The characterization of structure over a wide range of length scales from atomic to microns is a common requirement for understanding the behaviour of many soft matter systems. In the case of self-assembling and colloidal materials, the final properties will depend sensitively on intermolecular as well as interparticle interactions. Experimental methods such as wide and small angle scattering, whi

We currently use Convection-Enhanced Delivery (CED) of the platinum-based drug, carboplatin as a novel treatment strategy for high grade glioblastoma in adults and children. Although initial results show promise, carboplatin is not specifically toxic to tumour cells and has been associated with neurotoxicity at high infused concentrations in pre-clinical studies. Our treatment strategy requires in

In the past few years there has been a growth in the use of nanoparticles for stabilizing lipid membranes that contain embedded proteins. These bionanoparticles provide a solution to the challenging problem of membrane protein isolation by maintaining a lipid bilayer essential to protein integrity and activity. We have previously described the use of an amphipathic polymer (poly(styrene-co-maleic

PLGA/PLA polymeric nanoparticles could potentially enhance the effectiveness of convective delivery of drugs, such as carboplatin, to the brain, by enabling a more sustained dosage over a longer time than otherwise possible. However, the link between the controlled release nanoparticle synthesis route, and the subsequent drug release profile obtained, is not well-understood, which hinders design o

In Europe, individualist societies, in which people more highly value independence, have fewer people who are lonely. Yet these societies also have more people who live alone, a strong determinant of loneliness. Evidence suggests that some unrecognized societal-level resources or characteristics can explain this.We uncover multiple pathways toward a lower degree of loneliness among European societ

Orthoptera are infected by about 60 species of gregarines assigned to the genus Gregarina Dufour, 1828. Among these species, Gregarina garnhami Canning, 1956 from Schistocerca gregaria (Forsskål, 1775) was considered by Lipa et al. in 1996 to be synonymous with Gregarina acridiorum (Léger 1893), a parasite of several orthopteran species including Locusta migratoria (Linné, 1758). Here, a morpholog

AimA person's ability to tolerate negative emotional states (Distress Tolerance - DT), uncertainty in their everyday lives (Intolerance of Uncertainty - IU), and a tendency to appraise their own feelings of anxiety as harmful (Anxiety Sensitivity - AS) have all been identified as vulnerability factors for anxiety and depressive disorders. However, the relationship between these variables and broad

INTRODUCTION: Immune cells in the tumour microenvironment are associated with prognosis and response to therapy. We aimed to comprehensively characterise the spatial immune phenotypes in the mutational and clinicopathological background of non-small cell lung cancer (NSCLC).METHODS: We established a multiplexed fluorescence imaging pipeline to spatially quantify 13 immune cell subsets in 359 NSCLC

We develop a deep learning model that uses financial news articles and historical exchange rates to predict the rate for the Euro/US Dollar currency pair one hour ahead. From the articles’ titles and bodies we extract sentiment scores using two different transformer based classifiers – one for short text and one for long text. The long-text classifier is built and trained by us. These sentiment sc

The electronic structure of C60n- molecules and ions and C60Kn (n=0-4,6) crystals is investigated in the zero diatomic overlap approximation. The calculated characteristics of the carbon-carbon chemical bond in fullerenes and fullerites are compared with the bond characteristics in simpler covalent carbon-containing compounds, viz.: selected hydrocarbons, graphite, and diamond. It is shown that t

Recension (understreckare) om Mikael Holmqvist, "Kungen: Sveriges ledare"

In this study, we discuss Swedish travelers from different backgrounds during their visits to Greece and Asia Minor in the 18th century. Besides their scientific interests, they write about their impressions of the Greeks and other people in the area, as well as education, language, religion, local economy, culture, and social life. They have good knowledge of ancient Greek history and the Greek l

This work investigates the black hole (BH) population of globular clusters (GCs) in Milky Way- and Andromeda-like galaxies. We combine the population synthesis code MASinGa and the MOCCA-Survey Database I to infer the properties of GCs harbouring a stellar-mass BH subsystem (BHS), an intermediate-mass BH (IMBH), or neither of those. We find that the typical number of GCs with a BHS, an IMBH, or

The Laser Interferometer Space Antenna (LISA) will be a transformative experiment for gravitational wave astronomy, and, as such, it will offer unique opportunities to address many key astrophysical questions in a completely novel way. The synergy with ground-based and space-born instruments in the electromagnetic domain, by enabling multi-messenger observations, will add further to the discov

Free-standing titania films were grown at the air-water interface, a novel method to synthesize robust TiO2 nanowire/nanoparticle composite films. The calcined films contain an anatase crystal phase and have a high surface area with a structure composed of one-dimensional long nanowires and mesoporous nanoparticle branches. These suggest a promising way to manufacture large areas of thick porous t

Whereas theoretical attacks on standardized crypto primitives rarely lead to actual practical attacks, the situation is different for side-channel attacks. Improvements in the performance of side-channel attacks are of utmost importance.In this paper, we propose a framework to be used in key-recovery side-channel attacks on CCA-secure post-quantum encryption schemes. The basic idea is to construct

Study of phonon and electron subsystems of C60I4-x and C60Br24 crystals has shown a different character of chemical bonding in these materials: C60I4-x is a compound with weak van der Waals interaction between C-60 and I-2 molecules whereas C60Br24 is a covalent crystal with a charge transfer between nearest C and Br atoms.