Sökresultat

Filtyp

Din sökning på "*" gav 526348 sökträffar

Beräkning av inneklimat i luftvärmda rum

Denna rapport omfattar analys av klimat i rum som värms och ventileras med luftburen värme. Oberoende av utomhustemperatur och inre belastningsvariationer ska ett inomhusklimat åstadkommas som ger brukarna komfort i vistelsezonen. Syftet med arbetet är att ta fram en beräkningsmetod. Denna ska användas för att teoretiskt utreda om det finns någon donplacering som är bättre än andra ur termisk, hyg

Effect of cysteine mutations on direct electron transfer of horseradish peroxidase on gold

Surface exposed cysteines were genetically engineered in the structure of recombinant horseradish peroxidase (rHRP). Recombinant forms of HRP with either a His-tag or a Strep-tag at the C-terminus were produced, which additionally had cysteines at positions 57, 189 or 309 (C-terminus) of the polypeptide chain. An E coli expression system was exploited. The effect of these mutations on the direct e

Abdominal aortic aneurysm: a general defect in the vasculature with focal manifestations in the abdominal aorta?

PURPOSE: It has been suggested that abdominal aortic aneurysms (AAA) develop as a result of an alteration in the systemic connective tissue metabolism. This might change wall mechanics and diameter, not only in the AAA but also in the rest of the vascular system. This hypothesis was tested by studying the mechanical properties of AAAs as well as the common carotid artery (CCA) in the same patient

Analysis of antibody reactivity against cysteine sulfinic acid decarboxylase, a pyridoxal phosphate-dependent enzyme, in endocrine autoimmune disease

The structurally related group II pyridoxal phosphate (PLP)dependent amino acid decarboxylases glutamic acid decarboxylase (GAD), aromatic L-amino acid decarboxylase (AADC), and histidine decarboxylase (HDC) are known autoantigens in endocrine disorders. We report, for the first time, the prevalence of serum autoantibody reactivity against cysteine sulfinic acid decarboxylase (CSAD), an enzyme tha

Septicemia in granulocytopenic patients: a shift in bacterial etiology

35 episodes of septicemia in 33 patients occurred among 269 consecutive patients with granulocytopenia (granulocyte cell count less than or equal to 0.5 x 10(9)/l) during the 7-year period 1982-1988. 59% of isolated bacteria were Gram-positive (Staphylococcus aureus, Staph. epidermidis, Streptococcus species and Pneumococcus) and 41% Gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsie

The level of glucose-6-phosphate dehydrogenase activity strongly influences xylose fermentation and inhibitor sensitivity in recombinant Saccharomyces cerevisiae strains.

Disruption of the ZWF1 gene encoding glucose-6-phosphate dehydrogenase (G6PDH) has been shown to reduce the xylitol yield and the xylose consumption in the xylose-utilizing recombinant Saccharomyces cerevisiae strain TMB3255. In the present investigation we have studied the influence of different production levels of G6PDH on xylose fermentation. We used a synthetic promoter library and the copper

Effects of palatable diets on appetite regulation, appetite peptides and neurogenesis.

Popular Abstract in Swedish Fetma ökar epidemilikt i hela världen, delvis på grund av en ökad konsumption av dieter som innehåller mycket fett och/eller socker. Ghrelin och leptin är hormoner som produceras perifert med effekter på födointag och energihomeostas. Ghrelin i cirkulationen ökar vid energibrist, t ex vid fasta och signalerar därmed hunger. Leptin ökar vid födointag och signalerar mättnObesity is increasing throughout the world at an epidemic rate, partly due to increased consumption of diets rich in fat and/or sugar. Ghrelin and leptin are hormones, originating from the periphery, involved in the regulation of food intake and of maintaining energy homeostasis. Circulating ghrelin levels increase in times of energy deficiency, such as fasting, signalling hunger whereas circulati

Automated flow enzyme-linked immunosorbent assay (ELISA) system for analysis of methyl parathion

sensitive detection of pesticides is of utmost importance in environment pesticides in agricultural and environmental samples wherein antibodies are employed against the target molecules. Accurate diagnosis depends on the affinity and specificity of the antibody preparation used, and high affinity antibodies are essential for the detection of very small amounts of pesticides. Enzyme linked immuno

Cataract surgery and quality of life in patients with age related macular degeneration.

Background: The coexistence of cataract and age related macular degeneration (AMD) is not unusual, especially in the very elderly. The outcome of cataract surgery in these cases depends on the effect of AMD on vision. In this study the authors have compared the outcome of cataract patients with AMD to that of cataract patients with no vision threatening ocular comorbidity, and analysed possible pr

Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease.

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG-expansion in the gene encoding the protein huntingtin. The disease is characterized by progressive motor disturbances, cognitive defects, dementia, and weight loss. Using western blotting and immunohistochemistry we have assessed the expression levels and patterns of a number of proteins involved in neuro

Transient Control of a Multi Cylinder HCCI Engine During a Drive Cycle

This study applies a state feedback-based Closed-Loop Combustion Control (CLCC) using Fast Thermal Management (FTM) on a multi-cylinder Variable Compression Ratio (VCR) engine. At speeds above 1500 rpm is the FTM's bandwidth broadened by using the VCR feature of this engine, according to a predefined map, which is a function of load and engine speed. Below 1500 rpm is the PID-based CLCC using VCR

Influence of dissolved gas on the interaction between hydrophobic surfaces in water

We analyze how the interaction between two hydrophobic surfaces in water depends on the amount of dissolved gas. At equilibrium there is, for a truly hydrophobic surface with contact angle theta > 90degrees, a long range attractive force. The attraction is due to the formation of a gaseous film between the surfaces. For a completely degassed sample the gas consists of water vapor and the range of

Studies of the role of complement factor H in hemolytic uremic syndrome

Popular Abstract in Swedish Faktor H är den viktigaste cirkulerande hämmare av den alternativa komplementvägen. Den fungerar som co-faktor för faktor-I medierad C3b nedbrytning, hindrar bildning av C3bBb konvertas och främjar dess nedbrytning. Genom att skilja mellan kroppens egna och främmande celler kan faktor H inhibera komplementmedierad värdcellsskada. Mutationer i faktor H har hittats hos paFactor H is the main fluid phase regulator of the alternative pathway of complement. Factor H acts as a co-factor for factor I-mediated C3b degradation, inhibits the formation of the C3bBb convertase and accelerates its decay. By discriminating between host and foreign cells, factor H inhibits complement-mediated injury to host cells. Factor H mutations have been associated with atypical hemolytic

Slutredovisning från projekten "Brandteknisk dimensionering baserad på beräkning" (SBUF) och "Funktionsbaserad brandteknisk dimensionering" (Branndforsk)

This is a summary report of two integrated three year projects "Fire safety design based on calculations" and "Performance based fire safety design". The total project has been subdivided into several part projects: general principles for risk assessment, evacuation safety of public buildings, hotels and health care buildings, calculation of safety factors, calculation of model uncertainties, unce