact have important systemic effects on the prioritization and organization of research while at the same time leading to the delivery of higher social value. Amidst growing criticisms, global research evaluation has evolved in a different direction, characterized by quantitative metrics and mimetic behavior. The article deals with the forces that s