We showed earlier that over-expression of protein kinase C (PKC) epsilon induces neurite outgrowth. The effect is mediated by a region (PKC epsilon PSC1V3) encompassing the pseudosubstrate, the two C1 domains and part of the V3 region, and is independent of the catalytic activity of the enzyme. In this region, residues immediately N-terminal of the C1b domain are crucial for neurite outgrowth. How

Artikeln diskuterar möjligheten för arkeologer att utifrån materiella källor diskutera ritual i det förflutna. Med utgångspunkt i ett avhandlingsarbete om mesolitiska gravar (Nilsson Stutz 2003) föreslås en kombination av handlingsteori och metoden ”anthropologie de terrain” som en väg till insikt. Författaren understryker behovet av att synkronisera arkeologisk teori och metod. Kan vi studera oc

Background: Reduced quadriceps strength is an early finding in subjects with knee osteoarthritis, but it is not clear whether it is a cause or a consequence of knee osteoarthritis. Objective: To determine whether reduced functional performance in the lower extremity predicts the incidence or progression of radiographic knee osteoarthritis. Design: Prospective, epidemiological, population based c

Öresund is one of the areas in the world with most ship movements. More than 40,000 ships pass through the sound in the direction north-south or the opposite every year. Other ships/ferries frequently cross the sound in the direction east-west or west-east. The ships carry goods and/or passengers in huge volumes. Since Öresund is a quite narrow sound with a difficult navigation situation, many ris

The topography of the antigen-binding site as well as the number and the positioning of the antigen contact residues are strongly correlated with the size of the antigen with which the antibody interacts. On the basis of these considerations, we have designed a focused scFv repertoire biased for haptens, designated the cavity library. The hapten-specific scFv, FITC8, was used as a scaffold for lib

The aim of the present study was to examine the influence of pregnancy on deterioration of retinopathy in patients with Type 1 diabetes mellitus. Sixty-five pregnant Type 1 diabetic women attending the University Hospital in Lund were studied retrospectively. The degree of retinopathy, and levels of HbA1c and blood pressure 12 months before, during, and 6 months after pregnancy were compared of th

Attachment of, and cell–cell fusion induced by, human cytomegalovirus were studied in the presence of neutralizing monospecific antibodies against antigenic domains 1 (AD-1) or 2 (AD-2) of glycoprotein B (gB, gpUL55). Efficient inhibition of the virion-mediated fusion event was consistently observed for the human AD-2-specific antibody as determined by a reporter gene activation assay based on per

The report contains abstracts of master theses (examensarbete) made at the Department of Automatic ControL, Lund, during the academic year 1979/80. During this year 14 theses were made by 18 students. The theses are written in Swedish with an English abstract.

Rapporten behandlar styr- och reglertekniska funktioners inverkan på energiförbrukningen i byggnader. Den omfattar presentation av undersökta objekt med beskrivning av de olika installationssystemen, redogörelse för redan gjorda driftserfarenheter samt beskrivning av energibesparande modifieringar av driftsätt.

We present direct measurements of the ultrafast carrier dynamics around buried nano-scale Schottky contacts with high spatial and time resolution, performed with a novel fermosecond near-field scanning optical microscope, It is shown that high optically excited carrier densities screen the built-in field around a Schottky contact and allow for efficient transport of electrons towards the contact,

We present approximations of varying degree of sophistication to the integral equations for the (gluon) structure functions of a hadron ("the partonic flux factor") in a model valid in the leading log approximation with a running coupling constant. The results are all of the BFKL type, i.e., a power in the Bjorken variable x(B)(-lambda) with the parameter lambda determined from the size alpha(0) o

Purpose: To compare the longitudinal suture model for bridging nerve defects with direct approximation under tension or with autologuos nerve grafting. Methods: Seven mm nerve defects in the rat sciatic nerve were repaired by either of these three methods. Evaluation was performed at twelve weeks by morphometry of the tibial nerve distal to the repair site and by weight of the gastrocnemius muscl

Ferrochelatase, the enzyme catalyzing metallation of protoporphyrin IX at the terminal step of heme biosynthesis, was co-crystallized with an isomer mixture of the potent inhibitor N-methylmesoporphyrin (N-MeMP). The X-ray structure revealed the active site of the enzyme, to which only one of the isomers was bound, and for the first time allowed characterization of the mode of porphyrin macrocycle

Denna rapport belyser översiktligt kunskapsläget rörande emissioner som härhör från byggmaterial. Några aktuella problem behandlas i rapporten.