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Monte Carlo Simulation of Nuclear Medicine Imaging Systems

This chapter describes the use of the Monte Carlo method to simulate nuclear medicine imaging systems, mainly the scintillation camera – SPECT (Single-Photon Emission Computed Tomography) and PET (Positron Emission Tomography) – systems that are major tools in nuclear medicine to produce images of activity distributions. The first part describes the principles behind the Monte Carlo method, in par

The optimal operative protocol to accomplish CO2-EVAR resulting from a prospective interventional multicenter study

Objectives: Carbon dioxide (CO2) angiography for endovascular aortic repair (CO2-EVAR) is used to treat abdominal aortic aneurysms (AAAs), especially in patients with chronic kidney disease or allergy to iodinated contrast medium (ICM). However, some technical issues regarding the visualization of the lowest renal artery (LoRA) and the best quality image through angiographies performed from pigtai

Warming, permafrost thaw and increased nitrogen availability as drivers for plant composition and growth across the Tibetan Plateau

Permafrost-affected ecosystems are subject to warming and thawing, which can increase the availability of subsurface nitrogen (N) with consequences in otherwise N-limited tundra and alpine vegetation. Here, we quantify the extent of warming and permafrost thawing and the corresponding effects on nitrogen availability and plant growth based on a 20-year survey across 14 sites on the Tibetan Plateau

Association between left ventricular lead position and intrinsic QRS morphology with regard to clinical outcome in cardiac resynchronization therapy for heart failure

BackgroundLeft ventricular (LV) lead position may be an important factor for delivering effective cardiac resynchronization therapy (CRT). We therefore aimed to evaluate the effects of LV lead position, stratified by native QRS morphology, regarding the clinical outcome.MethodsA total of 1295 CRT-implanted patients were retrospectively evaluated. LV lead position was classified as lateral, anterio

Dyrköpt trygghet: En jämförande fallstudie om ryskt inflytande i det post-sovjetiska Centralasien

Central Asia has for a long time been called Russia’s backyard and for a good reason. The Russian influence has been an integral part of everyday life in the Central Asian region as Russia provide employment for millions of people from the region which depend heavily on remittance. Over the last three decades Russia has established several regional organizations and has been keen to integrate the

"More" work for nurses : the ironies of eHealth

BACKGROUND: eHealth applications are considered a technological fix that can potentially address some of the grand challenges in healthcare, including burnout among healthcare professionals, the growing burden of patients with chronic conditions, and retaining and recruiting healthcare professionals. However, as the deployment of eHealth applications in healthcare is relatively novel, there is a l

Effects of panic-specific cognitive behavioural and psychodynamic psychotherapies on work ability in a doubly randomised clinical trial

Objective: The effects of panic-specific psychotherapy on occupational functioning remain under-researched. This study tests whether two brief psychotherapies for Panic Disorder with or without Agoraphobia (PD/A) may generate improvement in work ability. Methods: Adults (N = 221) with a primary diagnosis of PD/A were randomised to wait-list, panic-focused psychodynamic psychotherapy (PFPP), panic

Precision Standard Model Phenomenology for High Energy Processes

The present status of particle physics is that the Standard Model has been completed with the discovery of theHiggs boson in 2012, but there is a multitude of phenomena in nature which is not accounted for by this model.Researchers are investigating possibilities for detecting new physics at the current particle physics facilities, withthe Large Hadron Collider (LHC) at the frontier. As no signifiThe present status of particle physics is that the Standard Model has been completed with the discovery of theHiggs boson in 2012, but there is a multitude of phenomena in nature which is not accounted for by this model.Researchers are investigating possibilities for detecting new physics at the current particle physics facilities, withthe Large Hadron Collider (LHC) at the frontier. As no signifi

The unhinged paradox – what does it mean for the energy system?

In man-made energy systems like the electricity system, new concepts have the potential to influence and shape the development of the system. Sometimes the influence leads to a positive development and in other cases the new concept may lead into disadvantageous pathways. In this paper we argue that when a new concept is introduced, it may give rise to an unhinged paradox. An unhinged paradox impl

The effect of uncertainty on stock market volatility and correlation

In this study, we use an extension of the heterogeneous autoregressive model to investigate the influence of time-varying risk aversion and macroeconomic, financial, and economic policy uncertainty measures on stock market volatility and correlation. Based on the findings, there is a stronger predictive ability of these variables at the monthly frequency than at the daily frequency. We also highli

An HPA-1a–positive platelet–depleting agent for prevention of fetal and neonatal alloimmune thrombocytopenia : a randomized, single-blind, placebo–controlled, single-center, phase 1/2 proof-of-concept study

Background: Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is a rare and potentially life-threatening bleeding disorder of the fetus/newborn. Antibodies against human platelet antigen 1a (HPA-1a) are associated with the most frequent FNAIT cases. There are no approved therapies for FNAIT prevention or treatment. RLYB211 is a polyclonal HPA-1a hyperimmune IgG being developed to prevent FNAIT. O

Anatomy of rocky planets formed by rapid pebble accretion : I. How icy pebbles determine the core fraction and FeO contents

We present a series of papers dedicated to modelling the accretion and differentiation of rocky planets that form by pebble accretion within the lifetime of the protoplanetary disc. In this first paper, we focus on how the accreted ice determines the distribution of iron between the mantle (oxidized FeO and FeO1.5) and the core (metallic Fe and FeS). We find that an initial primitive composition o

Field recording

Field recording, included in Davíð Brynjar Franzson's 'An Urban Archive as an English Garden' (2019).

Thrombosis risk with estrogen use for puberty induction in congenital disorders of glycosylation

Congenital disorders of glycosylation are a group of rare related disorders causing multisystem dysfunction, including ovarian failure in females that requires early estrogen replacement. Glycosylation defects also disrupt normal synthesis of several coagulation factors, increasing thrombotic risks and complicating hormone replacement. This series describes four females with different types of CDG

Extracorporeal Membrane Oxygenation: Set-up, Indications, and Complications

Extracorporeal membrane oxygenation (ECMO) occupies an increasingly important position in the clinic for the management of cardiac and/or pulmonary failure. As a rescue therapy, ECMO can support patients following respiratory or cardiac compromise to act as a bridge to recovery, to decision, or to transplant. This chapter reviews briefly the history of ECMO implementation as well as device modes,

Basic Atomic and Nuclear Physics

Nuclear medicine and molecular imaging are mostly based on radioactive elements that, when decaying due to an excess of energy, emit radiation in the form of electromagnetic radiation (photons), or by charge-particles (electron, positrons, or alpha particles). The first part of this chapter describes in general the atom and its components and states some definitions important for further reading.