Glyoxalase I (GlxI) is an important enzyme that catalyzes the detoxification of methylglyoxal (MG) with the help of glutathione (H-SG). It is currently unclear whether MG and H-SG are substrates of GlxI or whether the enzyme processes hemithioacetal (HTA), which is nonenzymatically formed from MG and H-SG. Most previous studies have concentrated on the latter mechanism. Here, we study the two-subs

Due to its high hole-mobility, GaSb is a highly promising candidate for high-speed p-channels in electronic devices. However, GaSb exhibits a comparably thick native oxide causing detrimental interface defects, which has been proven difficult to remove. Here we present full oxide removal from GaSb surfaces using effective hydrogen plasma cleaning, studied in-situ by synchrotron-based X-ray photoel

Recent clinical trials of mesenchymal stromal cell (MSC) therapy for various inflammatory conditions have highlighted the significant benefit to patients who respond to MSC administration. Thus, there is strong interest in investigating MSC therapy in acute inflammatory lung conditions, such as acute respiratory distress syndrome (ARDS). Unfortunately, not all patients respond, and evidence now su

Background: Middle Eastern immigrants represent a growing population in Sweden today. This group are at higher risk for type 2 diabetes than the native population, but are also shown to exhibit unique properties; despite an abundance in traditional cardiometabolic risk factors such as obesity, dearranged blood lipids and diminished physical acitivity, this group seem to exhibit lower blood pressur

While there is almost unanimous consent among scientists that climate change is real and has detrimental consequences, there is a sizable number of people who are skeptical towards these propositions and who are not worried by climate change. In an attempt to understand the basis of climate skepticism, we look at the role of intolerance, a culturally transmitted attitude to the effect that people

Detailed reaction kinetics of acrolein + H and related chemistry and its influence on the ignition delay time prediction of acrolein has been studied theoretically in this work. The geometry optimization and vibrational frequency calculations for every stationary point were performed at the BH&HLYP/6–311++G(d,p) level of theory, with one-dimensional hindered rotation treatments applied for low

The learning with errors (LWE) problem is one of the main mathematical foundations of post-quantum cryptography. One of the main groups of algorithms for solving LWE is the Blum–Kalai–Wasserman (BKW) algorithm. This paper presents new improvements of BKW-style algorithms for solving LWE instances. We target minimum concrete complexity, and we introduce a new reduction step where we partially reduc

Alternative food networks (AFNs) have the potential to enhance and redistribute value in favour of producers and consumers through novel ways of organizing supply chain activities. What is more, AFNs are often characterized by their ‘sustainability promise’ – or the idea that their networks foster social, ecological or environmental improvements over conventional food networks. Based on a purposiv

In solids, strong repulsion between electrons can inhibit their movement and result in a “Mott” metal-to-insulator transition (MIT), a fundamental phenomenon whose understanding has remained a challenge for over 50 years. A key issue is how the wave-like itinerant electrons change into a localized-like state due to increased interactions. However, observing the MIT in terms of the energy- and mome

Ferdinand Tönnies sociologi är en ursociologi – för att inte säga själva ursociologin. Hans sociologi börjar och slutar med begreppen Gemeinschaft och Gesellschaft, ungefär gemenskap och samhälle. Det är begrepp som allt sedan den tidiga sociologin varit grundläggande för disciplinens utveckling. Det är också begrepp som är djupt rotade i erfarenheten av att vara en modern människa, erfarenheten a

Abstract Background: The Acceptance and Action Questionnaire-Trauma Specific (AAQ-TS) is a self-report measure designed to assess-trauma-related psychological (in)flexibility, as conceptualized in Acceptance and Commitment Therapy. However, there are no studies to date regarding its psychometric properties. This study explores such properties in the Portuguese version of the AAQ-TS, in Portuguese

Human papillomavirus (HPV) is the main causal agent of tonsillar cancer (TC) and HPV+ TC has a favorable prognosis compared to HPV– disease. In this study, we examined aspects of the tumor microenvironment of TC, focusing on T‐cells, dendritic cells (DC), and macrophages. Fresh biopsies of TC and the contralateral healthy tonsil (HT) were obtained from 20 patients, analyzed by multiparameter flow

Background: Stroke is a common cause of mortality and disability worldwide and continuously updated, thorough information of itsoccurrence and outcome is needed. In recent years, multiple advances have been made in stroke prevention and treatment that mayhave changed the epidemiology and outcome of stroke.Aims: To investigate updated population-based stroke epidemiology as well as long-term surviv

Recent interest in applying novel imaging techniques to infer optical resolution in compound eyes underscores the difficulty of obtaining direct measures of acuity. A widely used technique exploits the principal pseudopupil, a dark spot on the eye surface representing the ommatidial gaze direction and the number of detector units (ommatidia) viewing that gaze direction. However, dark-pigmented eye

Recension av Carl Henrik Carlsson, Judarnas historia i Sverige.