Streptococcus pneumoniae (pneumococcus) is a pathogen that causes severe local and life-threatening invasive diseases, which are associated with high mortality rates. Pneumococci have evolved several strategies to evade the host immune system, including complement to disseminate and to survive in various host niches. Thus, pneumococci bind complement inhibitors such as C4b-binding protein (C4BP) a

The estrogen receptor coactivator Amplified in Breast Cancer 1 (AIB1) has been associated with an improved response to adjuvant tamoxifen in breast cancer, but also with endocrine treatment resistance. We hereby use metachronous contralateral breast cancer (CBC) developed despite prior adjuvant tamoxifen for the first tumor as an "in vivo"-model for tamoxifen resistance. AIB1-expression in the pre

Osteoporosis is a common complex disorder in postmenopausal women leading to changes in the micro-architecture of bone and increased risk of fracture. Members of the low-density lipoprotein receptor-related protein (LRP) gene family regulates the development and physiology of bone through the Wnt/β-catenin (Wnt) pathway that in turn cross-talks with the bone morphogenetic protein (BMP) pathway. In

A relatively short overview on fascism and nazism in contemporary Europe.

Abstract Conclusions: Recurrences were seen in 5% of all patients with acute mastoiditis (AM). Mastoidectomy had been performed in the majority of the patients with recurrences at their first episode of AM. Compared with the group with a single episode of AM, the recurrent group exhibited more subperiosteal and ear canal abscesses, although they were not more severely ill. It appears from this stu

Platelets contribute to blood coagulation at sites of vascular injury and to the recruitment of leukocytes at sites of inflammation. Under pathological conditions, platelets are involved in numerous diseases and clinical complications, such as deep venous thrombosis, embolism and atherosclerosis. But so far, little is known about the mechanisms of inflammation in large veins and the role of platel

Written French is known as a deep orthography, presenting important differences between the spoken and written language systems, especially as far as morphology is concerned. This exploratory study of subject-verb agreement in number illustrates the long and laborious differentiation process of spoken and written French in child learners. The focus of the study is the L2 child, who learns to speak

Artikel om bildmuseet i Berlin.

Popular Abstract in English In the past decade, mobile wireless communication have had a tremendous impact on the way people perceive and use mobile devices, most popularly the mobile phone. Apart from making phone calls, they are capable of being cameras to take pictures and videos, able to browse the Internet, do video calling and much more just like an yesteryear computer. The wireless medium iThe demand for spectrum resources in cellular systems worldwide has seen a tremendous escalation in the recent past. The mobile phones of today are capable of being cameras taking pictures and videos, able to browse the Internet, do video calling and much more than an yesteryear computer. Due to the variety and the amount of information that is being transmitted the demand for spectrum resources i

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Microalbuminuria is an early manifestation of diabetic nephropathy. Potential contributors to this condition are reduced glomerular filtration barrier (GFB) size- and charge selectivity, and impaired tubular reabsorption of filtered proteins. However, it was recently reported that no significant alterations in charge selectivity of the GFB occur in early experimental diabetic nephropathy. We here