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The mechanisms by which mycobacteria subvert the inflammatory defence to establish chronic infection remain an unresolved question in the pathogenesis of tuberculosis. Using primary epithelial cells, we have analysed mycobacteria induced epithelial signalling pathways from activation of TLRs to cytokine secretion. Mycobacterium bovis bacilli Calmette-Guerin induced phosphorylation of glycogen synt

Prey organisms often use multiple sensory cues to gain reliable information about imminent predation threat. In this study we test if a freshwater fish increases the reliance on supplementary cues when the reliability of the primary cue is reduced. Fish commonly use vision to evaluate predation threat, but may also use chemical cues from predators or injured conspecifics. Environmental changes, su

PURPOSE: To explore areas in which the education at the Pakistan Institute of Prosthetic & Orthotic Science (PIPOS) could be improved or supplemented to facilitate clinical practice of graduates. To describe educational opportunities PIPOS graduates have had since their graduation and explore their further educational needs. METHOD: 15 graduates from PIPOS participated in semi-structured inte

Abstract is not available

Perhaps the time has come to relativise relativism? That is the aim of the present article. Although many take a strong position against relativism, relativising and deconstructive traits are important and indispensable in scientific and intellectual work. The aspect of relativising, putting into perspective, or saying that things are dependent on background, is generally emphasised in description

En artikel om hur slaget vid Gettysburg har varit omstritt från 1863 fram tills 150-årsminnet 2013.

Neisseria meningitidis serogroup B (MnB) is a leading cause of invasive meningococcal disease in adolescents and young adults. A recombinant factor H binding protein (fHBP) vaccine (Trumenba(®); bivalent rLP2086) was recently approved in the United States in individuals aged 10-25 years. Immunogenicity and safety of 2- or 3-dose schedules of bivalent rLP2086 were assessed in adolescents.

The position of English vis-à-vis Swedish in Sweden is gaining attention because of a growing concern that the encroachment of English in certain domains may result in Swedish losing ground. A current language policy proposal, entitled Mål i mun, commissioned by the Swedish government addresses this concern, in part, by outlining recommendations for the respective roles of Swedish and English (a)

Abstract is not available