Planning of neighborhoods that efficiently implement active solar systems (e.g., solar thermal technologies, photovoltaics) and passive solar strategies (e.g., daylight control, sunlight access through optimized buildings' morphology, cool pavements, greeneries) is increasingly important to achieve positive energy and carbon neutrality targets, as well as to create livable urban spaces. In that re

The Rieger syndrome, an autosomal dominant disorder involving ocular, dental, and umbilical defects is caused by mutations in PITX2, a Bicoid-type homeobox protein. Mouse Pitx2 mRNA is expressed in eye, tooth and umbilicus consistent with the human Riegers phenotype. Moreover, Pitx2 is involved in the Nodal/Sonic hedgehog pathway that determines left/right polarity. In this report we demonstrate a

Non-governmental organisations (NGOs) increasingly enter into “partnerships” with states to implement human rights, a phenomenon that has been studied both as a necessary inclusion of civil society in human rights practice, and as a slippery slope towards a neoliberal state retreat. What remains to be studied is how this partnership practice shapes the concepts of human rights and their duty beare

FANCM germline protein truncating variants (PTVs) are moderate-risk factors for ER-negative breast cancer. We previously described the spectrum of FANCM PTVs in 114 European breast cancer cases. In the present, larger cohort, we report the spectrum and frequency of four common and 62 rare FANCM PTVs found in 274 carriers detected among 44,803 breast cancer cases. We confirmed that p.Gln1701* was t

A search for the electroweak production of pairs of charged sleptons or charginos decaying into two-lepton final states with missing transverse momentum is presented. Two simplified models of R-parity-conserving supersymmetry are considered: direct pair-production of sleptons (ℓ~ ℓ~) , with each decaying into a charged lepton and a χ~10 neutralino, and direct pair-production of the lightest chargi

Rural perspectives in political debates are often dismissed as sentimental, narrowly self-interested, and irrational. This paper reports findings that challenge this view. Applying a deliberative systems approach, it examines how rural perspectives are articulated in Swedish public discourse. It identifies four coherent discourses that promote distinct political values: economic growth, rural cons

In response to the pressing need to address climate change and reduce global greenhouse gas (GHG) emissions, this study implemented Gaussian Mixture Models Clustering to detect the levels of GHG emissions and related socio-economic factors in 174 countries. To handle the panel data, Principal Component Analysis was conducted to achieve dimension reduction. Based on the algorithm, countries were gr

This study examined the relationship between physical activity, body image, and subjective well-being among Swedish adolescents over time. Surveying 2308 students, with 137 providing longitudinal data, we conducted a multivariate logistic regression analysis. No significant correlations were found between physical activity (p =.268), body functioning (p =.567), or body appearance (p =.075) at age

From the Brexit Referendum in 2016, up until the Brexit transition period in 2020 and onwards, the regions of the United Kingdom underwent several renegotiations within trade agreements associated with the Brexit process and the consequent withdrawal from the European Union. This caused increasing levels of economic policy uncertainty within the United Kingdom, which accordingly acted as a spillov

Osteoarthritis (OA) is a chronic degenerative joint disease, linked to age, weight and joint overload. Typical symptoms include joint pain, loss of mobility and joint stiffness. The past two decades the amount of people suffering from OA has increased, and with the current trend of increasing age and weight it is expected to further increase. It is known that knee OA is correlated with the degener

We find ourselves in the midst of a remarkable technological revolution, with rapid advancements in fields such as artificial intelligence, robotics and information technology. Consequently, there is a pressing need for low-power technologies that are not reliant on continuous power supply. The field of spintronics aims to resolve this by coupling electric and magnetic properties. To pave the way

One strategy evolved by teeth to avoid irreversible damage is to move and deform under the loads incurred during mastication. A key component in this regard is the periodontal ligament (PDL). The role of the bone underlying the PDL is less well defined. We study the interplay between the PDL and the underlying alveolar bone when loaded in the minipig. Using an Instron loading device we confirmed t

This dissertation is set in the context of the modern space age, which is characterised by an overall increase in space activities on a global scale and a relative increase in private and commercial space activities. Space has become a business case.This study analyses the principle of international responsibility for activities in outer space as mainly codified in Article VI of the Outer Space TrThis dissertation is set in the context of the modern space age, which is characterised by an overall increase in space activities on a global scale and a relative increase in private and commercial space activities. Space has become a business case.This study analyses the principle of international responsibility for activities in outer space as mainly codified in Article VI of the Outer Space Tr

The Swedish HIV/AIDS epidemic accelerated the hybridisation of welfare, as volunteer organisations rapidly professionalised and expanded their welfare services. The media’s horror scenarios prompted a sense of urgency which, in turn, motivated politicians and state funding agencies to channel large amounts of money into Swedish volunteer organisations. These included RFSL (the National Union for S

The production of π ±, K±, and (p ¯) p is measured in pp collisions at s = 13 TeV in different topological regions of the events. Particle transverse momentum (p T) spectra are measured in the “toward”, “transverse”, and “away” angular regions defined with respect to the direction of the leading particle in the event. While the toward and away regions contain the fragmentation products of the near

The increasing depletion of fossil fuels, rising greenhouse gas emissions, and a growing global population have increased the need for sustainable food and energy sources. Traditional industrial biotechnology, which relies on plant-based feedstocks, competes with food production for arable land. In contrast, marine macroalgae do not require cultivatable land, irrigation by fresh water or fertilize

Introduction: Hallux valgus (HV) is a common condition with impact on pain, function and HrQoL. International consensus does not exist on operative treatment of HV and population-level data regarding surgical treatment of HV is lacking. In this study we aimed to present base-line data from surgically treated HV patients reported to the Swedish register for foot and ankle surgery (Swefoot) during t

Risk and risk aversion are crucial concepts in finance. Models in finance typically assume a known probability distribution of returns, which does often not hold in reality. This papers aims to measure the uncertainty surrounding the probability distribution in equity markets and to evaluate if such uncertainty is priced. Our study defines uncertainty as the volatility of the option implied volati