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Hydrogen Storage Solutions in the Power-to-X Framework

Power-to-X (PtX) is an emerging approach in decarbonizing industries hard to electrify, and is in many cases requiring stable hydrogen supply to maximize production. Hydrogen is produced via electrolysis and requires large amounts of electricity, which can be expensive, especially when considering highly fluctuating electricity prices. One solution in reducing electricity related costs is to integ

Laboratory-Evolved Enzymes Provide Snapshots of the Development of Enantioconvergence in Enzyme-Catalyzed Epoxide Hydrolysis

Engineered enzyme variants of potato epoxide hydrolase (StEH1) display varying degrees of enrichment of (2R)-3-phenylpropane-1,2-diol from racemic benzyloxirane. Curiously, the observed increase in the enantiomeric excess of the (R)-diol is not only a consequence of changes in enantioselectivity for the preferred epoxide enantiomer, but also to changes in the regioselectivity of the epoxide ring o

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease

Growing evidence links neurodegenerative diseases to metal exposure. Aberrant metal ion concentrations have been noted in Alzheimer's disease (AD) brains, yet the role of metals in AD pathogenesis remains unresolved. A major factor in AD pathogenesis is considered to be aggregation of and amyloid formation by amyloid-β (Aβ) peptides. Previous studies have shown that Aβ displays specific binding to

Sci-Fi Parenthood and the End of Love

In this article, I explore concerns that have been raised regarding the relation between love and uptake of reproductive technologies, embryo selection and enhancement. Objections to (certain) uses of these technologies in terms of fractures in love, either parental or between partners, come from a variety of directions, from the conservative to the liberal. I examine two claims: (1) that the sepa

Probing the mechanisms for the selectivity and promiscuity of methyl parathion hydrolase

Diverse organophosphate hydrolases have convergently evolved the ability to hydrolyse man-made organophosphates. Thus, these enzymes are attractive model systems for studying the factors shaping enzyme functional evolution. Methyl parathion hydrolase (MPH) is an enzyme from the metallo-β-lactamase superfamily, which hydrolyses a wide range of organophosphate, aryl ester and lactone substrates. In

Competing for opium profits : The Japanese Empire and imperial subjects in Manchukuo, 1932–1937

This paper highlights the lives of Japanese and Korean subjects of Imperial Japan who were involved in opium production and circulation in Manchukuo. It discusses the dynamics, practices, and experiences of opium production and circulation. This paper provides a new reading of the diverse beneficiaries on the ground and of the opium industry in Manchukuo from the angles of production and circulati

Brott och utvisning - Om det nyligen reviderade 8 a kap. UtlL och hur det förhåller sig till krav på rättssäkerhet

Det är endast svenska medborgare som innehar en ovillkorlig rätt att vistas i Sverige. Motsatsvis åtnjuter utländska medborgare inte denna rättighet. Om en utlänning begår brott innanför Sveriges gränser kan denne, vid sidan av brottspåföljden, även utvisas ifrån riket kombinerat med ett återreseförbud som varar en viss tid eller livstid. Utvisning är således inte en brottspåföljd i lagens mening,Only Swedish citizens have an unconditional right to reside in Sweden. Conversely, foreign nationals do not enjoy this right. If a foreigner commits a crime within the borders of Sweden, they may, in addition to the criminal penalty, also be deported from the country, combined with a re-entry ban lasting a certain period of time or a lifetime. Deportation is thus not considered a criminal penalty

ARMAX-modelling with Google Trends data for prediction of changes in volume in cryptocurrencies

This thesis examines the use of ARMAX models for predicting cryptocurrency trading volumes, with Google Trends data serving as an exogenous variable. The spec- ulative nature of cryptocurrencies suggests that market sentiment, reflected in search trends, could influence trading activity. To test this hypothesis, the predictive performance of ARMAX models is compared to ARMA models across six crypt

Heart failure after left atrial appendage occlusion : Insights from the LAAOS III randomized trial

Aims: The left atrial appendage (LAA) produces natriuretic peptides and its removal or occlusion might increase the risk of heart failure (HF). We aimed to investigate the incidence of HF after LAA occlusion or removal (LAAO) in the Left Atrial Appendage Occlusion Study (LAAOS III). Methods and results: Patients (n = 4811) with atrial fibrillation (AF) and a CHA2DS2-VASc score ≥2, who were having

Discussion Seminars - A Complement to Online Teaching

After the COVID-19 pandemic, during which teachers developed a lot of online course material, teachers worldwide are challenged with how to combine online teaching with classroom teaching in an efficient way. This paper presents Discussion seminars, a teaching activity that structures discussions clearly, making it easy for students and teachers to follow the discussion. The paper puts Discussion

Tchaikovsky Symphony No. 4 with Royal Stockholm Philharmonic Orchestra

Andris Nelsons conducts and Håkan Hardenberger is soloist in a new trumpet concerto. Programme: Jörg Widmann Towards Paradise (Labyrinth VI) for trumpet and orchestra37 minEncore:Richard Rodgers My Funny Valentine, version for trumpet solo arr Håkan Hardenberger3 minPjotr Tjajkovskij Symphony No. 442 min

Reconstruction of the fluence of extreme solar particle events registered in cosmogenic proxies

Extreme solar particle events (ESPEs) are infrequent yet highly potent manifestations of solar activity. These events result in the production of significant amounts of cosmogenic isotopes (CIs): 10Be, 36Cl, and 14C, which are subsequently deposited in natural stratified archives. Analyzing CI measurements from these archives allows us to assess the particle fluxes during ESPEs. In this study, we

Mapping the ribosomal protein S7 regulatory binding site on mRNA of the E. coli streptomycin operon

In this work it is shown by deletion analysis that an intercistronic region (ICR) approximately 80 nucleotides in length is necessary for interaction with recombinant E. coli S7 protein (r6hEcoS7). A model is proposed for the interaction of S7 with two ICR sites-region of hairpin bifurcations and Shine-Dalgarno sequence of cistron S7. A de novo RNA binding site for heterologous S7 protein of Therm

An integrative analysis of reprogramming in human isogenic system identified a clone selection criterion

The pluripotency of newly developed human induced pluripotent stem cells (iPSCs) is usually characterized by physiological parameters; i.e., by their ability to maintain the undifferentiated state and to differentiate into derivatives of the 3 germ layers. Nevertheless, a molecular comparison of physiologically normal iPSCs to the "gold standard" of pluripotency, embryonic stem cells (ESCs), often

Evaluating the effectiveness of the ‘eco-cooler’ for passive home cooling

Constructed with used plastic bottles, the eco-cooler has been widely adopted in resource-poor communities in Bangladesh and other countries. We tested the eco-cooler under controlled conditions using a scientific wind tunnel in a climatic chamber. In our tests, we used seven eco-cooler designs in 27 climate conditions typical of Bangladesh (temperatures of 40 °C, 35 °C, and 30 °C; humidity levels

From 2D to 3D : Computational Methods for Analyzing Porous Electrode Structures in Fuel Cells

A fuel cell is an electrochemical device that transforms chemical energy into electrical energy and heat. It occurs through a controlled chemical reaction. Among its essential components are the porous electrodes, which play a pivotal role in the operation of the fuel cells. These electrodes are crucial because they facilitate the efficient flow of reactants to the reaction sites, thereby driving

Prevention som grund för samhället : Smittan och dess efterdyningar i dystopin Bärarna

By analysing Jessica Schiefauer’s speculative novel Bärarna (2020), this article examines the potential consequences of making disease prevention the cornerstone for an entire society. The novel is set in a future where a rabies-like disease has nearly wiped out humanity. In this dystopian setting, men, as carriers of the disease, are separated from women to prevent the resurgence of the illness.T