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Atomic Electrons as Sensitive Probes of Nuclear Properties and Astrophysical Plasma Environments : A Computational Approach

För att beskriva lagarna som styr den fysiska världen, behöver vi studera materiens struktur och hur dess olika delar växelverkar. Den grundläggande byggstenen för all känd materia i universum är atomen, vilken består av elektroner som rör sig runt en atomkärna. Atomen är ett kvantiserat mångkropparsystem, vars struktur karakteriseras av de diskreta och för ämnet unika energinivåer. Växelverkan meThis thesis deals with the relativistic modeling of atoms and ions. To interpret the stellar spectra and gain more insight from astrophysical observations, the underlying processes that generate the spectra need to be well understood and described. Examples of such processes are the interactions of atomic electrons with internal and external electromagnetic fields and with the nucleus.By exploring

Low-Dose Tamoxifen for Mammographic Density Reduction : A Randomized Controlled Trial

PURPOSE: Tamoxifen prevents breast cancer in high-risk women and reduces mortality in the adjuvant setting. Mammographic density change is a proxy for tamoxifen therapy response. We tested whether lower doses of tamoxifen were noninferior to reduce mammographic density and associated with fewer symptoms.PATIENTS AND METHODS: Women, 40-74 years of age, participating in the Swedish mammography scree

Towards circular fashion – transforming pulp mills into hubs for textile recycling

Most waste textiles are currently incinerated or landfilled, which is becoming an increasing environmental problem due to the ever-increasing consumption of textiles in the world. New recycling processes are required to address this problem and, although textile-to-textile recycling would be preferable, many researchers have suggested implementing processes based on the depolymerization of the tex

Acute myeloid leukemia in patients we judge as being older and/or unfit

Definition of older age in AML is arbitrary. In the context of the clinical studies, it starts with age ≥ 60 or ≥65 years and in recent years ≥70 or 75, depending on the selection of the studied population. In clinical practice, with older age we often mean that the patient is unfit for intensive chemotherapy. Higher age overlaps with categories such as worse performance status, unfitness, co-morb

Make disruptive technological change happen - The case of additive manufacturing

Disruptive technological change can contribute to a more abundant world. However, potentially disruptive technologies often struggle to significantly influence practice. One prominent example is additive manufacturing (AM). Although AM is often regarded as the next great technological revolution in waiting, it has not yet established itself on a large scale in many fields of application. We invest

Rituximab in Membranous Nephropathy

Membranous nephropathy (MN) is the most common cause of primary nephrotic syndrome among adults. The identification of phospholipase A2 receptor (PLA2R) as target antigen in most patients changed the management of MN dramatically, and provided a rationale for B-cell depleting agents such as rituximab. The efficacy of rituximab in inducing remission has been investigated in several studies, includi

Social considerations in the procurement of road and railroad projects in Sweden

Purpose - Social sustainability is of increasing importance in societal development, which will affect the implementation of construction projects. The social responsibilities for both construction clients and suppliers will be an increasingly relevant part of their business processes. The objective of this study is to evaluate how the procurement process functions today with respect to social con

Associations of self-reported atopic dermatitis with comorbid conditions in adults : a population-based cross-sectional study

Background: The objective of this study was to investigate the relationships between atopic dermatitis (AD) and other common chronic health conditions in adults. Methods: A cross-sectional survey was sent to a randomly selected population sample of 78,004 adults in Sweden. The questionnaires included measures of self-reported physical and mental health. Binary and multinomial logistic regression w

Combined lentiviral- and RNA-mediated CRISPR/Cas9 delivery for efficient and traceable gene editing in human hematopoietic stem and progenitor cells

The CRISPR/Cas9 system is a versatile tool for functional genomics and forward genetic screens in mammalian cells. However, it has been challenging to deliver the CRISPR components to sensitive cell types, such as primary human hematopoietic stem and progenitor cells (HSPCs), partly due to lentiviral transduction of Cas9 being extremely inefficient in these cells. Here, to overcome these hurdles,

Investigation of Heat Transfer Characteristics of Al2O3-Water Nanofluids in an Electric Heater

Commonly, heat transfer performance of a nanofluid is enhanced by increasing the mass fraction of nanoparticles due to an improvement of the thermo-physical properties. However, increasing the number of nanoparticles in the base fluid will result in an increase of the nanofluid viscosity. This research aims to investigate natural convective heat transfer for an electric heater filled with various

Energy renovation strategies for office buildings using direct ground cooling systems

Direct ground cooling systems (DGCS) can provide comfort cooling to buildings without the use of any refrigeration-based cooling methods. DGCS is an emerging technology, commonly used for new office buildings in cold climates. This study aims to evaluate the energy-saving possibilities of a DGCS compared to a conventional chiller system for an existing office building. A typical Swedish office bui

Natural and anthropogenic forcings lead to contrasting vegetation response in long-term vs. short-term timeframes

Understanding vegetation response to natural and anthropogenic forcings is vital for managing watersheds as natural ecosystems. We used a novel integrated framework to separate the impacts of natural factors (e.g. drought, precipitation and temperature) from those of anthropogenic factors (e.g. human activity) on vegetation cover change at the watershed scale. We also integrated several datasets i

Is the association between physical activity and fatigue mediated by physical function or depressive symptoms in symptomatic knee osteoarthritis? The Multicenter Osteoarthritis Study

Objectives: To examine whether physical activity (PA) was associated with fatigue, and quantify the extent of potential mediation through depressive symptoms or physical function (PF) on the relationship between PA and fatigue in symptomatic knee osteoarthritis (KOA). Method: This longitudinal study used data from the Multicenter Osteoarthritis Study (n = 484), comprising subjects aged ≥ 50 years.

Effective entrepreneurial marketing on Facebook – A longitudinal study

Social media offers a myriad of opportunities for entrepreneurial marketing strategies that leverage the power of communities, especially when they are combined with traditional approaches such as celebrity endorsement. The reach, frequency, and speed of communication on social media offer the ideal leverage for the drivers of entrepreneurial marketing. However, the rapid rate of change may threat