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We tested the chondrogenic potential of demineralized allogeneic bone matrix (DABM) in the repair of osteochondral defects. In 42 adult rabbits, a 5-mm2 or 15-mm2 defect was created bilaterally in the intercondylar groove of distal femur. DABM was inserted directly in 37 defects, whereas in 35 it was inserted after previous placement in muscle for 4, 16, or 19 days. Another 12 defects were left em

In developing heterotopic bone in the rat, induced by allogeneic bone matrix, we immunohistochemically detected nerves containing substance P (SP), calcitonin gene-related peptide (CGRP), neuropeptide Y (NPY), vasoactive intestinal polypeptide (VIP) and tyrosine hydroxylase (TH). After 10 days they were dicernible amidst differentiating chondroblastoid cells in fibrous tissue around and within the

The surface coating of biopores plays a pivotal role in mediating mass exchange between the biopore and the soil matrix, ultimately governing preferential flow in structured soils. However, quantitative experiments of the flow exchange dynamics in the soil around an earthworm burrow (drilosphere) are limited. Here, we developed an experimental setup to mimic preferential flow within a biopore whil

Field bio-remediation techniques (FBRT) can be a low cost method to avoid the removal of top layers of soil which are rich in organic matter and bio diversity. The use of native microorganisms in FBRT is preferable because non-indigenous species can transfer their genetic material to the environment with negative impacts on the local ecological equilibrium. Petroleum Produced Water (PPW) is an imp

Civic integration is an essential part of contemporary migration control regimes. This thesis examines what happens when civic integration policy enters domestic courts, by focusing on how Sweden’s migration courts (which are part of the administrative courts) apply the income and housing requirements for family reunification.The thesis revolves around a common discussion in the legal literature,

Phase field crystal (PFC) modeling has proved to be a versatile numerical tool in the analysis of crystalline microstructures. Most often, however, the focus is put on bulk crystal behavior, while crystal defects such as grain boundaries (GBs) are less explored. This is, in particular, the case for crystal structures beyond fcc and bcc. In this work, the possibilities and challenges in adopting PF

PURPOSE: To investigate the effects of compartmental anisotropy on filtered exchange imaging (FEXI) in white matter (WM).THEORY AND METHODS: FEXI signals were measured using multiple combinations of diffusion filter and detection directions in five healthy volunteers. Additional filters, including a trace-weighted diffusion filter with trapezoidal gradients, a spherical b-tensor encoded diffusion

The ninetieth birthday of the last surviving founding father of post-WWII classical music is certainly reason enough for celebration, but what could the Lucerne Festival offer that has not already been covered by the many festivities that have taken place around the world? Fortunately, the festival has a trump card up its sleeve: the Lucerne Festival Academy, founded 11 years ago by Pierre Boulez

An atmosphere of sadness, anger and uncertainty dominated this year's Donaueschinger Musiktage. The passing in November 2014 of Armin Köhler, the artistic driving force behind the festival for the last 23 years, has left a hole that will be hard to fill. Meanwhile, due to state budget cuts Donaueschingen's orchestra-in-residence, the SWR Sinfonieorchester Freiburg und Baden-Baden, paid what will a

Creating a work today that claims to be encyclopedic is a daunting task. In the age of instant access to online resources and the pervasive reach of Wikipedia, what purpose can an old-fashioned encyclopedia seek to fulfil? In the case of The Cambridge Encyclopedia of Brass Instruments (part of an ongoing series of musical encyclopedias from CUP), the answer is evident after any casual conversation

Through his orchestral experimentation with acoustics and timbre, Richard Wagner is credited with conceptualizing, commissioning, and attempting to integrate several new labrosones into the orchestra. To greater or lesser extents, they all eventually failed to enter mainstream performance practice, but with one notable exception. Today, the contrabass tuba is a compulsory instrument for profession