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Successful research funded by the European Research Council

Published 21 April 2017 Six researchers from Lund University Diabetes Centre have recieved prestigous grants from the European Research Council (ERC). In order to celebrate the success we invited the public to an open seminar. Some of the talks can be reviewed here (in Swedish). Forskning för bättre folkhälsa:Framsteg inom typ 2-diabetes, fetma och hjärtsjukdomar   Föredrag av professor Olle Melan

https://www.ludc.lu.se/article/successful-research-funded-european-research-council - 2025-03-16

From injections to pills - the research on neonatal diabetes

Published 24 May 2017 They govern everything we think and do, they give us the ability to feel pain and to secrete insulin: they are the ion channels that are present in every one of our cells and that control the electrical impulses in our nerve and muscle cells. “For me, they are the very spark of life”, says Dame Frances Ashcroft, professor at the University of Oxford, who is also now to be an

https://www.ludc.lu.se/article/injections-pills-research-neonatal-diabetes - 2025-03-16

200.000 euro to diabetes research

Published 29 May 2017 Four researchers have been awarded grants from The Bo and Kerstin Hjelt Diabetes Foundation. The grant consists of Euro 50 000 each and are aiming towards better treatments and prevention of type 2-diabetes. Improved life expectancy and quality of people with diabetesDiabetes affects millions of patients around the world. The two main types of the disease, type 1 and type 2,

https://www.ludc.lu.se/article/200000-euro-diabetes-research - 2025-03-16

The role of vitamin A in diabetes

Published 15 June 2017 There has been no known link between diabetes and vitamin A -- until now. A new study suggests that the vitamin improves the insulin producing β-cell´s function.The researchers initially discovered that insulin-producing beta-cells contain a large quantity of a cell surface receptor for vitamin A. "There are no unnecessary surface receptors in human cells. They all serve a p

https://www.ludc.lu.se/article/role-vitamin-diabetes - 2025-03-16

New research describes the differences between mice and humans

Published 3 July 2017 Research from King’s College in London, UK, and Lund University in Sweden could explain why diabetes drugs which have worked in animal experiments are not equally successful in humans. The researchers discovered differences – but also unknown similarities – in the function of insulin-producing beta cells. The team have mapped a category of receptors, known as G protein-couple

https://www.ludc.lu.se/article/new-research-describes-differences-between-mice-and-humans - 2025-03-16

LUDC-IRC ready for take off

By sara [dot] liedholm [at] med [dot] lu [dot] se (Sara Liedholm) - published 14 September 2017 Taking advantage of a novel sub-classification of diabetes LUDC-IRC, a newly launched collaboration between academia, the health care system and industry, aims at delivering precision medicine in diabetes. LUDC-IRC consolidation meeting  - We have set the bar high. We very specifically aim at making a d

https://www.ludc.lu.se/article/ludc-irc-ready-take - 2025-03-16

Newborn babies to be screened for studies on type 1 diabetes and celiac disease (gluten intolerance)

Published 17 November 2017 Can insulin taken as an infant in small doses together with food render the immune system used to insulin and thus prevent type 1 diabetes? Can a gluten-free diet and probiotics prevent celiac disease (so called gluten intolerance)? These questions will be asked by two separate studies that are being planned at Lund University in Sweden. A new comprehensive screening of

https://www.ludc.lu.se/article/newborn-babies-be-screened-studies-type-1-diabetes-and-celiac-disease-gluten-intolerance - 2025-03-16

New drink keeps blood sugar in check

Published 17 November 2017 Food researchers at Lund University in Sweden have discovered that consuming small amounts of chromium mixed with certain amino acids before eating is healthy. Why? Well, this mixture diluted in water suppresses the blood sugar spike that occurs when we eat. Now, they are hoping that the drink – which tastes like ordinary mineral water – will be able to compete with soft

https://www.ludc.lu.se/article/new-drink-keeps-blood-sugar-check - 2025-03-16

The risk of type 1 diabetes not increased by swine flu vaccine Pandemrix

Published 17 November 2017 There has been a fear that the swine flu vaccine, Pandemrix, would increase the risk of autoimmune diseases other than narcolepsy. However, a new study of children from Sweden and Finland shows that the vaccine increased neither the risk of developing autoantibodies against insulin-producing beta cells nor the occurrence of type 1 diabetes. Helena Elding Larsson “On the

https://www.ludc.lu.se/article/risk-type-1-diabetes-not-increased-swine-flu-vaccine-pandemrix - 2025-03-16

“Death receptors” – new markers for type 2 diabetes and cardiovascular disease

Published 14 December 2017 Researchers at Lund University in Sweden have found that the presence of death receptors in the blood can be used to directly measure the risk of developing cardiovascular diseases and type 2 diabetes. “We see that people with known risk factors such as high blood sugar and high blood fats also have heightened death receptor levels”, says Professor Jan Nilsson who led th

https://www.ludc.lu.se/article/death-receptors-new-markers-type-2-diabetes-and-cardiovascular-disease - 2025-03-16

Nordic conference in Malmö about Precision Medicine in the future

Published 14 December 2017 December 4-5, nordic researchers gathered in Malmö to discuss future challenges in precision medicine, a research field where diagnosis and treatment are based on the individual´s genetic and biological conditions. Focus is on our common and increasing diseases diabetes, cardiovascular disease, cancer and psychiatric diagnosis. "The goal of the meeting is to bring togeth

https://www.ludc.lu.se/article/nordic-conference-malmo-about-precision-medicine-future - 2025-03-16

Paradigm shift in the diagnosis of diabetes

Published 2 March 2018 A completely new classification of diabetes which also predicts the risk of serious complications and provides treatment suggestions. We are now seeing the first results of ANDIS – a study covering all newly diagnosed diabetics in southern Sweden — published in The Lancet Diabetes & Endocrinology. The major difference from today’s classification is that type 2 diabetes actua

https://www.ludc.lu.se/article/paradigm-shift-diagnosis-diabetes - 2025-03-16

Labour and delivery ward register data availability, quality, and utility - Every Newborn - birth indicators research tracking in hospitals (EN-BIRTH) study baseline analysis in three countries

Published 21 January 2021 Countries with the highest burden of maternal and newborn deaths and stillbirths often have little information on these deaths. Since over 81% of births worldwide now occur in facilities, using routine facility data could reduce this data gap. We assessed the availability, quality, and utility of routine labour and delivery ward register data in five hospitals in Banglade

https://www.lupop.lu.se/article/labour-and-delivery-ward-register-data-availability-quality-and-utility-every-newborn-birth - 2025-03-16

Can the validity of a cohort be improved by reweighting based on register data? Evidence from the Swedish MDC study

Published 21 January 2021 We reweighted the Malmö Diet and Cancer (MDC) study based on population register data on background variables, including socio-demographics and hospital admissions for both participants and the background population. Following individuals from baseline in 1991-1996 and at most until 2016, we studied mortality (all-cause, cancer, and CVD), incidences (cancer and CVD), and

https://www.lupop.lu.se/article/can-validity-cohort-be-improved-reweighting-based-register-data-evidence-swedish-mdc-study - 2025-03-16

NordMAN facilitates researchers’ access to Nordic microdata and provides metadata on existing Nordic registers

Published 9 April 2018 A project jointly conducted by the Nordic national statistical institutes and funded by NordForsk was initiated in 2015. The project, Nordic Microdata Access Network (NordMAN), seeks to establish a single pan-Nordic solution to facilitate researchers' access to the Nordic metadata compiled for statistical purposes, and to provide an overview of the existing Nordic registers.

https://www.lupop.lu.se/article/nordman-facilitates-researchers-access-nordic-microdata-and-provides-metadata-existing-nordic - 2025-03-16

Exploring the impact of cancer registry completeness on international cancer survival differences: a simulation study

Published 22 January 2021 Data from population-based cancer registries are often used to compare cancer survival between countries or regions. The ICBP SURVMARK-2 study is an international partnership aiming to quantify and explore the reasons behind survival differences across high-income countries. However, the magnitude and relevance of differences in cancer survival between countries have been

https://www.lupop.lu.se/article/exploring-impact-cancer-registry-completeness-international-cancer-survival-differences-simulation - 2025-03-16

Probabilistic Quantification of Bias to Combine the Strengths of Population-Based Register Data and Clinical Cohorts-Studying Mortality in Osteoarthritis

Published 22 January 2021 We propose combining population-based register data with a nested clinical cohort to correct misclassification and unmeasured confounding through probabilistic quantification of bias. We have illustrated this approach by estimating the association between knee osteoarthritis and mortality. We used the Swedish Population Register to include all persons resident in the Skån

https://www.lupop.lu.se/article/probabilistic-quantification-bias-combine-strengths-population-based-register-data-and-clinical-0 - 2025-03-16

The Validity of Intracerebral Hemorrhage Diagnoses in the Danish Patient Registry and the Danish Stroke Registry

Published 22 January 2021 Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code for ICH (ICD-10, code I61) for all patients in the Region of Southern Denmark (1.2 million) during 2009– 2017 according to either DNPR or DSR. We estimated PPVs for any non-traumatic ICH (a-ICH) and spontaneous ICH (s-ICH) alone (ie, with

https://www.lupop.lu.se/article/validity-intracerebral-hemorrhage-diagnoses-danish-patient-registry-and-danish-stroke-registry - 2025-03-16

The Israel Registry for Alzheimer’s Prevention (IRAP) Study: Design and Baseline Characteristics

Published 22 January 2021 Participants are members of the Maccabi Health Services, 40–65 years of age, with exquisitely detailed laboratory, medical diagnoses and medication data available in the Maccabi electronic medical records since 1998. Data collected through IRAP include genetic, sociodemographic, cognitive, brain imaging, lifestyle, and health-related characteristics at baseline and every

https://www.lupop.lu.se/article/israel-registry-alzheimers-prevention-irap-study-design-and-baseline-characteristics - 2025-03-16