The complement system has vital protective functions as a humoral component of the innate immune system and also through interactions with the adaptive immune system; however, when inappropriately activated or regulated, complement can cause inflammation and organ damage, and such processes are involved in the pathogenesis of many inflammatory conditions, not least rheumatic diseases. Furthermore,

BACKGROUND: Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas. RESUL

BACKGROUND: Type 2 diabetes mellitus is thought to develop from an interaction between environmental and genetic factors. We examined whether clinical or genetic factors or both could predict progression to diabetes in two prospective cohorts. METHODS: We genotyped 16 single-nucleotide polymorphisms (SNPs) and examined clinical factors in 16,061 Swedish and 2770 Finnish subjects. Type 2 diabetes d

In this paper, an F'F'GA implementation of a novel and highly scalable hardware architecture for fast inversion of triangular matrices is presented. An integral part of modem signal processing and communications applications involves manipulation of large matrices. Therefore, scalable and flexible hardware architectures are increasingly sought for. In this paper, the traditional triangular shaped

In this paper we consider control signal properties, such as maximum magnitude and activity, as well as system robustness measures. We derive an ideal controller and control signal for exponential disturbance rejection for a first order process with time delay. For the resulting closed-loop system, it is shown analytically that there are strong interconnections between robustness measures and cont

The paper contains an experimental validation of the physically based brush-tire model toward the tire behavior in a number of different realistic conditions. Results of measurements performed with summer, winter, and studded tires on different road foundations such as wet and dry asphalt, basalt, snow, and ice are presented. The purpose behind the validation is to study the possibilities of using

Abstract in UndeterminedTo study the phenomenology of hypnotic virtuosos, theauthor employed a 2 (hypnosis vs. control) × 3 (quiescent, pedaling astationary bike, having a motor pedal the bike) within-subjects designwith quantitative and qualitative measures. In a “neutral hypnosis”context with the only suggestion being to go as deeply into hypnosisas possible, participants reported alterations in

In parallel with the changes observed in the world of work, the scope of occupational health and safety should be understood in a way that encompasses psychosocial risks. This necessity stems from the principle that occupational health and safety should be dealt with through a dynamic approach and finds itself a place in the national and international legal order. The scope of this thesis in terms

When exactly does an eviction occur according to the Strasbourg Court? In Jansons v Latvia (application no. 1434/14), this question lurks behind the majority’s reasoning and the dissenting opinion of Judge O’Leary. This case is one of the “verticalized” cases brought before the Court, concerning, in essence, a private law dispute between the individual applicant and a private company in the contex

This article explores how the right to respect one’s home under Article 8 of the European Convention on Human Rights would apply in the context of housing and social control. After explaining the connections between social control, housing, and human rights, it analyzes the selected case law of the European Court of Human Rights on Article 8 in certain cases concerning housing with a view to under

This article analyses one of the recent views adopted by the Committee on Economic, Social and Cultural Rights in the communication Infante Díaz v Spain concerning the right to adequate housing under Article 11(1) of the International Covenant on Economic, Social and Cultural Rights. This view is important, as it marks the first time the CESCR found a violation of the right to adequate housing of